Nt5e
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Official Full Name
5 nucleotidase, ecto
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Overview
CD73 (ecto-5`-nucleotidase) is a 69-kd GPI-anchored surface protein.In mouse, expression of CD73 in bone marrow is restricted to the CD11b+ myeloid cells.In spleen it is largely expressed on T cells. -
Synonyms
NT5E; 5 nucleotidase, ecto; 5-nucleotidase; 5-NT; ecto-5-nucleotidase; NT; Nt5; eNT; CD73; AI447961; 2210401F01Rik;
- Recombinant Proteins
- Cell & Tissue Lysates
- Antibody
- Cattle
- Cynomolgus Monkey
- Human
- Mouse
- Rat
- Zebrafish
- CHO
- E.coli
- HEK293
- Human Cell
- Human cells
- Mammalian Cell
- Mammalian cells
- Mouse
- Wheat Germ
- C
- His
- Fc
- GST
- hFc
- Myc
- His|T7
- N/A
- N
- Involved Pathway
- Protein Function
- Interacting Protein
- Nt5e Related Research Area
Nt5e involved in several pathways and played different roles in them. We selected most pathways Nt5e participated on our site, such as Purine metabolism, Pyrimidine metabolism, Nicotinate and nicotinamide metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with Nt5e were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Purine metabolism | POLD4;PDE4A;PRPS1A;PKM;PRIM1;PDE3A;PDE1A;NTPCR;PRPS1 |
| Pyrimidine metabolism | UCK2A;POLR1E;POLR2J3;POLR2C;DPYDA.1;NME2A;NME2B.2;UCK2;CDA |
| Nicotinate and nicotinamide metabolism | KCNG4;NT5E;MIBP;NNMT;NT5C1A;ITGB1BP3;PNP6;ENPP3;NMNAT1 |
| Metabolic pathways | IL4I1;ENO2;ATIC;ACAA1;DHDPSL;ACLY;HMGCL;NAMPT;APRT |
Nt5e has several biochemical functions, for example, 5-nucleotidase activity, ferrous iron binding, nucleotide binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Nt5e itself. We selected most functions Nt5e had, and list some proteins which have the same functions with Nt5e. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| 5-nucleotidase activity | NT5DC2;NT5C3B;NT5C3L;NT5C1B;NT5DC3;ACPP;NT5C2;NT5C3A;NT5DC1 |
| ferrous iron binding | FTO;Trf;FECH;TET2;PLOD1;TRR1;ISCA1;CDO1;TH |
| nucleotide binding | SRSF12;TOR2A;ATP1A1A.5;CSTF2T;PSMC1B;UBE1Y1;PUF60B;GNAIA;HNRPL |
Nt5e has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Nt5e here. Most of them are supplied by our site. Hope this information will be useful for your research of Nt5e.
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- Q&As
- Reviews
Q&As (5)
Ask a questionYes, elevated levels of NT5E have been observed in various diseases, making it a potential biomarker for conditions such as cancer and autoimmune disorders.
NT5E-generated adenosine has anti-inflammatory effects, and modulating NT5E activity is being explored as a potential therapeutic strategy for inflammatory conditions.
Yes, NT5E is implicated in autoimmune diseases, and targeting its activity is being investigated for potential therapeutic interventions.
As of my last knowledge update in January 2022, there were no FDA-approved drugs specifically targeting NT5E, but research in this area is ongoing.
NT5E-generated adenosine is neuroprotective, and research is exploring its potential in the treatment of neurodegenerative disorders.
Customer Reviews (3)
Write a reviewthe manufacturer's support plays a crucial role in the successful implementation of trials involving the NT5E protein.
The manufacturer maintains stringent quality control measures to ensure the purity and stability of the protein, minimizing experimental variability and maximizing the accuracy of the data obtained.
Their responsiveness to inquiries and willingness to address concerns contribute to a smooth and productive research experience.
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