NUDT9
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Official Full Name
nudix (nucleoside diphosphate linked moiety X)-type motif 9
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Overview
The protein encoded by this gene belongs to the Nudix hydrolase family. Nudix boxes are found in a family of diverse enzymes that catalyze the hydrolysis of nucleoside diphosphate derivatives. This enzyme is an ADP-ribose pyrophosphatase that catalyzes the hydrolysis of ADP-ribose to AMP and ribose-5-P. It requires divalent metal ions and an intact Nudix motif for enzymatic activity. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. -
Synonyms
NUDT9; nudix (nucleoside diphosphate linked moiety X)-type motif 9; ADP-ribose pyrophosphatase, mitochondrial; MGC3037; mitochondrial; Adenosine diphosphoribose pyrophosphatase; ADP ribose diphosphatase; ADP ribose phosphohydrolase; ADP ribose pyrophosphatase, mitochondrial precursor; ADP-ribose diphosphatase; ADP-ribose phosphohydrolase; ADP-ribose pyrophosphatase; ADPR PPase; ADPR-PPase; EC 3.6.1.13; Nucleoside diphosphate linked moiety X motif 9; Nucleoside diphosphate-linked moiety X motif 9; Nudix motif 9; NUDT9_HUMAN; ADP-ribose pyrosphosphatase NUDT9; nucleoside diphosphate linked moiety X-type motif 9; NUDT10;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
NUDT9 involved in several pathways and played different roles in them. We selected most pathways NUDT9 participated on our site, such as Purine metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUDT9 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Purine metabolism | DGUOK;RRM2B;PDE5A;POLR2I;GUK1B;ALLC;PNP6;POLE4;PAPSS1 |
NUDT9 has several biochemical functions, for example, ADP-ribose diphosphatase activity, ADP-sugar diphosphatase activity, adenosine-diphosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by NUDT9 itself. We selected most functions NUDT9 had, and list some proteins which have the same functions with NUDT9. You can find most of the proteins on our site.
Function | Related Protein |
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ADP-ribose diphosphatase activity | NUDT14;NUDT9;ADPRM;NUDT5;TRPM2 |
ADP-sugar diphosphatase activity | NUDT5;NUDT9 |
adenosine-diphosphatase activity | ENTPD2;NUDT9;SLC25A42 |
NUDT9 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUDT9 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUDT9.
MDM2; EPHA2
- Q&As
- Reviews
Q&As (5)
Ask a questionNUDT9 protein has been found to modulate inflammatory responses in immune cells, suggesting a potential role in inflammatory diseases.
NUDT9 protein is involved in the repair of DNA damage, and its dysregulation has been linked to genomic instability in cancer cells.
There is potential for NUDT9 protein to be used as a target for personalized medicine, especially in the context of cancer treatment based on specific genetic mutations.
Yes, preclinical studies have suggested that NUDT9 protein may play a role in cardiovascular diseases, and it is being studied as a potential therapeutic target.
Yes, research suggests that NUDT9 protein may be involved in the pathogenesis of neurodegenerative diseases, and it is being investigated as a potential therapeutic target.
Customer Reviews (3)
Write a reviewWith its high purity and stability, this protein ensures dependable and accurate results, which are crucial for the success of my research endeavors.
The NUDT9 protein is renowned for its exceptional quality and reliability, making it an ideal choice to fulfill my experimental requirements.
Whether it is for investigating cellular pathways, studying protein functions, or exploring signaling cascades, the NUDT9 protein offers unparalleled versatility and performance.
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