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NT5C

  • Official Full Name

    5, 3-nucleotidase, cytosolic

  • Overview

    This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5 deoxyribonucleotides (dNTP) and 2(3)-dNTP and ribonucleotides, but not 5 ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene.
  • Synonyms

    NT5C; 5, 3-nucleotidase, cytosolic; 5 nucleotidase, deoxy (pyrimidine), cytosolic type C , UMPH2, uridine 5 prime monophosphate hydrolase 2; 5(3)-deoxyribonucleotidase, cytosolic type; cdN; DNT 1; DNT1; PN I; deoxy-5-nucleotidase 1; cytosolic 5,3-;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian cells
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • N
  • His
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NT5C-1074H Recombinant Human NT5C protein, His & T7-tagged E.coli His/T7 Asp12~Leu200
Human NT5C-1380H Recombinant Human NT5C, GST-tagged E.coli GST 1-201aa
Human NT5C-1225HCL Recombinant Human NT5C cell lysate N/A
Human NT5C-6577H Recombinant Human NT5C Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human NT5C-2153HFL Recombinant Full Length Human NT5C Protein, C-Flag-tagged Mammalian cells Flag
Human NT5C-1554H-B Recombinant Human NT5C Protein Pre-coupled Magnetic Beads HEK293
Human NT5C-1554H Recombinant Human NT5C Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Nt5c-1865M Recombinant Mouse Nt5c Protein, His-tagged E.coli N-His Asp12-Leu200
Mouse Nt5c-4513M Recombinant Mouse Nt5c Protein, Myc/DDK-tagged HEK293T Myc/DDK
  • Involved Pathway
  • Protein Function
  • Interacting Protein

NT5C involved in several pathways and played different roles in them. We selected most pathways NT5C participated on our site, such as Purine metabolism, Pyrimidine metabolism, Nicotinate and nicotinamide metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with NT5C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Purine metabolismIMPDH1A;PAICS;PDE6H;PKMB;POLR2GL;POLR3GL;TWISTNB;Adcy4;PDE3B
Pyrimidine metabolismCMPK1;POLR2K;POLR2G;NT5M;POLR2F;POLR3A;TK2;UCKL1;POLR2C
Nicotinate and nicotinamide metabolismNADK2;NT5M;KCNG4;NT5C1B-RDH14;ITGB1BP3;NMNAT3;PNP5A;AOX4;NAMPTB
Metabolic pathwaysALDOAA;SDSL;SMPD4;ALG12;PLA2G4F;P4HA1A;NDUFC1;PDHB;PIPOX

NT5C has several biochemical functions, for example, 5-nucleotidase activity, metal ion binding, nucleotidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NT5C itself. We selected most functions NT5C had, and list some proteins which have the same functions with NT5C. You can find most of the proteins on our site.

Function Related Protein
5-nucleotidase activityNT5DC1;NT5C1BA;NT5DC2;NT5M;NT5C2L1;ACPP;NT5C;NT5C1B;NT5C3A
metal ion bindingCOL27A1;LMTK3;IKZF4;TRIM36;PPARG;ZNF311;CRYAB;ZFP161;NR6A1A
nucleotidase activityNT5C;NT5M
pyrimidine nucleotide binding

NT5C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NT5C here. Most of them are supplied by our site. Hope this information will be useful for your research of NT5C.

TNS2; 2_aha_camp

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