Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

PLA2G1B

  • Official Full Name

    phospholipase A2, group IB (pancreas)

  • Overview

    Phospholipase A2 (EC 3.1.1.4) catalyzes the release of fatty acids from glycero-3-phosphocholines. The best known;varieties are the digestive enzymes secreted as zymogens by the pancreas of mammals. Sequences of pancreatic PLA2;enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to;venom phospholipases of snakes. Other forms of PLA2 have been isolated from brain, liver, lung, spleen, intestine,;macrophages, leukocytes, erythrocytes, inflammatory exudates, chondrocytes, and platelets (Seilhamer et al., 1986;(PubMed 3028739)) .
  • Synonyms

    PLA2G1B; phospholipase A2, group IB (pancreas); PLA2, PLA2A, PPLA2; phospholipase A2; group IB phospholipase A2; phosphatidylcholine 2-acylhydrolase 1B; PLA2; PLA2A; PPLA2; MGC119834; MGC119835;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • E.coli
  • HEK293
  • HEK293T
  • Human Cell
  • Mammalian Cell
  • Mammalian cells
  • C
  • His
  • Myc
  • DDK
  • His (Fc)
  • Avi
  • Myc|DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PLA2G1B-625H Active Recombinant Human PLA2G1B, His-tagged Mammalian cells His
Human PLA2G1B-254H Active Recombinant Human PLA2G1B Protein, His-tagged HEK293 His
Human PLA2G1B-31023TH Recombinant Human PLA2G1B, His-tagged E.coli His
Human PLA2G1B-66H Recombinant Human Phospholipase A2, Group IB (Pancreas), His-tagged E.coli His
Human PLA2G1B-1751H Recombinant Human PLA2G1B, His-tagged E.coli His 1-70aa
Human PLA2G1B-171H Recombinant Human PLA2G1B protein, His-tagged HEK293 His Ala23-Ser148
Human PLA2G1B-2200HCL Recombinant Human PLA2G1B cell lysate Human Cell N/A
Human PLA2G1B-1878H Recombinant Human PLA2G1B Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human PLA2G1B-291H Recombinant Human PLA2G1B Protein, MYC/DDK-tagged, C13 and N15-labeled HEK293 C-Myc/DDK
Human PLA2G1B-3867H Recombinant Human PLA2G1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PLA2G1B-832H Recombinant Human PLA2G1B Protein HEK293 148
Human PLA2G1B-4921H Recombinant Human PLA2G1B Protein (Ala23-Ser148), C-His tagged Mammalian cells C-His Ala23-Ser148
Human PLA2G1B-3867H-B Recombinant Human PLA2G1B Protein Pre-coupled Magnetic Beads HEK293
Human PLA2G1B-4922H Recombinant Human PLA2G1B Protein (Asp16-Ser148), N-His tagged E.coli N-His Asp16-Ser148
Mouse Pla2g1b-1185M Recombinant Mouse Pla2g1b protein(Met1-Cys146), His-tagged HEK293 C-His Met1-Cys146
Mouse PLA2G1B-2033MCL Recombinant Mouse PLA2G1B cell lysate Human Cell N/A
Mouse Pla2g1b-4898M Recombinant Mouse Pla2g1b Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PLA2G1B-4487R Recombinant Rat PLA2G1B Protein Mammalian Cell His
Rat PLA2G1B-4147R Recombinant Rat PLA2G1B Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PLA2G1B-4147R-B Recombinant Rat PLA2G1B Protein Pre-coupled Magnetic Beads HEK293
Chicken PLA2G1B-3919C Recombinant Chicken PLA2G1B Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PLA2G1B Related Articles
  • PLA2G1B Related Research Area

