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PLCG1

  • Official Full Name

    Phospholipase C, gamma 1

  • Overview

    Phospholipase C, gamma 1, also known as PLCG1, is a protein that in humans is encoded by the PLCG1 gene.
  • Synonyms

    Phospholipase C, gamma 1; PLCG1; NCKAP3; PLC-II; PLC1; PLC148; PLCgamma1;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mamanlian cells
  • Mammalian Cell
  • Mammalian cells
  • Wheat Germ
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • Myc|DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PLCG1-334H Recombinant Human PLCG1 Protein, His-tagged E.coli His Ser1091~Leu1290
Human PLCG1-17H Recombinant Human PLCG1, MYC/DDK-tagged HEK293 Myc/DDK
Human PLCG1-30735TH Recombinant Human PLCG1 Wheat Germ N/A 100 amino acids
Human PLCG1-2145H Recombinant Human PLCG1 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PLCG1-94HFL Recombinant Full Length Human PLCG1 Protein, C-Flag-tagged Mammalian cells Flag
Human PLCG1-301472H Recombinant Human PLCG1 protein, GST-tagged E.coli GST Ala467-His563
Human PLCG1-1703H Recombinant Human PLCG1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PLCG1-1855HFL Recombinant Full Length Human PLCG1, Flag-tagged Mamanlian cells Flag
Human PLCG1-1703H-B Recombinant Human PLCG1 Protein Pre-coupled Magnetic Beads HEK293
Mouse Plcg1-4917M Recombinant Mouse Plcg1 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PLCG1-4505R Recombinant Rat PLCG1 Protein Mammalian Cell His
Rat PLCG1-4165R Recombinant Rat PLCG1 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PLCG1-4165R-B Recombinant Rat PLCG1 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PLCG1-9757Z Recombinant Zebrafish PLCG1 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PLCG1 Related Signal Pathway

