OAZ2
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Official Full Name
ornithine decarboxylase antizyme 2
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Overview
Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. The antizyme encoded by this gene inhibits ornithine decarboxylase but does not accelerate its degradation. -
Synonyms
OAZ2; ornithine decarboxylase antizyme 2; ODC-Az 2; AZ2;
- Recombinant Proteins
- Protein Pre-coupled Magnetic Beads
- Chicken
- Cynomolgus Monkey
- Human
- Mouse
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- Involved Pathway
- Protein Function
- Interacting Protein
OAZ2 involved in several pathways and played different roles in them. We selected most pathways OAZ2 participated on our site, such as Metabolism, Metabolism of amino acids and derivatives, Metabolism of polyamines, which may be useful for your reference. Also, other proteins which involved in the same pathway with OAZ2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Metabolism | ACSM1;SLC25A27;FAAH2;CYGB1;ARSH;SCO1;PDK3B;ALDH9A1A.2;UGT1B1 |
| Metabolism of amino acids and derivatives | PPM1K;HIBADH;OAZ3;CKBA;DAO;DBH;SLC6A8;LSM1;NAALAD2 |
| Metabolism of polyamines | CKB;SLC6A12;OAZ2;SAT1B;PAOX;AZIN1B;LSM1;SLC6A8;SLC25A15 |
| Regulation of ornithine decarboxylase (ODC) | OAZ1A;AZIN1B;OAZ2;OAZ3;OAZ2B;OAZ1;AZIN1;AZIN1A |
OAZ2 has several biochemical functions, for example, ornithine decarboxylase inhibitor activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OAZ2 itself. We selected most functions OAZ2 had, and list some proteins which have the same functions with OAZ2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| ornithine decarboxylase inhibitor activity | OAZ1A;OAZ2A;OAZ3;OAZ2;OAZ1;OAZ2B |
| protein binding | TLDC2;AGTR1;Casp3;PEPD;PLXNC1;PLEC;KLK15;PPIF;HGF |
OAZ2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OAZ2 here. Most of them are supplied by our site. Hope this information will be useful for your research of OAZ2.
AZIN1; ODC1
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