PLA2G1B involved in several pathways and played different roles in them. We selected most pathways PLA2G1B participated on our site, such as Glycerophospholipid metabolism, Ether lipid metabolism, Arachidonic acid metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLA2G1B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycerophospholipid metabolismPNPLA7;PLD1;CHATA;PCYT1AA;CHKA;DGKZ;PLA2G2E;PMT;PLA2G4AA
Ether lipid metabolismPLB1;PLA2G3;UGT8A;PLA2G2A;PAFAH1B1;PAFAH1B3;CEPT1B;GAL3ST1;CEPT1
Arachidonic acid metabolismDPEP2;CYP2C8;FAAH2;PLA2G4AA;PTGIS;CYP2C19;AKR1C3;LTA4H;CYP1B1
Linoleic acid metabolismPLA2G6;CYP2C39;CYP2P9;CYP3A41B;PLA2G5;PLA2G4D;CYP2J5;PLA2G10;PLA2G12A
alpha-Linolenic acid metabolismACOX1;PLA2G5;PLA2G2E;PLA2G4AA;PLA2G6;PLA2G2F;PLA2G3;PLA2G2A;PLA2G1B
Metabolic pathwaysHYAL4;INPP1;NFS1;POLR2J;PIK3C3;CYP17A1;PGAM2;CYP2A4;GLULC
Ras signaling pathwayFGF2;RASGRF2;SHC4;GNB1;PLA2G4A;GNB4;PLD1;GNG10;BCL2L1
Vascular smooth muscle contractionARHGEF1;PLA2G2D;PRKACBA;GNA12A;ADORA2AA;CACNA1SA;RHOA;ROCK2A;CALM1A
Pancreatic secretionITPR3;ATP2B1;AMY2B;ATP1A2;PLCB4;PLCB2;CPA1;PLA2G12B;CELA2B
Fat digestion and absorptionMOGAT3;AGPAT2;PPAP2A;DGAT1;CLPS;Cel;ABCG8;PNLIPRP2;ACAT2

PLA2G1B has several biochemical functions, for example, bile acid binding, calcium ion binding, calcium-dependent phospholipase A2 activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PLA2G1B itself. We selected most functions PLA2G1B had, and list some proteins which have the same functions with PLA2G1B. You can find most of the proteins on our site.

Function Related Protein
bile acid bindingNR1H4;FABP6;STARD5;AKR1C2;PLA2G1B;FABP10A;AKR1C21;FABP1;PYGL
calcium ion bindingSLC25A23;NOTCH1B;FBLN2;MGP;CAPNS1B;BGLAP;EFCAB4A;PVALB7;CALB2
calcium-dependent phospholipase A2 activityPLA2G1B;PLA2G3;PLA2G12A;PLA2G2A;PLA2G4F;PLA2G5;PLA2G4A;PLA2G4B
phospholipase A2 activityPLA2G2D;PLA2G10;PLA2G2F;PLB1;PLA2G12B;PNPLA3;PLA2G4D;RARRES3;PLA2G4A
receptor bindingCSK;CAPRIN2;FGF12A;ECH1;FGF18A;TNFSF9;APOF;FGF6A;POU2F1

PLA2G1B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLA2G1B here. Most of them are supplied by our site. Hope this information will be useful for your research of PLA2G1B.

SOCS2

Karray, A; Ben Ali, Y; et al. Drastic changes in the tissue-specific expression of secreted phospholipases A2 in chicken pulmonary disease. BIOCHIMIE 94:451-460(2012).
Karray, A; Zarai, Z; et al. Kinetic properties of pancreatic and intestinal sPLA2 from chicken and mammals using the monomolecular film technique. JOURNAL OF COLLOID AND INTERFACE SCIENCE 363:620-625(2011).
  • Q&As
  • Reviews

Q&As (5)

Ask a question
How is PLA2G1B involved in cardiovascular diseases? 07/01/2020

PLA2G1B is associated with atherosclerosis and other cardiovascular conditions due to its involvement in lipid metabolism and inflammation.

Are there potential neuroprotective effects of modulating PLA2G1B activity? 12/19/2019

Modulating PLA2G1B activity could be explored for potential neuroprotective effects, given its involvement in processes related to neuroinflammation.

In what diseases is PLA2G1B dysregulation observed? 07/30/2018

Dysregulation of PLA2G1B has been linked to inflammatory disorders, cardiovascular diseases, and certain cancers.

Can PLA2G1B be a therapeutic target for inflammatory conditions? 11/10/2017

Yes, targeting PLA2G1B may be a potential therapeutic strategy for inflammatory diseases, as it plays a role in the production of inflammatory mediators.

Can PLA2G1B inhibitors be used for treating cancer? 09/18/2017

Inhibiting PLA2G1B may be explored as a therapeutic approach in cancer treatment by disrupting lipid metabolism and inhibiting cancer cell proliferation.

Customer Reviews (3)

Write a review
Reviews
03/12/2020

    Its exceptional purity and stability make it an ideal choice for a wide range of applications, ensuring reliable and reproducible results.

    10/16/2017

      The PLA2G1B protein comes highly recommended for its exceptional performance in various research applications.

      01/09/2016

        Its unique characteristics contribute to obtaining clear and detailed structural information, allowing researchers to gain insights into protein interactions and conformational changes.

        Ask a Question for All PLA2G1B Products

        Required fields are marked with *

        My Review for All PLA2G1B Products

        Required fields are marked with *

        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends