PEX3
-
Official Full Name
peroxisomal biogenesis factor 3
-
Overview
The product of this gene is involved in peroxisome biosynthesis and integrity. It assembles membrane vesicles before the matrix proteins are translocated. Peroxins (PEXs) are proteins that are essential for the assembly of functional peroxisomes. The peroxisome biogenesis disorders (PBDs) are a group of genetically heterogeneous autosomal recessive, lethal diseases characterized by multiple defects in peroxisome function. The peroxisomal biogenesis disorders are a heterogeneous group with at least 14 complementation groups and with more than 1 phenotype being observed in cases falling into particular complementation groups. Although the clinical features of PBD patients vary, cells from all PBD patients exhibit a defect in the import of one or more classes of peroxisomal matrix proteins into the organelle. Defects in this gene are a cause Zellweger syndrome (ZWS). -
Synonyms
PEX3; peroxisomal biogenesis factor 3; Peroxisomal assembly protein PEX3; TRG18; peroxin-3; transformation-related protein 18;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Bos taurus (Bovine)
- Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster)
- Dictyostelium discoideum (Slime mold)
- Homo sapiens (Human)
- Human
- Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica)
- Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey)
- Mus musculus (Mouse)
- Rat
- Rattus norvegicus (Rat)
- Rhesus Macaque
- Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast)
- Zebrafish
- E.coli
- E.coli expression system
- HEK293
- In Vitro Cell Free System
- Mammalian Cell
- Wheat Germ
- GST
- His
- His (Fc)
- Avi
- Myc
- N/A
| Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| Human | PEX3-1651H | Recombinant Human PEX3, GST-tagged | E.coli | GST | 1-228aa | |
| Human | PEX3-3286HCL | Recombinant Human PEX3 293 Cell Lysate | HEK293 | N/A |
|
|
| Human | PEX3-10H | Recombinant Human PEX3 protein, GST-tagged | Wheat Germ | GST | 373 |
|
| Human | PEX3-11H | Recombinant Human PEX3 protein, GST-tagged | Wheat Germ | GST | 103 |
|
| Human | PEX3-6841HF | Recombinant Full Length Human PEX3 Protein, GST-tagged | In Vitro Cell Free System | GST | 373 amino acids |
|
| Human | PEX3-1222H | Recombinant Human PEX3 protein, His&Myc-tagged | E.coli | His&Myc | 141-373aa |
|
| Rat | PEX3-4384R | Recombinant Rat PEX3 Protein | Mammalian Cell | His |
|
|
| Rat | PEX3-4044R-B | Recombinant Rat PEX3 Protein Pre-coupled Magnetic Beads | HEK293 |
|
||
| Rat | PEX3-4044R | Recombinant Rat PEX3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
|
|
| Bos taurus (Bovine) | RFL5769BF | Recombinant Full Length Bovine Peroxisomal Biogenesis Factor 3(Pex3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-373) |
|
| Cricetulus longicaudatus (Long-tailed dwarf hamster) (Chinese hamster) | RFL29246CF | Recombinant Full Length Cricetulus Longicaudatus Peroxisomal Biogenesis Factor 3(Pex3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-373) |
|
| Dictyostelium discoideum (Slime mold) | RFL6517DF | Recombinant Full Length Dictyostelium Discoideum Peroxisome Biogenesis Factor 3(Pex3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-405) |
|
| Homo sapiens (Human) | RFL14660HF | Recombinant Full Length Human Peroxisomal Biogenesis Factor 3(Pex3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-373) |
|
| Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica) | RFL34641KF | Recombinant Full Length Kluyveromyces Lactis Peroxisomal Biogenesis Factor 3(Pex3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-483) |
|
| Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) | RFL3332MF | Recombinant Full Length Macaca Fascicularis Peroxisomal Biogenesis Factor 3(Pex3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-373) |
|
| Mus musculus (Mouse) | RFL10504MF | Recombinant Full Length Mouse Peroxisomal Biogenesis Factor 3(Pex3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-372) |
|
| Rattus norvegicus (Rat) | RFL587RF | Recombinant Full Length Rat Peroxisomal Biogenesis Factor 3(Pex3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-372) |
|
| Rhesus Macaque | PEX3-3377R | Recombinant Rhesus monkey PEX3 Protein, His-tagged | Mammalian Cell | His |
|
|
| Rhesus Macaque | PEX3-3195R | Recombinant Rhesus Macaque PEX3 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi |
|
|
| Rhesus Macaque | PEX3-3195R-B | Recombinant Rhesus Macaque PEX3 Protein Pre-coupled Magnetic Beads | HEK293 |
|
||
| Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) | RFL3978SF | Recombinant Full Length Saccharomyces Cerevisiae Peroxisomal Biogenesis Factor 3(Pex3) Protein, His-Tagged | E.coli expression system | His | Full Length (1-441) |
|
| Zebrafish | PEX3-10568Z | Recombinant Zebrafish PEX3 | Mammalian Cell | His |
|
- Involved Pathway
- Protein Function
- Interacting Protein
PEX3 involved in several pathways and played different roles in them. We selected most pathways PEX3 participated on our site, such as Peroxisome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PEX3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Peroxisome | HMGCLL1;FAR2;ACSL1B;SCP2;PECR;AGPS;ECI2;IDH1;AGXTA |
PEX3 has several biochemical functions, for example, amino acid transmembrane transporter activity, lipid binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PEX3 itself. We selected most functions PEX3 had, and list some proteins which have the same functions with PEX3. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| amino acid transmembrane transporter activity | SLC36A4;SLC38A6;SLC3A1;SLC7A14;SLC38A4;SLC6A16B;SLC7A13;SLC6A20;SLC38A2 |
| lipid binding | OSBPL6;ACBD5;PSAP;APOA1A;GLTP;PITPNM3;TRIP10;CRABP2B;SH3GLB1 |
| protein binding | DAP3;SH2B1;SMCR7;SCG2;BRPF1;GMNN;GRK6;TKT;U2AF2 |
| protein dimerization activity | POLR2J3;SRFA;TWIST1A;ANO4;POLR1C;HES4;STRA8;NLGN1;NCOA1 |
PEX3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PEX3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PEX3.
PEX19
- Q&As
- Reviews
Ask a Question for All PEX3 Products
Required fields are marked with *
My Review for All PEX3 Products
Required fields are marked with *
