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PFDN1

  • Official Full Name

    prefoldin subunit 1

  • Overview

    This gene encodes a member of the prefoldin beta subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils.
  • Synonyms

    PFDN1; prefoldin subunit 1; prefoldin 1; PFD1; PDF;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • Myc
  • DDK
  • N/A
  • T7
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PFDN1-2855H Recombinant Human Prefoldin Subunit 1, His-tagged E.coli His
Human PFDN1-115H Recombinant Human PFDN1, His tagged E.coli GST
Human PFDN1-8030H Recombinant Human PFDN1 protein, His & T7-tagged E.coli His/T7 Met1~Gln122 (Accession # O60925)
Human PFDN1-192H Recombinant Human PFDN1 protein, T7-tagged E.coli T7
Human PFDN1-2964H Recombinant Human Prefoldin Subunit 1, T7-tagged E.coli T7
Human PFDN1-26969TH Recombinant Human PFDN1, His-tagged E.coli His 109 amino acids
Human PFDN1-3281HCL Recombinant Human PFDN1 293 Cell Lysate HEK293 N/A
Human PFDN1-5167H Recombinant Human PFDN1 protein, GST-tagged E.coli GST 2-122 aa
Human PFDN1-1280H Recombinant Human PFDN1 protein, His-tagged E.coli His Met1-Gln122
Mouse Pfdn1-1009M Recombinant Mouse Pfdn1 Protein, His-tagged E.coli His
Mouse Pfdn1-4806M Recombinant Mouse Pfdn1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rhesus Macaque PFDN1-3379R Recombinant Rhesus monkey PFDN1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque PFDN1-3197R Recombinant Rhesus Macaque PFDN1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PFDN1-3197R-B Recombinant Rhesus Macaque PFDN1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PFDN1-2128Z Recombinant Zebrafish PFDN1 Mammalian Cell His
Chicken PFDN1-4741C Recombinant Chicken PFDN1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PFDN1 involved in several pathways and played different roles in them. We selected most pathways PFDN1 participated on our site, such as Chaperonin-mediated protein folding, Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding, Metabolism of proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with PFDN1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Chaperonin-mediated protein foldingTUBA1B;TUBA3D;FBXL5;NOP56;CCT2;PFDN4;FBXW9;FBXW4;CCT5
Cooperation of Prefoldin and TriC/CCT in actin and tubulin foldingPFDN1;CCT6A;VBP1;PFDN5;PFDN6;PFDN4;TUBA1B;PFDN2;TCP1
Metabolism of proteinsMLEC;SPON2;CST3;MPDU1A;SPON1;TBCD;UBA2;SEC22C;TPP1
Prefoldin mediated transfer of substrate to CCT/TriCPFDN4;CCT7;VBP1;PFDN6;PFDN5;CCT6A;PFDN2;PFDN1
Protein foldingFBXW2;PFDN1;PFDN4;PFDN2;FBXW9;KIFC3;NOP56;ARL2;FBXW5

PFDN1 has several biochemical functions, for example, protein binding involved in protein folding, transcription factor activity, sequence-specific DNA binding, unfolded protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PFDN1 itself. We selected most functions PFDN1 had, and list some proteins which have the same functions with PFDN1. You can find most of the proteins on our site.

Function Related Protein
protein binding involved in protein foldingHSPA1B;PFDN2;PFDN1;CLGN;PDCL3;RIC3;CALR;DNAJB8;CALR3
transcription factor activity, sequence-specific DNA bindingFOXM1;PRDM2;TSC22D2;NKX2-5;ZNF498;FOXA2;RUNX2B;NR3C1;HNF1BB
unfolded protein bindingDNAJA1;DNAJA2;AIP;SPG7;MKKS;NAP1L4;DNAJB13;SSUH2.2;SIL1

PFDN1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PFDN1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PFDN1.

IMMT; GIT1; PRPF4; Tubb4b; IKBKE; RNPS1; MAP3K3; WRAP73; HIP1; NDC80; PLXNB2; ASNA1; SEC31A; EOMES; ALB; RPLP1; NR2F1; CHGA

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