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PMPCB

  • Official Full Name

    peptidase (mitochondrial processing) beta

  • Overview

    This gene is a member of the peptidase M16 family and encodes a protein with a zinc-binding motif. This protein is located in the mitochondrial matrix and catalyzes the cleavage of the leader peptides of precursor proteins newly imported into the mitochondria, though it only functions as part of a heterodimeric complex.
  • Synonyms

    PMPCB; peptidase (mitochondrial processing) beta; mitochondrial-processing peptidase subunit beta; MPPB; MPPP52; Beta MPP; BetaMPP; Mitochondrial processing peptidase subunit beta; MPP11; P 52; P52; Peptidase mitichondrial processing beta; mitochondrial processing peptidase beta subunit; P-52; Beta-MPP;

  • Recombinant Proteins
  • Native Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • Mammalian cells
  • DDK
  • Flag
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • Myc|DDK
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PMPCB-2146H Recombinant Human PMPCB Protein, MYC/DDK-tagged HEK293 Myc/DDK
Human PMPCB-281H Recombinant Human PMPCB, GST-tagged GST
Human PMPCB-282H Recombinant Human PMPCB, GST-tagged GST
Human PMPCB-1811H Recombinant Human PMPCB, GST-tagged E.coli GST 1-349aa
Human PMPCB-284H Native Human PMPCB, DDK-tagged HEK293T DDK
Human PMPCB-1719H Recombinant Human PMPCB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PMPCB-899HFL Recombinant Full Length Human PMPCB Protein, C-Flag-tagged Mammalian cells Flag
Human PMPCB-1719H-B Recombinant Human PMPCB Protein Pre-coupled Magnetic Beads HEK293
Mouse PMPCB-13019M Recombinant Mouse PMPCB Protein Mammalian Cell His
Mouse PMPCB-6877M Recombinant Mouse PMPCB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Pmpcb-4959M Recombinant Mouse Pmpcb Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse PMPCB-6877M-B Recombinant Mouse PMPCB Protein Pre-coupled Magnetic Beads HEK293
Rat PMPCB-4543R Recombinant Rat PMPCB Protein Mammalian Cell His
Rat PMPCB-4203R-B Recombinant Rat PMPCB Protein Pre-coupled Magnetic Beads HEK293
Rat PMPCB-4203R Recombinant Rat PMPCB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey PMPCB-796C Recombinant Cynomolgus PMPCB Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey PMPCB-539C Recombinant Cynomolgus Monkey PMPCB Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Cynomolgus Monkey PMPCB-539C-B Recombinant Cynomolgus Monkey PMPCB Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PMPCB-2055Z Recombinant Zebrafish PMPCB Mammalian Cell His
Chicken PMPCB-4328C Recombinant Chicken PMPCB Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PMPCB Related Articles

PMPCB involved in several pathways and played different roles in them. We selected most pathways PMPCB participated on our site, such as Metabolism of proteins, Mitochondrial protein import, which may be useful for your reference. Also, other proteins which involved in the same pathway with PMPCB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Metabolism of proteinsASNA1;PFDN2;F9B;YY2;NEU3;MLEC;ATP6AP2;LMCD1;TIMM8A
Mitochondrial protein importDNAJC19;GFER;TIMM22;HSCB;TIMM17A;TOMM40;SLC25A13;PMPCB;TIMM17B

PMPCB has several biochemical functions, for example, metalloendopeptidase activity, zinc ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PMPCB itself. We selected most functions PMPCB had, and list some proteins which have the same functions with PMPCB. You can find most of the proteins on our site.

Function Related Protein
metalloendopeptidase activityADAMTS15A;ADAMDEC1;TLL2;MMP17;Adamts19;MMP7;ADAM10A;MMP23B;C6AST4
zinc ion bindingEWSR1B;RANBP2;FBXO30B;ADAM8;NR1D1;SIAH1;NR4A2B;MT1E;POLR2K

PMPCB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PMPCB here. Most of them are supplied by our site. Hope this information will be useful for your research of PMPCB.

MARK3; ICT1; CLPP; SIRT4

McCord, LA; Liang, WGG; et al. Conformational states and recognition of amyloidogenic peptides of human insulin-degrading enzyme. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110:13827-13832(2013).
Wattiaux, R; Coninck, SWD; et al. Lysosornes and Fas-mediated liver cell death. BIOCHEMICAL JOURNAL 403:89-95(2007).
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