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PDIA2

  • Official Full Name

    protein disulfide isomerase family A, member 2

  • Overview

    Protein disulfide isomerases (EC 5.3.4.1), such as PDIP, are endoplasmic reticulum (ER) resident proteins that catalyze;protein folding and thiol-disulfide interchange reactions (Desilva et al., 1996 (PubMed 8561901)).
  • Synonyms

    PDIA2; protein disulfide isomerase family A, member 2; PDIP, protein disulfide isomerase, pancreatic , protein disulfide isomerase associated 2; protein disulfide-isomerase A2; PDA2; PDI; PDIR; protein disulfide isomerase A2; Rho GDP dissociation inhibi;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Human
  • Mamanlian cells
  • Mammalian Cell
  • Yeast
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|T7
  • SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PDIA2-1814H Recombinant Human Protein Disulfide Isomerase Family A, Member 2, His-tagged Human His
Human PDIA2-673H Recombinant Human PDIA2, MYC/DDK-tagged HEK293 Myc/DDK
Human PDIA2-672H Recombinant Human Protein Disulfide Isomerase Family A, Member 2 E.coli N/A
Human PDIA2-1660H Recombinant Human Protein Disulfide Isomerase Family A, Member 2 E.coli N/A
Human PDIA2-7047H Recombinant Human PDIA2 protein, His & T7-tagged E.coli His/T7 Leu309~Leu525 (Accession # Q13087)
Human PDIA2-2676H Recombinant Human PDIA2 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PDIA2-8515HFL Recombinant Full Length Human PDIA2, Flag-tagged Mamanlian cells Flag
Human PDIA2-5096H Recombinant Human PDIA2 Protein (Leu309-Leu525), N-His tagged E.coli N-His Leu309-Leu525
Mouse PDIA2-12576M Recombinant Mouse PDIA2 Protein Mammalian Cell His
Mouse Pdia2-28M Recombinant Mouse Pdia2 protein, His-tagged E.coli His
Mouse Pdia2-3327M Recombinant Mouse Pdia2 protein, His-SUMO-tagged E.coli His-SUMO 21-527aa
Mouse PDIA2-6601M Recombinant Mouse PDIA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PDIA2-1481M Recombinant Mouse PDIA2 Protein (21-527 aa), His-tagged Yeast His 21-527 aa
Mouse Pdia2-4763M Recombinant Mouse Pdia2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse PDIA2-6601M-B Recombinant Mouse PDIA2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque PDIA2-3357R Recombinant Rhesus monkey PDIA2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque PDIA2-3175R Recombinant Rhesus Macaque PDIA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PDIA2-3175R-B Recombinant Rhesus Macaque PDIA2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PDIA2-11277Z Recombinant Zebrafish PDIA2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PDIA2 Related Articles

PDIA2 involved in several pathways and played different roles in them. We selected most pathways PDIA2 participated on our site, such as Statin Pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PDIA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Statin PathwayAPOC4;APOC1;PDIA2;CETP

PDIA2 has several biochemical functions, for example, disulfide oxidoreductase activity, contributes_to peptidyl-proline 4-dioxygenase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PDIA2 itself. We selected most functions PDIA2 had, and list some proteins which have the same functions with PDIA2. You can find most of the proteins on our site.

Function Related Protein
disulfide oxidoreductase activityPDIA3;PDIA2;TXNL1;GRX2;COIL;TMX1;TXN;DNAJC10
contributes_to peptidyl-proline 4-dioxygenase activity
protein bindingSIRT2;ASPH;VPS41;IL6R;CHD1;GATA6;PEAK1;RPA3;SCNN1B
protein disulfide isomerase activityPDIA2;PDIA6;PDIP5;TMX1;QSOX1;TMX3;TXNDC5;PIGK;ITGB3
steroid bindingPAQR7A;ESRRG;PGRMC1;PAQR7B;ESRRGB;ESRRA;CYP21A2;AKR1D1;GPR30

PDIA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PDIA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PDIA2.

ABL1; FYN; SRC; NCK1; PLCG1; PIK3R1; CRK; GRB2; P4HB; CALR

Mizuuchi, Y; Aishima, S; et al. Anterior gradient 2 downregulation in a subset of pancreatic ductal adenocarcinoma is a prognostic factor indicative of epithelial-mesenchymal transition. LABORATORY INVESTIGATION 95:193-206(2015).
Fijak, M; Zeller, T; et al. Autoantibodies against protein disulfide isomerase ER-60 are a diagnostic marker for low-grade testicular inflammation. HUMAN REPRODUCTION 29:2382-2392(2014).
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