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NUP98

  • Official Full Name

    NUP98 nucleoporin 98kDa

  • Overview

    Nucleoporin 98 (Nup98) is a component of nuclear pore complex (NPC). This protein plays a critical role in nuclear trafficking. Nup98 plays a specific role in the RNA export.
  • Synonyms

    NUP98; nucleoporin 98kDa; nucleoporin 98kD; nuclear pore complex protein Nup98-Nup96; NUP96; Nup98-Nup96; GLFG-repeat containing nucleoporin; ADIR2; NUP196;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian cell
  • Mammalian Cell
  • hFc
  • hFC
  • His
  • GST
  • His|T7
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human NUP98-5792H Recombinant Human NUP98 protein, His-tagged E.coli His Gln629~Pro894
Human NUP98-1235HCL Recombinant Human NUP98 cell lysate N/A
Human NUP98-5793H Recombinant Human NUP98 protein, hFC-tagged HEK293 hFC Partial
Human NUP98-4443H Recombinant Human NUP98 protein, hFc-tagged Mammalian cell hFc 1-880aa
Mouse Nup98-5793M Recombinant Mouse Nup98 protein, His & T7-tagged E.coli His/T7 Thr568~Tyr776 (Accession # Q6PFD9)
Mouse NUP98-3235M Recombinant Mouse NUP98 protein, His-GST-tagged E.coli His/GST Thr568~Tyr776
Zebrafish NUP98-10953Z Recombinant Zebrafish NUP98 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • NUP98 Related Articles

NUP98 involved in several pathways and played different roles in them. We selected most pathways NUP98 participated on our site, such as RNA transport, Influenza A, which may be useful for your reference. Also, other proteins which involved in the same pathway with NUP98 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
RNA transportNDC1;GEMIN6;SEC13;THOC2;EIF4A3;SRRM1;EIF3EB;EIF3HB;EIF3A
Influenza ARAF1;Ccl12;IFNB1;IFIH1;IFNA1;HNRNPUL1;PML;BLB2;IL12B

NUP98 has several biochemical functions, for example, peptide binding, protein binding, structural constituent of nuclear pore. Some of the functions are cooperated with other proteins, some of the functions could acted by NUP98 itself. We selected most functions NUP98 had, and list some proteins which have the same functions with NUP98. You can find most of the proteins on our site.

Function Related Protein
peptide bindingPPIB;THOP1;HCRTR2;AVPR2L;Ctsl;HCRTR1;ADNP;RNPEP;PPYR1
protein bindingKLRB1F;PPP5C;TBKBP1;ETF1;C4orf26;KLRC2;ADAMTSL3;RTN4;NAE1
structural constituent of nuclear poreNUP205;NUP85;NUP153;NUP98;NUP54;NUP107;NUP133;TMEM33;NUP93
transporter activityLBFABP;SV2BA;ABCC6;SLC5A3A;SLC26A3;APODB;CRABP1B;RBP2;HIATL1

NUP98 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NUP98 here. Most of them are supplied by our site. Hope this information will be useful for your research of NUP98.

NXF1; Nup107; hin1l_human; gag-pol; CHM; Nup98; Nup188; Nup214; USP7; HNRNPUL1; QRICH2; MOB1A; APC; uxaC; npm_alk; E2F3; MYC; M

Puthiyaveetil, AG; Heid, B; et al. A NUP98-HOXD13 leukemic fusion gene leads to impaired class switch recombination and antibody production. EXPERIMENTAL HEMATOLOGY 40:622-633(2012).
Chatel, G; Desai, SH; et al. Domain topology of nucleoporin Nup98 within the nuclear pore complex. JOURNAL OF STRUCTURAL BIOLOGY 177:81-89(2012).
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