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Nell2

Official Full Name

NEL-like 2 (chicken)
Overview

The protein encoded by this gene is a glycoprotein containing several von Willebrand factor C domains and epidermal growth factor (EGF)-like domains. The encoded protein acts as a homotrimer and is found in the cytoplasm. Several variants encoding a few different isoforms exist, and at least one isoform appears to be a secreted protein. Studies in mouse suggest that this protein plays a role in neural cell growth and differentiation as well as in oncogenesis. [provided by RefSeq, Feb 2009]
Synonyms

NELL2; NEL-like 2 (chicken); NRP2; protein kinase C-binding protein NELL2; NEL-like protein 2; NEL-related protein 2; neural epidermal growth factor-like 2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rhesus Macaque

Source

E.coli
HEK293
HEK293T
In Vitro Cell Free System
Insect Cell
Mammalian Cell
Wheat Germ

Tag

GST
His
His (Fc)
Avi
His|T7
Myc
DDK
Myc|DDK
N/A
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	NELL2-492H	Recombinant Human NELL2 Protein, His-tagged	Insect Cell	His		Inquiry
Human	NELL2-29300TH	Recombinant Human NELL2	Wheat Germ	N/A	816 amino acids	Inquiry
Human	NELL2-1262H	Recombinant Human NELL2, GST-tagged	E.coli	GST	443-740aa	$319 / 25ug
Human	NELL2-29302TH	Recombinant Human NELL2	Wheat Germ	N/A	100 amino acids	Inquiry
Human	NELL2-468HCL	Recombinant Human NELL2 cell lysate	Insect Cell	N/A		Inquiry
Human	NELL2-337HF	Recombinant Full Length Human NELL2 Protein	In Vitro Cell Free System		816 amino acids	Inquiry
Human	NELL2-1915H	Recombinant Human NELL2 protein, His & T7-tagged	E.coli	His/T7	Pro64~Lys331 (Accession # Q99435)	Inquiry
Human	NELL2-758H	Recombinant Human NELL2 Protein, MYC/DDK-tagged	HEK293	Myc/DDK		Inquiry
Human	NELL2-6562H	Recombinant Human NELL2 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	NELL2-4683H	Recombinant Human NELL2 Protein (Pro64-Lys331), N-His tagged	E.coli	N-His	Pro64-Lys331	Inquiry
Mouse	Nell2-394M	Recombinant Mouse NEL-like 2 (Chicken), His-tagged	E.coli	His		Inquiry
Mouse	Nell2-4374M	Recombinant Mouse Nell2 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Rhesus Macaque	NELL2-3001R	Recombinant Rhesus monkey NELL2 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	NELL2-2820R	Recombinant Rhesus Macaque NELL2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rhesus Macaque	NELL2-2820R-B	Recombinant Rhesus Macaque NELL2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Chicken	NELL2-2441C	Recombinant Chicken NELL2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
Nell2 Related Research Area

Nell2 involved in several pathways and played different roles in them. We selected most pathways Nell2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with Nell2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

Nell2 has several biochemical functions, for example, calcium ion binding, heparin binding, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by Nell2 itself. We selected most functions Nell2 had, and list some proteins which have the same functions with Nell2. You can find most of the proteins on our site.

Function	Related Protein
calcium ion binding	EFCAB12;GPD2;EHD4;PCDH2G3;PCDH2G17;FKBP14;MICU1;AASS;PCDH2AB10
heparin binding	TGFBR3;NRP1A;FGF10;Epy;SAA1;LIPG;FGF14;ZFP207;NAV2
identical protein binding	CLDNG;NDC80;TTN;NEFL;ST13;BNIP3L;NME1;ATL2;CHAF1A
protein binding	ITGA1;PARD3;SGK1;KCNH2;ALPL;NAA10;MTF1;TOR1B;GNB1
protein kinase C binding	HDAC7A;CASQ2;PAWR;MARCKS;FEZ1;SDC4;PRKCSH;PKP2;PRKCB

Nell2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Nell2 here. Most of them are supplied by our site. Hope this information will be useful for your research of Nell2.

GFI1B; CACNA1A; ATXN7; PRKAR1A; ATN1; ompA4; q8ckw7_yerpe; mdtB; q9wmx2-pro_0000037548

Neuronal Lineage Markers