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NSL1

  • Official Full Name

    NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)

  • Overview

    This gene encodes a protein with two coiled-coil domains that localizes to kinetochores, which are chromosome-associated structures that attach to microtubules and mediate chromosome movements during cell division. The encoded protein is part of a conserved protein complex that includes two chromodomain-containing proteins and a component of the outer plate of the kinetochore. This protein complex is proposed to bridge centromeric heterochromatin with the outer kinetochore structure. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    NSL1; NSL1, MIND kinetochore complex component, homolog (S. cerevisiae); C1orf48, chromosome 1 open reading frame 48; kinetochore-associated protein NSL1 homolog; DC8; DKFZP566O1646; MIS14; 4833432M17Rik; AI451597; C1orf48; DC31; Gm105; Gm984; Kinetochore associated protein NSL1 homolog;
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NSL1-260H Recombinant Human NSL1, MIS12 kinetochore complex component, His-tagged E.coli His
Human NSL1-442HCL Recombinant Human NSL1 lysate HEK293 N/A
Zebrafish NSL1-3138Z Recombinant Zebrafish NSL1 Mammalian Cell His
Chicken NSL1-3438C Recombinant Chicken NSL1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

NSL1 involved in several pathways and played different roles in them. We selected most pathways NSL1 participated on our site, such as Cell Cycle, Cell Cycle, Mitotic, M Phase, which may be useful for your reference. Also, other proteins which involved in the same pathway with NSL1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Cell CycleKIF2B;CDC14A;SMC3;CEP135;E2F3;MCM9;TUBGCP5;ORC2L;TUBB4A
Cell Cycle, MitoticNSL1;GOLGA2;MAPRE1A;SPDL1;CENPJ;CLIP1;NEDD1;TUBGCP4;ZW10
M PhaseNCAPD3;PMF1;SPC25;RCC2;NIPBLA;NUF2;KIF18A;CENPK;SET
Mitotic AnaphaseITGB3BP;ZW10;PMF1;VRK1;VRK2;CENPN;CENPL;NUDC;SKA2
Mitotic Metaphase and AnaphasePDS5B;CLIP1;CDCA5;CCDC99;PDS5A;SKA2;WAPAL;NSL1;PANE1
Mitotic PrometaphaseMIS12;CENPP;CDCA5;ZWINT;SPC24;NUF2;NCAPG;WAPAL;PDS5A
RHO GTPase EffectorsNCKIPSD;KIF14;FMNL2;RHOC;ABI1;SPDL1;NCKAP1;ACTR2B;ERCC6L
RHO GTPases Activate ForminsMKL1B;FMNL1;SGOL2;RANGAP1B;ZWINT;SKA2;RHOAE;ZWILCH;MKL1

NSL1 has several biochemical functions, for example, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NSL1 itself. We selected most functions NSL1 had, and list some proteins which have the same functions with NSL1. You can find most of the proteins on our site.

Function Related Protein
protein bindingPRDM4;AMMECR1;EIF5;ARFGAP1;TFPT;ACY3;EIF5A2;GIT2;RABIF

NSL1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NSL1 here. Most of them are supplied by our site. Hope this information will be useful for your research of NSL1.

MIS12; ZWINT; Casc5; Mis12; LRRK2; Bub1; BUB1; Ndc80; Bub1b; G6PC; CBX5; YWHAZ; CBX3; SPC24

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