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OSBPL2

Official Full Name

oxysterol binding protein-like 2
Overview

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although some members contain only the sterol-binding domain. This encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described.
Synonyms

OSBPL2; oxysterol binding protein-like 2; oxysterol binding protein like 2; oxysterol-binding protein-related protein 2; KIAA0772; ORP 2; OSBP-related protein 2; oxysterol-binding protein-like 2; ORP2; ORP-2; MGC4307; MGC8342; FLJ20223;

Type

Recombinant Proteins
Cell & Tissue Lysates

Species

Chicken
Human
Mouse

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	OSBPL2-1469H	Recombinant Human OSBPL2, His-tagged	E.coli	His	128-480aa	$319 / 25ug
Human	OSBPL2-3538HCL	Recombinant Human OSBPL2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	OSBPL2-3516H	Recombinant Human OSBPL2 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	OSBPL2-4605H	Recombinant Human OSBPL2 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	Osbpl2-4609M	Recombinant Mouse Osbpl2 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Chicken	OSBPL2-1827C	Recombinant Chicken OSBPL2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

OSBPL2 involved in several pathways and played different roles in them. We selected most pathways OSBPL2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with OSBPL2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

OSBPL2 has several biochemical functions, for example, cholesterol binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by OSBPL2 itself. We selected most functions OSBPL2 had, and list some proteins which have the same functions with OSBPL2. You can find most of the proteins on our site.

Function	Related Protein
cholesterol binding	OSBPL1A;PROM2;NPC2;APOA4B.2;APOEA;CYP11A1;OSBP2;STAR;ERLIN1
protein binding	FAM101A;SPI1B;GTF2IRD2;TIMM21;RXFP4;SSB;PAQR5;BIRC5;C1orf182

OSBPL2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OSBPL2 here. Most of them are supplied by our site. Hope this information will be useful for your research of OSBPL2.

VAPB; thiF