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OR8A1

Official Full Name

olfactory receptor, family 8, subfamily A, member 1
Overview

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.
Synonyms

OR8A1; olfactory receptor, family 8, subfamily A, member 1; olfactory receptor 8A1; OST025; Olfactory receptor OR11-318; OR11-318;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	OR8A1-3555HCL	Recombinant Human OR8A1 293 Cell Lysate	HEK293	N/A		Inquiry
Homo sapiens (Human)	RFL11767HF	Recombinant Full Length Human Olfactory Receptor 8A1(Or8A1) Protein, His-Tagged	E.coli expression system	His	Full Length (1-326)	Inquiry

Involved Pathway
Protein Function
Interacting Protein

OR8A1 involved in several pathways and played different roles in them. We selected most pathways OR8A1 participated on our site, such as Olfactory transduction, which may be useful for your reference. Also, other proteins which involved in the same pathway with OR8A1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Olfactory transduction	CLCA1;OR5H1;ANO2;OR6Q1;CNGA3;OR1L6;OR2J3;OR6K3;OR5B2

OR8A1 has several biochemical functions, for example, G-protein coupled receptor activity, odorant binding, olfactory receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OR8A1 itself. We selected most functions OR8A1 had, and list some proteins which have the same functions with OR8A1. You can find most of the proteins on our site.

Function	Related Protein
G-protein coupled receptor activity	OR8B8;TAS2R139;MRGPRE;GNRHR3;ADRB3B;OLFR488;OLFR477;GPR162;RGRA
odorant binding	OLFR507;OR10J1;OR6B2;OLFR469;OLFR147;OLFR498;OR13A1;OLFR494;OLFR480
olfactory receptor activity	OR52B6;OR51E2;OR12D2;OR4C13;OLFR1013;OLFR486;OR11A1;OR5H1;OR6B2

OR8A1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OR8A1 here. Most of them are supplied by our site. Hope this information will be useful for your research of OR8A1.