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NVL

Official Full Name

nuclear VCP-like
Overview

This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) superfamily. Multiple transcript variants encoding different isoforms have been found for this gene. Two encoded proteins, described as major and minor isoforms, have been localized to distinct regions of the nucleus. The largest encoded protein (major isoform) has been localized to the nucleolus and shown to participate in ribosome biosynthesis (PMID: 15469983, 16782053), while the minor isoform has been localized to the nucleoplasmin.
Synonyms

NVL; nuclear VCP-like; nuclear valosin-containing protein-like; Nuclear valosin containing protein like; nuclear VCP like protein; Nuclear VCP like; Nuclear VCP-like protein; NVL_HUMAN; NVLp; OTTHUMP00000035641; OTTHUMP00000216593; OTTHUMP00000216594; OTTHUMP00000216599; OTTHUMP00000216600;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK
Myc|DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NVL-30495TH	Recombinant Human NVL, His-tagged	E.coli	His		Inquiry
Human	NVL-1426H	Recombinant Human NVL, His-tagged	E.coli	His	C-term-351aa	$319 / 25ug
Human	NVL-1237HCL	Recombinant Human NVL cell lysate		N/A		Inquiry
Human	NVL-1972H	Recombinant Human NVL Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	NVL-5695H	Recombinant Human NVL Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	NVL-1855H	Recombinant Human NVL Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	NVL-11012M	Recombinant Mouse NVL Protein	Mammalian Cell	His		Inquiry
Mouse	Nvl-4561M	Recombinant Mouse Nvl Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	NVL-6284M	Recombinant Mouse NVL Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	NVL-6284M-B	Recombinant Mouse NVL Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	NVL-12649Z	Recombinant Zebrafish NVL	Mammalian Cell	His		Inquiry
Chicken	NVL-3546C	Recombinant Chicken NVL	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

NVL involved in several pathways and played different roles in them. We selected most pathways NVL participated on our site, such as Ribosome biogenesis in eukaryotes, which may be useful for your reference. Also, other proteins which involved in the same pathway with NVL were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Ribosome biogenesis in eukaryotes	NHP2L1A;EMG1;DROSHA;CIRH1A;RIOK1;EFTUD1;RBM28;NXF2;POP1

NVL has several biochemical functions, for example, ATP binding, poly(A) RNA binding, preribosome binding. Some of the functions are cooperated with other proteins, some of the functions could acted by NVL itself. We selected most functions NVL had, and list some proteins which have the same functions with NVL. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	FLAD1;TAOK1;PAPSS2;KIF21A;CDK8;EPHB3;ORC4;MOCS3;MYH7
poly(A) RNA binding	TSFM;SNW1;APEX1;CSTF2T;CNOT1;DDX51;CLK3;DHX57;MRPL1
preribosome binding
protein binding	CABLES1;TEAD1;UBE2R2;SIGIRR;RILP;Acr;ZNF398;FUBP3;CDC6

NVL has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with NVL here. Most of them are supplied by our site. Hope this information will be useful for your research of NVL.

HSPB1; UBE2I; CRMP1; OSGEP; TTF2; Srp72; NPM1; UBA1; RPL10; MNDA; CLCN2; RHOA; Cry1; HNRNPU; IFI16; q6t424_human; KIF21A; Rrbp1; Rbm8a; Tmed2