PLCG1 involved in several pathways and played different roles in them. We selected most pathways PLCG1 participated on our site, such as Inositol phosphate metabolism, Metabolic pathways, ErbB signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PLCG1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Inositol phosphate metabolismIPPK;PIP4K2A;NUDT4A;INPP4AB;NUDT11;MTMR2;TPI1;MTMR7;PIP5K1C
Metabolic pathwaysPGAM2;PRIM2;CHKB;OAT;PLA2G2E;HSD17B4;DHRS4L2;IPPK;NT5C1B
ErbB signaling pathwaySRC;CAMK2D;KRAS;HBEGFA;HRASA;MAPK8B;SOS1;MAPK8;PRKCB
Ras signaling pathwayMAPK1;PLCG2;CALM2;RAF1;HRAS;PIK3CB;FGF16;PLA2G6;CDC42
Rap signaling pathwayRAC2;KIT;HRAS;AKT1;ITGA2B;GRIN2B;PIK3R2;PLCB1;HGF
Calcium signaling pathwayAVPR1A;TBXA2R;ADRA1D;CALML5;PPIFB;TACR1;PRKACAB;ADRA1BB;GRPR
NF-kappa B signaling pathwayCCL21;ZAP70;TNFRSF13C;IRAK1;Bcl2a1b;CD40;TRAF2;IL1R1;SYK
HIF- signaling pathwayGM5506;MAP2K2;TEK;EPO;NOX1;MKNK1;TLR4;INS1;CAMK2G
Phosphatidylinositol signaling systemCALM4;INPP5K;PLCB1;PLCD1A;PIP4K2C;PIP5K2;IMPAD1;INPP4B;MTMR2
Phospholipase D signaling pathwayCYTH1;SHC3;RALGDS;PPAP2B;CYTH3;PLA2G4C;PPAP2C;Kitl;Adcy4
VEGF signaling pathwayVEGFA;PRKCA;PTGS2;HRAS;PIK3R3B;PTK2;RAC3A;MAPK11;RAC1
Natural killer cell mediated cytotoxicityMAP2K2;IFNA2;NCR3;RAET1G;IFNA14;TNFRSF10D;MAPK3;PLCG1;BID
T cell receptor signaling pathwayPDPK1;PRKCQ;MAP2K7;CD28;CD3D;RELA;MUC1;CBLC;Il2
Fc epsilon RI signaling pathwayFCER1G;PDPK1;HRAS;MAP2K3;RAC3;PIK3R3;IL5;PRKCA;MAP2K4
Fc gamma R-mediated phagocytosisPIK3R2;VAV3;PPAP2B;FCGR1;CDC42;PLA2G4A;PIK3CD;PLD2;ARPC5L
Leukocyte transendothelial migrationROCK2;ITGB2;TXK;CYBB;CTNNA3;MYL12A;ROCK1;PIK3R2;THY1
Neurotrophin signaling pathwayMAPK3;PDPK1;PIK3CA;CAMK2A;AKT1;CALM3;IRS1;CAMK2D;CAMK2B
Inflammatory mediator regulation of TRP channelsMAPK8;MAPK10;KLK1B4;PLA2G4F;CYP2C70;CALML3;PIK3CG;CYP2C39;TRPM8
Thyroid hormone signaling pathwayPLCB4;CCND1;SIN3A;HDAC3;ACTB;TP53;KAT2B;PFKP;PLCB1
Vibrio cholerae infectionATP6V0E1;ATP6V1D;ATP6V1C2;ATP6V1B2;ATP6V1G1;ATP6V1C1;TJP2;MUC2;ATP6V0A4
Epithelial cell signaling in Helicobacter pylori infectionCCL5;ATP6V0A4;CXCR2;TJP1;MAPK12;MAPK13;PLCG2;TCIRG1;NFKBIA
Epstein-Barr virus infectionNFKB2;EIF2AK1;CD19;HDAC4;HDAC2;HLA-DRB3;EP300;CCNA2;MAPK8
Pathways in cancerGNAI3;BIRC2;RHOA;MSH2;APC2;MAPK8;WNT7A;BIRC8;WNT10B
Proteoglycans in cancerNRAS;PRKACB;ITGA2;CBLC;FLNC;RAC1;ERBB3;ERBB4;HPSE2
MicroRNAs in cancerNOTCH3;HNRNPK;ZEB2;PRKCB;TP53;MTOR;TNC;DNMT3A;STMN1
GliomaPRKCB;KRAS;MAP2K2;TGFA;PIK3CD;AKT2;SHC4;AKT1;PTEN
Non-small cell lung cancerTRP53;RB1;PIK3R3;MAP2K1;PIK3R5;PLCG1;BAD;AKT1;PIK3CB
Choline metabolism in cancerMAPK10;PLA2G4F;PLA2G4D;RALGDS;RAC3;SLC44A1;PDGFA;PDGFC;HIF1A

PLCG1 has several biochemical functions, for example, calcium ion binding, glutamate receptor binding, neurotrophin TRKA receptor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PLCG1 itself. We selected most functions PLCG1 had, and list some proteins which have the same functions with PLCG1. You can find most of the proteins on our site.

Function Related Protein
calcium ion bindingCALN1;ANXA13;PKD2L2;FBLN7;PCDH1A3;HPCA;LPCAT1;PRRG4;F9
glutamate receptor bindingGRIN1;PLCG1;CAMK2A;SYNDIG1;GRIN2A
neurotrophin TRKA receptor bindingPLCG1;FRS2;NGFR;EFNA5;GRB2;SHC1;PIK3R1
phosphatidylinositol phospholipase C activityEDNRA;C3AR1;PLCB4;CCR1;PLCG2;PLCD1;PLCZ1;CCL5;PLCE1
phospholipase C activityPLCB3;PDIA3;PLCG1;PLCB4;ADORA1;PLCL1;PLCG2;PLCB2;PLCH2
protein bindingUSP17L2;CDKN2A;JAK1;PDZD11;KRTAP23-1;PI4KA;RCN3;ARFRP1;IL17RE
protein kinase bindingITGB2;PPP1R12C;VDAC1;HDAC7;HCLS1;MAVS;CAV2;CCNK;CSPG4
receptor signaling protein activityRAF1A;FCGR1A;NSMAF;DAXX;NCR1;RGS14;ARF1;ARAF;KLK1B4
receptor tyrosine kinase bindingPTPN14;HYAL2;ANXA5;NCK1;PTPN11;ANGPT1;MYOC;ZFP259;ZNF259

PLCG1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PLCG1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PLCG1.

EGFR; INSR; FGFR1

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