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METAP1

  • Official Full Name

    methionyl aminopeptidase 1

  • Overview

    Removes the amino-terminal methionine from nascent proteins. Required for normal progression through the cell cycle.
  • Synonyms

    METAP1; methionyl aminopeptidase 1; methionine aminopeptidase 1; KIAA0094; MAP1A; MetAP1A; Peptidase M; DKFZp781C0419; MAP 1; MetAP 1; Peptidase M 1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • In Vitro Cell Free System
  • Insect Cell
  • Mammalian Cell
  • Wheat Germ
  • GST
  • hFc
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • T7|His
  • Tag Free
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human METAP1-1960H Recombinant Human Methionyl Aminopeptidase 1, His-tagged E.coli His
Human METAP1-15849H Recombinant Human METAP1, His-tagged E.coli His 1-386aa
Human METAP1-307H Recombinant Human METAP1 protein, hFc-tagged HEK293 hFc Met1-Phe272
Human NUDT16-1572H Recombinant Human DCP5 protein E.coli N/A
Human NUDT16-152H Recombinant Human NUDT16 Protein, His-tagged E.coli His 2-195
Human NUDT16-954H Recombinant Human NUDT16, His-tagged E.coli His
Human NUDT16-237H Recombinant Human NUDT16 protein, T7/His-tagged E.coli T7/His
Human NUDT16-151H Recombinant Human NUDT16 Protein, GST-tagged E.coli GST 2-195
Human METAP1-202H Recombinant Human METAP1 Protein, His-tagged Insect Cell His
Human METAP1-2887HCL Recombinant Human METAP1 cell lysate Human Cell N/A
Human NUDT16-447HCL Recombinant Human NUDT16 lysate HEK293 N/A
Human METAP1-4134H Recombinant Human METAP1 Protein (Met1-Phe386) E.coli Tag Free Met1-Phe386
Human METAP1-945H Recombinant Human METAP1 Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human NUDT16-2326H Recombinant Human NUDT16 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human METAP1-4416H Recombinant Human METAP1 Protein, GST-tagged Wheat Germ GST
Human METAP1-3777H Recombinant Human METAP1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human METAP1-6150HF Recombinant Full Length Human METAP1 Protein, GST-tagged In Vitro Cell Free System GST 272 amino acids
Mouse NUDT16-10966M Recombinant Mouse NUDT16 Protein Mammalian Cell His
Mouse METAP1-5484M Recombinant Mouse METAP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse METAP1-5484M-B Recombinant Mouse METAP1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Metap1-4039M Recombinant Mouse Metap1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque METAP1-2735R Recombinant Rhesus monkey METAP1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque NUDT16-3125R Recombinant Rhesus monkey NUDT16 Protein, His-tagged Mammalian Cell His
Rhesus Macaque METAP1-2555R-B Recombinant Rhesus Macaque METAP1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque METAP1-2555R Recombinant Rhesus Macaque METAP1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish METAP1-3070Z Recombinant Zebrafish METAP1 Mammalian Cell His
Chicken METAP1-2823C Recombinant Chicken METAP1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • METAP1 Related Articles
  • METAP1 Related Research Area

METAP1 involved in several pathways and played different roles in them. We selected most pathways METAP1 participated on our site, such as Inactivation, recovery and regulation of the phototransduction cascade, Signal Transduction, The phototransduction cascade, which may be useful for your reference. Also, other proteins which involved in the same pathway with METAP1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Inactivation, recovery and regulation of the phototransduction cascadeNMT2;METAP1;GRK7;METAP2;SAGB;RLN1;NMT1;METAP2B;METAP2A
Signal TransductionTLE3B;ARHGAP9;MKL1;IFT172;DEPDC1B;ROR1;SOX9B;TMED5;TJP2B
The phototransduction cascadeNMT1A;METAP1;METAP2B;CNGA1;METAP2A;NMT1B;RLN1;SAGB;GRK7
Visual phototransductionMETAP2A;SAGB;RDH12;NMT1A;ABCA4A;SDR9C7;APOM;METAP2;MYO7AA

METAP1 has several biochemical functions, for example, aminopeptidase activity, metal ion binding, metalloexopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by METAP1 itself. We selected most functions METAP1 had, and list some proteins which have the same functions with METAP1. You can find most of the proteins on our site.

Function Related Protein
aminopeptidase activityNPEPL1;TPP2;ERAP1;METAP1D;NPEPPS;CTSH;LNPEP;ANPEP;PHEX
metal ion bindingPPP4CA;ZNRF2B;EFCAB11;ZFR;DNTT;STEAP3;MORC4;FTH1B;GALNT11
metalloexopeptidase activityMETAP2A;NUDT16;METAP2B;METAP1D;METAP1;LAP3;DPEP1;RNPEP;METAP2

METAP1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with METAP1 here. Most of them are supplied by our site. Hope this information will be useful for your research of METAP1.

CBWD1; SMAD9; HNRNPU

Ahsan, F; Arif, A; et al. Characterization and bioassay of post-translationally modified interferon alpha-2b expressed in Escherichia coli. JOURNAL OF BIOTECHNOLOGY 184:11-16(2014).
Poreba, M; Gajda, A; et al. S1 pocket fingerprints of human and bacterial methionine aminopeptidases determined using fluorogenic libraries of substrates and phosphorus based inhibitors. BIOCHIMIE 94:704-710(2012).
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