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PGD

  • Official Full Name

    phosphogluconate dehydrogenase

  • Overview

    6-phosphogluconate dehydrogenase is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies.
  • Synonyms

    PGD; phosphogluconate dehydrogenase; 6-phosphogluconate dehydrogenase, decarboxylating; 6PGD;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • Strep
  • Myc
  • DDK
  • MYC
  • N/A
  • No tag
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PGD-393H Active Recombinant Human PGD Protein, His-tagged E.coli His
Human PGD-2539H Active Recombinant Human PGD protein, His-tagged E.coli His Met1-Ala483
Human PGD-1665H Recombinant Human PGD, GST-tagged E.coli GST 137-483aa
Human PGD-2034H Recombinant Human Phosphogluconate Dehydrogenase, His-tagged E.coli His
Human PGD-3257HCL Recombinant Human PGD 293 Cell Lysate HEK293 N/A
Human PGD-6075H Recombinant Human PGD Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PGD-0259H Recombinant Human PGD Protein (M1-A483), His/Strep tagged E.coli His/Strep M1-A483
Human PGD-5157H Recombinant Human PGD protein, GST-tagged E.coli GST 4-483aa
Human PGD-2048HFL Recombinant Full Length Human PGD Protein, C-Flag-tagged Mammalian cells Flag
Human PGD-4881H Recombinant Human PGD Protein (Met1-Ala483), C-His tagged Mammalian cells C-His Met1-Ala483
Human PGD-1659H-B Recombinant Human PGD Protein Pre-coupled Magnetic Beads HEK293
Human PGD-0258H Recombinant Human PGD Protein (M1-A483), Tag Free E.coli No tag M1-A483
Human PGD-1659H Recombinant Human PGD Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Pgd-459M Recombinant Mouse Pgd Protein, MYC/DDK-tagged HEK293T MYC/DDK
Zebrafish PGD-12623Z Recombinant Zebrafish PGD Mammalian Cell His
Chicken PGD-1448C Recombinant Chicken PGD Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PGD Related Articles

PGD involved in several pathways and played different roles in them. We selected most pathways PGD participated on our site, such as Pentose phosphate pathway, Glutathione metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PGD were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Pentose phosphate pathwayGPIA;GPI1;PFKMB;TKTL1;ALDOAB;TKT;GPI;PRPS1B;PGM1
Glutathione metabolismGSTM2;GGT5A;GSTM5;OPLAH;GGCT;TXNDC12;GPX1A;GSTA5;GPX3
Metabolic pathwaysCSGALNACT2;DPM2;GLUD1;POC1BL;FBP1B;BST1;NANS;AOC2;B3GNT2B
Carbon metabolismSDHDB;TKTB;PKM2;PFKMB;TKTL1;IDH2;FH1;GPIB;GLUD2

PGD has several biochemical functions, for example, NADP binding, phosphogluconate dehydrogenase (decarboxylating) activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PGD itself. We selected most functions PGD had, and list some proteins which have the same functions with PGD. You can find most of the proteins on our site.

Function Related Protein
NADP bindingNOS1;NOS2;NOS3;HMGCRB;GAPDH;POR;PGD;G6PDX;CAT
phosphogluconate dehydrogenase (decarboxylating) activityHIBADHA;GLYR1;PGD;HIBADH;HIBADHB

PGD has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PGD here. Most of them are supplied by our site. Hope this information will be useful for your research of PGD.

HLA-B; ARF6; IKBKE; USPL1; PRKAB1; TRAF6; LSM8; CDK4; TERF1; GBE1; ssrna_ug; MYC; Magoh; IQCB1; RBM8A

Hodgson, SH; Juma, E; et al. Evaluating controlled human malaria infection in Kenyan adults with varying degrees of prior exposure to Plasmodium falciparum using sporozoites administered by intramuscular injection. FRONTIERS IN MICROBIOLOGY 5:-(2014).
Ius, F; Sommer, W; et al. Early donor-specific antibodies in lung transplantation: Risk factors and impact on survival. JOURNAL OF HEART AND LUNG TRANSPLANTATION 33:1255-1263(2014).
  • Q&As
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