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NUDT21

Official Full Name

nudix (nucleoside diphosphate linked moiety X)-type motif 21
Overview

The protein encoded by this gene is one subunit of a cleavage factor required for 3 RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3 end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides.
Synonyms

NUDT21; nudix (nucleoside diphosphate linked moiety X)-type motif 21; cleavage and polyadenylation specific factor 5, 25 kD subunit , cleavage and polyadenylation specific factor 5, 25 kDa , CPSF5; cleavage and polyadenylation specificity factor subunit;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NUDT21-1816H	Recombinant Human NUDT21 Protein, GST-tagged	Wheat Germ	GST		Inquiry
Human	NUDT21-960H	Recombinant Human NUDT21, His-tagged	E.coli	His		Inquiry
Human	NUDT21-27532TH	Recombinant Human NUDT21, His-tagged	E.coli	His	227 amino acids	Inquiry
Human	NUDT21-3646HCL	Recombinant Human NUDT21 293 Cell Lysate	HEK293	N/A		Inquiry
Human	NUDT21-5940H	Recombinant Human NUDT21 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	NUDT21-2211HF	Recombinant Full Length Human NUDT21 Protein, GST-tagged	In Vitro Cell Free System	GST	227 amino acids	Inquiry
Mouse	NUDT21-10972M	Recombinant Mouse NUDT21 Protein	Mammalian Cell	His		Inquiry
Mouse	NUDT21-6256M-B	Recombinant Mouse NUDT21 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	NUDT21-6256M	Recombinant Mouse NUDT21 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	Nudt21-4540M	Recombinant Mouse Nudt21 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Chicken	NUDT21-5051C	Recombinant Chicken NUDT21	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

NUDT21 involved in several pathways and played different roles in them. We selected most pathways NUDT21 participated on our site, such as Cleavage of Growing Transcript in the Termination Region, Gene Expression, Processing of Capped Intron-Containing Pre-mRNA, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT21 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Cleavage of Growing Transcript in the Termination Region	SRSF11;CSTF2;U2AF2;THOC4;SLBP;LSM11;LSM10;CSTF3;PAPOLA
Gene Expression	NR6A1A;KHSRP;SKIB;NR0B2A;HNRNPA0A;COX6B1;ZNF324;ZNF74;ZNF561
Processing of Capped Intron-Containing Pre-mRNA	NXF1;THOC4;SLBP;CLP1;SF3B4;RNPS1;SRSF11;YBX1;HNRNPA2B1
Processing of Capped Intronless Pre-mRNA	CSTF1;CSTF3;PAPOLA;ZNF473;LSM10;NUDT21;CSTF2;LSM11;CLP1
Processing of Intronless Pre-mRNAs	CSTF3;PAPOLA;NUDT21;CSTF1;CSTF2;CLP1
RNA Polymerase II Transcription	CCNT2A;SLBP;SSRP1A;CSTF1;THOC4;U2AF2;CCNT2B;RNPS1;CLP1
RNA Polymerase II Transcription Termination	CSTF1;U2AF2;CLP1;NUDT21;ZNF473;SRSF11;THOC4;CSTF3;LSM11
mRNA 3-end processing	CSTF3;CSTF2;NUDT21;SFRS3A;SRSF11;CLP1

NUDT21 has several biochemical functions, for example, AU-rich element binding, contributes_to RNA binding, histone deacetylase binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT21 itself. We selected most functions NUDT21 had, and list some proteins which have the same functions with NUDT21. You can find most of the proteins on our site.

Function	Related Protein
AU-rich element binding	DND1;ZFP36L3;EXOSC8;ELAVL4;HNRNPA0;ZFP36;CPSF5;TIAL1;EXOSC4
contributes_to RNA binding	LSM7;SMX5;CPSF6;NUDT21
histone deacetylase binding	TRAF6;ZNF703;PKN1;SOD3;MAGEA1;SP2;KAT2A;KAT2B;PRDM1
hydrolase activity	SYNJ1;ATP1A3A;OTUD4;LTV1;SACM1L;RNASEKA;ACP5A;ACOT5;GPN3
mRNA binding	PTBP2;CELF3;NOVA1;HNRNPAB;CSTF2;SNRNP35;RPL13A;AGO2;RPS26
poly(A) RNA binding	FUBP1;HMGB3;NUFIP2;UBAP2;RPS2;MRPS26;CD3EAP;IGF2BP1;NOC4L
protein binding	USP15;C2orf28;PDCD1;EIF2B2;TMEM132D;SCEL;PMAIP1;CA4;CLTB
protein homodimerization activity	TMEM173;YARS2;HNF1A;GYS2;ACOT7;CHKA;DGAT2;IKZF4;ECT2

NUDT21 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT21 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT21.

CPSF7; CPSF6; TRIM27; GOLGA2; RNPS1