Pcolce
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Official Full Name
procollagen C-endopeptidase enhancer
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Overview
Fibrillar collagen types I-III are synthesized as precursor molecules known as procollagens. These precursors contain amino- and carboxyl-terminal peptide extensions known as N- and C-propeptides, respectively, which are cleaved, upon secretion of procollagen from the cell, to yield the mature triple helical, highly structured fibrils. This gene encodes a glycoprotein which binds and drives the enzymatic cleavage of type I procollagen and heightens C-proteinase activity. [provided by RefSeq, Jul 2008] -
Synonyms
PCOLCE; procollagen C-endopeptidase enhancer; PCPE; PCPE1; PCPE-1; procollagen C-endopeptidase enhancer 1; procollagen C-proteinase enhancer 1; procollagen COOH-terminal proteinase enhancer 1; type 1 procollagen C-proteinase enhancer protein; type I procollagen COOH-terminal proteinase enhancer; procollagen, type 1, COOH-terminal proteinase enhancer;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- His
- His (Fc)
- Avi
- His|S
- Myc
- DDK
- N/A
- N
- T7
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | PCOLCE-30795TH | Recombinant Human PCOLCE | Wheat Germ | N/A | 449 amino acids | |
Human | PCOLCE-1580H | Recombinant Human PCOLCE, His-tagged | E.coli | His | 169-449aa | |
Human | PCOLCE-372H | Recombinant Human PCOLCE | Mammalian Cell | His | ||
Human | PCOLCE-838H | Recombinant Human PCOLCE, T7-tagged | E.coli | T7 | ||
Human | PCOLCE-6802H | Recombinant Human PCOLCE protein, His & S-tagged | E.coli | His/S | Ala315~Cys437 (Accession # Q15113) | |
Human | PCOLCE-3375HCL | Recombinant Human PCOLCE 293 Cell Lysate | HEK293 | N/A | ||
Human | PCOLCE-6411H | Recombinant Human PCOLCE Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Human | PCOLCE-3806H | Recombinant Human PCOLCE Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Human | PCOLCE-3806H-B | Recombinant Human PCOLCE Protein Pre-coupled Magnetic Beads | HEK293 | |||
Human | PCOLCE-4819H | Recombinant Human PCOLCE Protein (Ala315-Cys437), N-His tagged | E.coli | N-His | Ala315-Cys437 | |
Human | PCOLCE-363HF | Recombinant Full Length Human PCOLCE Protein | In Vitro Cell Free System | 449 amino acids | ||
Mouse | Pcolce-6803M | Recombinant Mouse Pcolce protein, His-tagged | E.coli | His | Cys36~Ala468 (Accession # Q61398) | |
Mouse | Pcolce-4717M | Recombinant Mouse Pcolce Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Rat | PCOLCE-4304R | Recombinant Rat PCOLCE Protein | Mammalian Cell | His | ||
Rat | PCOLCE-3966R | Recombinant Rat PCOLCE Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rat | PCOLCE-3966R-B | Recombinant Rat PCOLCE Protein Pre-coupled Magnetic Beads | HEK293 |
- Involved Pathway
- Protein Function
- Interacting Protein
- Pcolce Related Articles
- Pcolce Related Research Area
Pcolce involved in several pathways and played different roles in them. We selected most pathways Pcolce participated on our site, such as Assembly of collagen fibrils and other multimeric structures, Collagen biosynthesis and modifying enzymes, Collagen formation, which may be useful for your reference. Also, other proteins which involved in the same pathway with Pcolce were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Assembly of collagen fibrils and other multimeric structures | COL2A1;CTSS;CTSL1;MMP13;LOXL1;COL4A5;CD151;ABHD1;CTSL2 |
Collagen biosynthesis and modifying enzymes | SERPINH1B;PCOLCEA;COL10A1;COL6A2;COL5A1;COL4A4;COL6A3;ADAMTS3;COL28A1 |
Collagen formation | CTSB;PCOLCE;LOXL4;COL4A3;COL8A1A;LEPRE1;COL9A1B;PCOLCEA;COL13A1 |
Crosslinking of collagen fibrils | BMP1B;TLL1;LOX;PCOLCE;LOXL1;BMP1;LOXL2;TLL2;ABHD1 |
Extracellular matrix organization | CEACAM8;LEPREL1;MMP20;CAPNS1;COL5A3A;COL16A1;COL19A1;COL17A1A;BGNA |
Pcolce has several biochemical functions, for example, collagen binding, heparin binding, peptidase activator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by Pcolce itself. We selected most functions Pcolce had, and list some proteins which have the same functions with Pcolce. You can find most of the proteins on our site.
Function | Related Protein |
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collagen binding | SMAD7;PDGFA;DDR2;ITGA2;ADAM9;PODN;DDR1;LUM;MTAP1A |
heparin binding | RSPO2;CCL8;WISP1B;WISP1A;APOH;APOA5;APOB;FGF1;ELANE |
peptidase activator activity | PINK1;PSME4;PCOLCE;APP;FN1;CAV1;PCOLCE2;MMP14;FBLN1 |
protein binding | PVRL1;HP;DIXDC1;BEX2;TRADD;BCL2L11;IGFL1;CHDH;SSTR3 |
Pcolce has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with Pcolce here. Most of them are supplied by our site. Hope this information will be useful for your research of Pcolce.
COL18A1; lm-111_human_complex; collagen_vi_human; APP; THBS1; hyaluronan; chondroitin_sulfate; dermatan_sulfate; heparin; heparan_sulfate; collagen_iv_human-3_complex
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