PAEP
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Official Full Name
progestagen-associated endometrial protein
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Overview
This gene is a member of the kernel lipocalin superfamily whose members share relatively low sequence similarity but have highly conserved exon/intron structure and three-dimensional protein folding. Most lipocalins are clustered on the long arm of chromosome 9. The encoded glycoprotein has been previously referred to as pregnancy-associated endometrial alpha-2-globulin, placental protein 14, and glycodelin, but has been officially named progestagen-associated endometrial protein. Three distinct forms, with identical protein backbones but different glycosylation profiles, are found in amniotic fluid, follicular fluid and seminal plasma of the reproductive system. These glycoproteins have distinct and essential roles in regulating a uterine environment suitable for pregnancy and in the timing and occurrence of the appropriate sequence of events in the fertilization process. A number of alternatively spliced transcript variants have been observed at this locus, but the full-length nature of only two, each encoding the same protein, has been determined. -
Synonyms
PAEP; progestagen-associated endometrial protein; glycodelin; alpha uterine protein; GD; GdA; GdF; GdS; glycodelin A; glycodelin F; glycodelin S; MGC138509; MGC142288; PAEG; PEP; PP14; PP14 protein (placental protein 14); pregnancy associated endometrial;
- Recombinant Proteins
- Cell & Tissue Lysates
- Native Proteins
- Protein Pre-coupled Magnetic Beads
- Bovine
- Human
- Pig
- Rhesus Macaque
- E.coli
- HEK293
- HEK293T
- In Vitro Cell Free System
- Mammalian Cell
- Milk
- Wheat Germ
- His
- His (Fc)
- Avi
- Myc
- His|T7
- DDK
- N/A
- N
- GST
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | PAEP-31025TH | Recombinant Human PAEP | Wheat Germ | N/A | 180 amino acids | |
Human | PAEP-7563H | Recombinant Human PAEP, His-tagged | E.coli | His | 19-180aa | |
Human | PAEP-3470HCL | Recombinant Human PAEP 293 Cell Lysate | HEK293 | N/A | ||
Human | PAEP-3469HCL | Recombinant Human PAEP 293 Cell Lysate | HEK293 | N/A | ||
Human | PAEP-6549H | Recombinant Human PAEP Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Myc/DDK | ||
Human | PAEP-1893H | Recombinant Human PAEP Protein, His&GST-tagged | E.coli | N-His&GST | Met19-Phe158 | |
Human | PAEP-5048H | Recombinant Human PAEP protein, His&Myc-tagged | HEK293 | His&Myc | 19-180aa | |
Human | PAEP-354HF | Recombinant Full Length Human PAEP Protein | In Vitro Cell Free System | 180 amino acids | ||
Human | PAEP-4788H | Recombinant Human PAEP Protein (Met19-Phe158), N-GST tagged | E.coli | N-GST | Met19-Phe158 | |
Bovine | PAEP-04B | Native Bovine PAEP Protein | Milk | |||
Bovine | PAEP-0034B | Recombinant Bovine PAEP Protein (Lys17-Ile178), N-His-tagged | E.coli | N-His | Lys17-Ile178 | |
Rhesus Macaque | PAEP-3282R | Recombinant Rhesus monkey PAEP Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | PAEP-3100R-B | Recombinant Rhesus Macaque PAEP Protein Pre-coupled Magnetic Beads | HEK293 | |||
Rhesus Macaque | PAEP-3100R | Recombinant Rhesus Macaque PAEP Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Pig | PAEP-5750P | Recombinant Pig PAEP protein, His & T7-tagged | E.coli | His/T7 | Val19~Val178 (Accession # P04119) |
- Involved Pathway
- Protein Function
- Interacting Protein
PAEP involved in several pathways and played different roles in them. We selected most pathways PAEP participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PAEP were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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PAEP has several biochemical functions, for example, protein binding, small molecule binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PAEP itself. We selected most functions PAEP had, and list some proteins which have the same functions with PAEP. You can find most of the proteins on our site.
Function | Related Protein |
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protein binding | LPXN;GRAP2;CHMP1B;HSPB11;DOK6;CD59;ADAM1B;MBD4;CD28 |
small molecule binding | PTGDSB;MUP17;PTGDSA;APODA.2;MUP20;LCN2;AMBP;PAEP;LCN15 |
PAEP has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PAEP here. Most of them are supplied by our site. Hope this information will be useful for your research of PAEP.
GRAMD3; XRCC6; UBE2E1; EEF1A1; RIF1; COPS6; IGSF21; ESYT2; SLC25A12; DNAJB5; UBL4A; DDOST; SMAD3; GTF3C2; ZFP91
- Q&As
- Reviews
Q&As (5)
Ask a questionChallenges may include variations in individual PAEP levels and the need for standardized assays for accurate measurements.
Some studies suggest a potential association between low PAEP levels and recurrent pregnancy loss, but more research is needed to establish a definitive link.
PAEP's expression and regulation in the endometrium provide insights into the complex processes involved in implantation and endometrial function.
Elevated or reduced PAEP levels may indicate a risk of complications during pregnancy, such as preeclampsia, allowing for early intervention and management.
Research suggests that manipulating PAEP levels may have therapeutic potential in addressing certain reproductive disorders, though further studies are needed.
Customer Reviews (3)
Write a reviewWith the manufacturer's outstanding technical support, you can be assured that any challenges you encounter will be efficiently addressed.
Its superior quality, combined with the manufacturer's exceptional technical support, provides researchers with the confidence they need to conduct successful experiments and obtain meaningful results.
Researchers who have utilized the PAEP protein laud its reliability and effectiveness in their studies.
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