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OSBPL1A

Official Full Name

oxysterol binding protein-like 1A
Overview

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. Transcript variants derived from alternative promoter usage and/or alternative splicing exist; they encode different isoforms.
Synonyms

OSBPL1A; oxysterol binding protein-like 1A; OSBPL1B, oxysterol binding protein like 1B; oxysterol-binding protein-related protein 1; ORP 1; ORP1; OSBP-related protein 1; oxysterol binding protein-like 1B; oxysterol-binding protein-related protein 1 varia;

Type

Cell & Tissue Lysates
Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat

Source

HEK293
HEK293T
Mammalian Cell

Tag

His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	OSBPL1A-3540HCL	Recombinant Human OSBPL1A 293 Cell Lysate	HEK293	N/A	Inquiry
Human	OSBPL1A-3539HCL	Recombinant Human OSBPL1A 293 Cell Lysate	HEK293	N/A	Inquiry
Human	OSBPL1A-3012H	Recombinant Human OSBPL1A Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK	Inquiry
Mouse	Osbpl1a-4608M	Recombinant Mouse Osbpl1a Protein, Myc/DDK-tagged	HEK293T	Myc/DDK	Inquiry
Rat	OSBPL1A-4205R	Recombinant Rat OSBPL1A Protein	Mammalian Cell	His	Inquiry
Rat	OSBPL1A-3867R	Recombinant Rat OSBPL1A Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	OSBPL1A-3867R-B	Recombinant Rat OSBPL1A Protein Pre-coupled Magnetic Beads	HEK293		Inquiry

Involved Pathway
Protein Function
Interacting Protein
OSBPL1A Related Articles

OSBPL1A involved in several pathways and played different roles in them. We selected most pathways OSBPL1A participated on our site, such as Adaptive Immune System, Immune System, MHC class II antigen presentation, which may be useful for your reference. Also, other proteins which involved in the same pathway with OSBPL1A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Adaptive Immune System	TREML2;LILRA2;NRG2A;CTSC;ATG7;MICA;IFI30;SH3RF1;KIF20A
Immune System	SPSB2;EIF4E3;BTR16;ATP6V1G3;BLMH;TREML1;CRCP;DEFA6;MICA
MHC class II antigen presentation	CTSLL;KLC3;MGC174857;KIF3B;KIF15;CTSE;KIF26A;KIF11;OSBPL1A

OSBPL1A has several biochemical functions, for example, cholesterol binding, phospholipid binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OSBPL1A itself. We selected most functions OSBPL1A had, and list some proteins which have the same functions with OSBPL1A. You can find most of the proteins on our site.

Function	Related Protein
cholesterol binding	TSPO;ERLIN2;TSPO2;ANXA6;APOA1;STARD3;OSBPL2;SCP2;OSBPL1A
phospholipid binding	PACSIN1A;PAFAH2;GRK5;NBEAA;SMURF1;LPAR3;ANXA1;NBEA;ANXA5
protein binding	DDX23;FAM151B;TBP;LGALS2;MTAP1B;FGB;ZNF792;SSBP1;PLCG2

OSBPL1A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OSBPL1A here. Most of them are supplied by our site. Hope this information will be useful for your research of OSBPL1A.

GCNT1; Cenpf; Aurkb; Nfya; BCL6; Rab5b; Eea1; KIFAP3; POLG2

Cha, S; Yu, H; et al. Bone Mineral Density-Associated Polymorphisms Are Associated with Obesity-Related Traits in Korean Adults in a Sex-Dependent Manner. PLOS ONE 7:-(2012).

Thorsen, K; Schepeler, T; et al. Tumor-specific usage of alternative transcription start sites in colorectal cancer identified by genome-wide exon array analysis. BMC GENOMICS 12:-(2011).