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PANK1

  • Official Full Name

    pantothenate kinase 1

  • Overview

    coaA (pantothenate kinase) belongs to the prokaryotic pantothenate kinase family. Pantothenate kinase (PanK; CoaA) is the first enzyme in the Coenzyme A biosynthetic pathway. It phophorylates pantothenate (vitamin B5) to form 4'-phosphopantothenate. Regulation of pantothenate kinase activity by feedback inhibition is the critical factor controlling the intracellular CoA concentration.
  • Synonyms

    PANK1; EC 2.7.1.33 protein; hPanK protein; hPanK1 protein; MGC24596 protein; PANK protein; PANK1a protein; PANK1b protein; pantothenate kinase 1 protein; pantothenate kinase protein; Pantothenic acid kinase 1 protein;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PANK1-33H Recombinant Human PANK1 Protein, GST-tagged Wheat Germ GST 1 a.a. - 373 a.a.
Human PANK1-1520H Recombinant Human PANK1, GST-tagged E.coli GST C-term-137aa
Human PANK1-32H Recombinant Human PANK1, MYC/DDK-tagged HEK293 Myc/DDK
Human PANK1-34H Recombinant Human PANK1 Protein, GST-tagged Wheat Germ GST 310 a.a. - 409 a.a.
Human PANK1-1278HCL Recombinant Human PANK1 cell lysate N/A
Human PANK1-3402H Recombinant Human PANK1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PANK1-1895H Recombinant Human PANK1 Protein, His&GST-tagged E.coli N-His&GST Pro234-Lys593
Human PANK1-1541HF Recombinant Full Length Human PANK1 Protein, GST-tagged In Vitro Cell Free System GST 373 amino acids
Mouse PANK1-12333M Recombinant Mouse PANK1 Protein Mammalian Cell His
Mouse Pank1-8019M Recombinant Mouse Pank1 protein, His & T7-tagged E.coli His/T7 Glu298~Arg500 (Accession # Q8K4K6)
Mouse Pank1-4668M Recombinant Mouse Pank1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse PANK1-6484M Recombinant Mouse PANK1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PANK1-6484M-B Recombinant Mouse PANK1 Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PANK1 Related Articles

PANK1 involved in several pathways and played different roles in them. We selected most pathways PANK1 participated on our site, such as Pantothenate and CoA biosynthesis, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PANK1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Pantothenate and CoA biosynthesisPPCS;BCAT1;AASDHPPT;PANK1B;ENPP1;VNN2;BCAT2;ENPP3;DPYS
Metabolic pathwaysSDHA;OAT;QDPR;GLUD2;PIGH;GCDHB;CBR3;CAD;CYP2R1

PANK1 has several biochemical functions, for example, ATP binding, pantothenate kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PANK1 itself. We selected most functions PANK1 had, and list some proteins which have the same functions with PANK1. You can find most of the proteins on our site.

Function Related Protein
ATP bindingMYH7;SRPK2;DYNC2H1;PRKACAB;NRBP2;ATP13A5;HSP70L;HUNK;TSSK5
pantothenate kinase activityPANK3;PANK4;PANK1B;PANK1;PANK2

PANK1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PANK1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PANK1.

YWHAZ

Deperas-Kaminska, M; Bajinskis, A; et al. RADIATION-INDUCED CHANGES IN LEVELS OF SELECTED PROTEINS IN PERIPHERAL BLOOD SERUM OF BREAST CANCER PATIENTS AS A POTENTIAL TRIAGE BIODOSIMETER FOR LARGE-SCALE RADIOLOGICAL EMERGENCIES. HEALTH PHYSICS 107:555-563(2014).
de Villiers, M; Barnard, L; et al. Variation in pantothenate kinase type determines the pantothenamide mode of action and impacts on coenzyme A salvage biosynthesis. FEBS JOURNAL 281:4731-4753(2014).
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