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PGM1

  • Official Full Name

    phosphoglucomutase 1

  • Overview

    The protein encoded by this gene is an isozyme of phosphoglucomutase (PGM) and belongs to the phosphohexose mutase family. There are several PGM isozymes, which are encoded by different genes and catalyze the transfer of phosphate between the 1 and 6 positions of glucose. In most cell types, this PGM isozyme is predominant, representing about 90% of total PGM activity. In red cells, PGM2 is a major isozyme. This gene is highly polymorphic. Mutations in this gene cause glycogen storage disease type 14. Alternativley spliced transcript variants encoding different isoforms have been identified in this gene.
  • Synonyms

    PGM1; phosphoglucomutase 1; phosphoglucomutase-1; Glucose phosphomutase 1; GSD14; OTTHUMP00000010519; OTTHUMP00000010520; PGM 1; PGM1_HUMAN; Phosphoglucomutase1;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • In Vitro Cell Free System
  • Mamanlian cells
  • Mammalian Cell
  • Wheat Germ
  • Flag
  • His
  • His (Fc)
  • Avi
  • His|SUMO
  • Myc
  • DDK
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PGM1-2920H Recombinant Human PGM1 protein, MYC/DDK-tagged HEK293 Myc/DDK
Human PGM1-30003TH Recombinant Human PGM1 Wheat Germ N/A 562 amino acids
Human PGM1-41H Recombinant Human PGM1 protein, His-tagged E.coli His
Human PGM1-3252HCL Recombinant Human PGM1 293 Cell Lysate HEK293 N/A
Human PGM1-716H Recombinant Human PGM1 Protein (1-562 aa), His-SUMO-tagged E.coli His/SUMO 1-562 aa
Human PGM1-370HF Recombinant Full Length Human PGM1 Protein In Vitro Cell Free System 562 amino acids
Human PGM1-9323HFL Recombinant Full Length Human PGM1 protein, Flag-tagged Mamanlian cells Flag
Human PGM1-6579H Recombinant Human PGM1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PGM1-4885H Recombinant Human PGM1 Protein (Gln15-Lys235), N-His tagged E.coli N-His Gln15-Lys235
Human PGM1-4884H Recombinant Human PGM1 Protein (Met1-Lys235), His tagged E.coli His Met1-Lys235
Mouse PGM1-12690M Recombinant Mouse PGM1 Protein Mammalian Cell His
Mouse PGM1-6669M Recombinant Mouse PGM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PGM1-6669M-B Recombinant Mouse PGM1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Pgm1-4825M Recombinant Mouse Pgm1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Cynomolgus Monkey PGM1-788C Recombinant Cynomolgus PGM1 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey PGM1-531C Recombinant Cynomolgus Monkey PGM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey PGM1-531C-B Recombinant Cynomolgus Monkey PGM1 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque PGM1-3392R Recombinant Rhesus monkey PGM1 Protein, His-tagged Mammalian Cell His
Rhesus Macaque PGM1-3210R Recombinant Rhesus Macaque PGM1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PGM1-3210R-B Recombinant Rhesus Macaque PGM1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PGM1-11257Z Recombinant Zebrafish PGM1 Mammalian Cell His
Chicken PGM1-3317C Recombinant Chicken PGM1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PGM1 Related Articles

PGM1 involved in several pathways and played different roles in them. We selected most pathways PGM1 participated on our site, such as Glycolysis / Gluconeogenesis, Pentose phosphate pathway, Galactose metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PGM1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycolysis / GluconeogenesisFBP1B;GM5506;PGAM1A;ALDH3A1;HK1;ACSS2L;PFKP;PFKMA;ADH4
Pentose phosphate pathwaydeoC;PFKMA;FBP1B;TKT;TKTB;PFKP;FBP2;PRPS1;ALDOCA
Galactose metabolismAKR1B1L;PFKMA;HK2;UGP2A;G6PC2;HK3;PGM2;PFKM;PFKMB
Purine metabolismPOLR3K;POLE4;IMPDH1;POLR1E;ATIC;PRPS2;ALLC;RRM1;PDE6A
Starch and sucrose metabolismUGT2B7;UGT1A2;PYGM;HK2;UGT1A3;UGT1A6B;UGT1A6A;UGP2B;AMY2A4
Amino sugar and nucleotide sugar metabolismGMDS;GPI;GALT;NANSA;GALE;HEXA;GPR19;UGP2;CYB5RL
Metabolic pathwaysDHODH;ATP6AP1;CHPF2;MTR;PIGW;GMPPB;AGPAT9L;PHGDH;GLCEA

PGM1 has several biochemical functions, for example, magnesium ion binding, phosphoglucomutase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PGM1 itself. We selected most functions PGM1 had, and list some proteins which have the same functions with PGM1. You can find most of the proteins on our site.

Function Related Protein
magnesium ion bindingPRTFDC1;ATP8A1;MARK1;CLYBL;COMTB;SERPINB1A;ENO3;PRPS1;LATS1
phosphoglucomutase activityPGM1;PGM2;PGM3
protein bindingNIPSNAP3A;AKR1B10;AP4M1;CD2;PACSIN1;CSF2RB;PJA1;OAZ2;WDR24

PGM1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PGM1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PGM1.

TINF2; UBA5; KIF1B; DNAJB6; ENO3; TERF1; dAK1_1; POT1; TERF2IP

Hata, S; Kanomata, N; et al. Cytologic Appearance of Myospherulosis of the Breast Diagnosed by Fine-Needle Aspirates: A Clinical, Cytological and Immunocytochemical Study of 23 Cases. DIAGNOSTIC CYTOPATHOLOGY 39:177-180(2011).
Berbic, M; Schulke, L; et al. Macrophage expression in endometrium of women with and without endometriosis. HUMAN REPRODUCTION 24:325-332(2009).
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