NUDT10
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Official Full Name
nudix (nucleoside diphosphate linked moiety X)-type motif 10
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Overview
NUDT10 belongs to a subgroup of phosphohydrolases that preferentially attack diphosphoinositol polyphosphates (Hidaka et al., 2002 -
Synonyms
NUDT10; nudix (nucleoside diphosphate linked moiety X)-type motif 10; diphosphoinositol polyphosphate phosphohydrolase 3-alpha; DIPP3a; hDIPP3alpha; 5-P1; APS 2; APS2; Diadenosine 5 5 P1 P6 hexaphosphate hydrolase 3 alpha; Diadenosine 5; Diphosphoinositol polyphosphate phosphohydrolase type 3 alpha; DIPP 3 alpha; DIPP 3a; DIPP-3-alpha; DIPP3 alpha; DIPP3-alpha; hAps 2; hAps2; Nucleoside diphosphate linked moiety X motif 10; Nucleoside diphosphate-linked moiety X motif 10; NUD10_HUMAN; Nudix (nucleoside diphosphate linked moiety X) type motif 10; Nudix motif 10; Nudix type motif 10; NUDT 10; P6-hexaphosphate hydrolase 3-alpha; OTTHUMP00000023299; diadenosine 5,5-P1,P6-hexaphosphate hydrolase 3-alpha; diphosphoinositol polyphosphate;
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | NUDT10-28046TH | Recombinant Human NUDT10, His-tagged | E.coli | His | 164 amino acids |
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| Human | NUDT10-1399H | Recombinant Human NUDT10, GST-tagged | E.coli | GST | 1-164aa | |
| Human | NUDT10-982H | Recombinant Human NUDT10, His-tagged | E.coli | His |
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| Human | NUDT10-3654HCL | Recombinant Human NUDT10 293 Cell Lysate | HEK293 | N/A |
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| Human | NUDT10-6709H | Recombinant Human NUDT10 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK |
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- Involved Pathway
- Protein Function
- Interacting Protein
NUDT10 involved in several pathways and played different roles in them. We selected most pathways NUDT10 participated on our site, such as Inositol phosphate metabolism, Metabolism, Synthesis of pyrophosphates in the cytosol, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Inositol phosphate metabolism | TPI1;PLCZ1;ITPKA;MTMR7;TPI1B;NUDT10;INPP5KA;MTMR6;INPP5D |
| Metabolism | G0S2;CERS4A;MED9;PDPR;PDK4;APOA5;CYP2F1;IP6K3;CYGB1 |
| Synthesis of pyrophosphates in the cytosol | NUDT10;NUDT4B;NUDT4A;NUDT3A;NUDT3;NUDT11;NUDT4;IP6K3;NUDT3B |
NUDT10 has several biochemical functions, for example, diphosphoinositol-polyphosphate diphosphatase activity, inositol diphosphate tetrakisphosphate diphosphatase activity, inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT10 itself. We selected most functions NUDT10 had, and list some proteins which have the same functions with NUDT10. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| diphosphoinositol-polyphosphate diphosphatase activity | NUDT4;NUDT10;NUDT3;NUDT11 |
| inositol diphosphate tetrakisphosphate diphosphatase activity | NUDT3;NUDT10;NUDT4;NUDT11 |
| inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 1-diphosphatase activity | NUDT4;NUDT10;NUDT11;NUDT3 |
| inositol-1,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity | NUDT4;NUDT3;NUDT11;NUDT10 |
| inositol-1-diphosphate-2,3,4,5,6-pentakisphosphate diphosphatase activity | NUDT11;NUDT3;NUDT10;NUDT4 |
| inositol-3,5-bisdiphosphate-2,3,4,6-tetrakisphosphate 5-diphosphatase activity | NUDT11;NUDT3;NUDT4;NUDT10 |
| inositol-3-diphosphate-1,2,4,5,6-pentakisphosphate diphosphatase activity | NUDT3;NUDT4;NUDT10;NUDT11 |
| inositol-5-diphosphate-1,2,3,4,6-pentakisphosphate diphosphatase activity | NUDT4;NUDT3;NUDT10;NUDT11 |
| metal ion binding | BMI1A;HIC1L;PIR;BCL11A;STAMBP;ZDHHC18;SALL2;COPS5;PATZ1 |
| protein binding | STAU2;DEPDC1;DACT1;SVIL;ZNF460;ADAM15;PGK1;UBE2K;ERCC6 |
NUDT10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT10 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT10.
SNAPC5; TCF4; MTUS2; ddhA; RASSF1
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