Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

PAFAH1B3

  • Official Full Name

    platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)

  • Overview

    This gene encodes an acetylhydrolase that catalyzes the removal of an acetyl group from the glycerol backbone of platelet-activating factor. The encoded enzyme is a subunit of the platelet-activating factor acetylhydrolase isoform 1B complex, which consists of the catalytic beta and gamma subunits and the regulatory alpha subunit. This complex functions in brain development. A translocation between this gene on chromosome 19 and the CDC-like kinase 2 gene on chromosome 1 has been observed, and was associated with mental retardation, ataxia, and atrophy of the brain. Alternatively spliced transcript variants have been described.
  • Synonyms

    PAFAH1B3; platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa); platelet activating factor acetylhydrolase, isoform Ib, gamma subunit (29kD) , platelet activating factor acetylhydrolase, isoform Ib, gamma subunit 29kDa , platelet activating factor acetylhydrolase, isoform Ib, subunit 3 (29kDa); platelet-activating factor acetylhydrolase IB subunit gamma; PAF AH1b alpha 1 subunit; PA1B3_HUMAN; PAF acetylhydrolase 29 kDa subunit; PAF AH 29 kDa subunit; PAF AH subunit gamma; PAF-AH 29 kDa subunit; PAF-AH subunit gamma; PAFAH subunit gamma; PAFAHG; Platelet activating factor acetylhydrolase IB subunit gamma; Platelet activating factor acetylhydrolase isoform Ib gamma subunit (29kD); Platelet activating factor acetylhydrolase isoform Ib gamma subunit 29kDa; Platelet activating factor acetylhydrolase isoform Ib gamma subunit; PAF-AH1b alpha 1 subunit; platelet-activating factor acetylhydrolase, isoform Ib, subunit 3 (29kDa;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PAFAH1B3-28937TH Recombinant Human PAFAH1B3 Wheat Germ N/A 231 amino acids
Human PAFAH1B3-6901H Recombinant Human PAFAH1B3 protein, His & T7-tagged E.coli His/T7 His28~Pro231 (Accession # Q15102)
Human PAFAH1B3-3467HCL Recombinant Human PAFAH1B3 293 Cell Lysate HEK293 N/A
Human PAFAH1B3-5067H Recombinant Human PAFAH1B3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PAFAH1B3-1613H Recombinant Human PAFAH1B3 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PAFAH1B3-359HF Recombinant Full Length Human PAFAH1B3 Protein In Vitro Cell Free System 231 amino acids
Mouse Pafah1b3-6902M Recombinant Mouse Pafah1b3 protein, His & T7-tagged E.coli His/T7 Met1~Ser232 (Accession # Q61205)
Mouse Pafah1b3-4657M Recombinant Mouse Pafah1b3 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PAFAH1B3-4255R Recombinant Rat PAFAH1B3 Protein Mammalian Cell His
Rat PAFAH1B3-3917R Recombinant Rat PAFAH1B3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PAFAH1B3-3917R-B Recombinant Rat PAFAH1B3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque PAFAH1B3-3285R Recombinant Rhesus monkey PAFAH1B3 Protein, His-tagged Mammalian Cell His
Rhesus Macaque PAFAH1B3-3103R-B Recombinant Rhesus Macaque PAFAH1B3 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque PAFAH1B3-3103R Recombinant Rhesus Macaque PAFAH1B3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish PAFAH1B3-11285Z Recombinant Zebrafish PAFAH1B3 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PAFAH1B3 Related Articles

PAFAH1B3 involved in several pathways and played different roles in them. We selected most pathways PAFAH1B3 participated on our site, such as Ether lipid metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PAFAH1B3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Ether lipid metabolismPLA2G6;PPAP2C;PLA2G3;PLA2G2A;ENPP2;PAFAH1B1B;GAL3ST1A;PLA2G5;EPT1
Metabolic pathwaysNME6;DOLK;ADH1;ACLY;MT-ND1;GALNTL1;ALDOC;MAPK1IP1L;PET112L

PAFAH1B3 has several biochemical functions, for example, 1-alkyl-2-acetylglycerophosphocholine esterase activity, identical protein binding, platelet-activating factor acetyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PAFAH1B3 itself. We selected most functions PAFAH1B3 had, and list some proteins which have the same functions with PAFAH1B3. You can find most of the proteins on our site.

Function Related Protein
1-alkyl-2-acetylglycerophosphocholine esterase activityPAFAH2;ASPG;PLA2G7;PAFAH1B3;PAFAH1B2
identical protein bindingCLDN4;FTL;SDF4;RGMB;ORAI1;OMG;NIF3L1;FKBP8;DNMT3A
platelet-activating factor acetyltransferase activityPAFAH1B3;PAFAH1B2
protein bindingSLC3A1;RAI2;VPS18;NFE2L3;BUC;METTL13;MMP2;C1QTNF9;TSSK6
protein heterodimerization activityTAP1;XBP1;KCNA3;SMC4;IKZF4;TPD52L1;RARA;AHR;ZHX2

PAFAH1B3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAFAH1B3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PAFAH1B3.

Pafah1b1; VCAM1; LNX1; GDF9; GAPDH; TP53; XRCC6; GBP2; TERF1; SUMO2; EEF1A1; PAFAH1B2

Warburton, A; Savage, AL; et al. Molecular signatures of mood stabilisers highlight the role of the transcription factor REST/NRSF. JOURNAL OF AFFECTIVE DISORDERS 172:63-73(2015).
Mulvihill, MM; Benjamin, DI; et al. Metabolic Profiling Reveals PAFAH1B3 as a Critical Driver of Breast Cancer Pathogenicity. CHEMISTRY & BIOLOGY 21:831-840(2014).
  • Q&As
  • Reviews

Q&As (0)

Ask a question

Customer Reviews (0)

Write a review

Ask a Question for All PAFAH1B3 Products

Required fields are marked with *

My Review for All PAFAH1B3 Products

Required fields are marked with *

logo

FOLLOW US

Terms and Conditions        Privacy Policy

Copyright © 2024 Creative BioMart. All Rights Reserved.

Contact Us

  • /

Stay Updated on the Latest Bioscience Trends