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OVCA2

Official Full Name

OVCA2 ovarian tumor suppressor candidate 2
Overview

Chromosome 17 is a hotspot for chromosomal aberrations in breast and ovarian cancer. Candidate oncogenes and tumor suppressors located on this chromosome include OVCA1 and OVCA2, p53, BRCA1, HER2/neu and others. OVCA1 and 2 map to a highly conserved region on human chromosome 17p13.3 that is deleted in 80% of ovarian cancers and shows frequent loss of heterozygosity in breast cancers. OVCA1 is induced by BRCA1 and is closely linked to p53, a well-known tumor suppressor gene. The close linkage of OVCA1 and p53 suggests that coordinated loss of the two genes may lead to ovarian, breast and other tumor types
Synonyms

OVCA2; ovarian tumor suppressor candidate 2; ovarian cancer-associated gene 2 protein; candidate tumor suppressor in ovarian cancer 2; ovarian cancer gene-2 protein;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell

Tag

GST
His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	OVCA2-6939H	Recombinant Human Ovarian Tumor Suppressor Candidate 2, His-tagged	E.coli	His	1-227aa	Inquiry
Human	OVCA2-1482H	Recombinant Human OVCA2, GST-tagged	E.coli	GST	1-227aa	$319 / 25ug
Human	OVCA2-3510HCL	Recombinant Human OVCA2 293 Cell Lysate	HEK293	N/A		Inquiry
Human	OVCA2-831H	Recombinant Human OVCA2 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Mouse	OVCA2-12249M	Recombinant Mouse OVCA2 Protein	Mammalian Cell	His		Inquiry
Mouse	OVCA2-6442M	Recombinant Mouse OVCA2 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	OVCA2-6442M-B	Recombinant Mouse OVCA2 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	Ovca2-4630M	Recombinant Mouse Ovca2 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Zebrafish	OVCA2-2743Z	Recombinant Zebrafish OVCA2	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

OVCA2 involved in several pathways and played different roles in them. We selected most pathways OVCA2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with OVCA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein

OVCA2 has several biochemical functions, for example, hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OVCA2 itself. We selected most functions OVCA2 had, and list some proteins which have the same functions with OVCA2. You can find most of the proteins on our site.

Function	Related Protein
hydrolase activity	C9orf156;OTUD4;PPAP2C;MBTPS2;AGBL1;PPP1CBL;CTSJ;INPP5KA;NOTUM1B

OVCA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OVCA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of OVCA2.