POLR2D
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Official Full Name
polymerase (RNA) II (DNA directed) polypeptide D
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Overview
This gene encodes the fourth largest subunit of RNA polymerase II, the polymerase responsible for synthesizing messenger RNA in eukaryotes. In yeast, this polymerase subunit is associated with the polymerase under suboptimal growth conditions and may have a stress protective role. A sequence for a ribosomal pseudogene is contained within the 3 untranslated region of the transcript from this gene. -
Synonyms
POLR2D; polymerase (RNA) II (DNA directed) polypeptide D; DNA-directed RNA polymerase II subunit RPB4; RBP4; RNA polymerase II subunit hsRBP4; DNA-directed RNA polymerase II 16 kDa polypeptide; DNA-directed RNA polymerase II subunit D; HSRBP4; polymerase RNA II DNA directed polypeptide D; RNA polymerase II subunit B4; RNA polymerase II subunit D; OTTHUMP00000162266; OTTHUMP00000203872; OTTHUMP00000205986; RNA polymerase II 16 kDa subunit; DNA-directed RNA p; RPB16; HSRPB4;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Mouse
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
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Human | POLR2D-15909H | Recombinant Human POLR2D, His-tagged | E.coli | His | 1-142aa | |
Human | POLR2D-1842H | Recombinant Human POLR2D, His-tagged | E.coli | His | 1-142aa | |
Human | POLR2D-3035HCL | Recombinant Human POLR2D 293 Cell Lysate | HEK293 | N/A | ||
Mouse | POLR2D-13094M | Recombinant Mouse POLR2D Protein | Mammalian Cell | His | ||
Mouse | POLR2D-6922M-B | Recombinant Mouse POLR2D Protein Pre-coupled Magnetic Beads | HEK293 | |||
Mouse | Polr2d-4996M | Recombinant Mouse Polr2d Protein, Myc/DDK-tagged | HEK293T | Myc/DDK | ||
Mouse | POLR2D-6922M | Recombinant Mouse POLR2D Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | POLR2D-3515R | Recombinant Rhesus monkey POLR2D Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | POLR2D-3333R | Recombinant Rhesus Macaque POLR2D Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | POLR2D-3333R-B | Recombinant Rhesus Macaque POLR2D Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | POLR2D-466Z | Recombinant Zebrafish POLR2D | Mammalian Cell | His | ||
Chicken | POLR2D-4813C | Recombinant Chicken POLR2D | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- POLR2D Related Articles
POLR2D involved in several pathways and played different roles in them. We selected most pathways POLR2D participated on our site, such as Purine metabolism, Pyrimidine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR2D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
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Purine metabolism | IMPDH2;ENTPD6;NT5C1B-RDH14;NUDT9;NT5C3L;POLR2L;PDE4A;CANT1A;POLA2 |
Pyrimidine metabolism | RRM2;POLE3;ZNRD1;POLA2;POLD1;POLR1B;NT5C1B-RDH14;TRR1;POLR2A |
Metabolic pathways | DGKD;PNLIPRP2;LSM1;ybaS;ATP6V1G3;NDUFA8;SCP2A;NDUFB6;PRDX6 |
RNA polymerase | POLR2J3;POLR2L;ZNRD1;POLR2K;POLR3GLB;POLR2J2;POLR2H;POLR2GL;POLR2A |
Huntingtons disease | DNAI2;POLR2J3;SLC25A5;NDUFA10;DNALC1;TRP53;GRM5;RCOR1;SLC25A31 |
Epstein-Barr virus infection | IL10RA;IKBKG;PLCG2;PIK3CB;IRF3;RB1;POLR2A;TNFAIP3;POLR2K |
POLR2D has several biochemical functions, for example, DNA-directed RNA polymerase activity, nucleotide binding, contributes_to single-stranded DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR2D itself. We selected most functions POLR2D had, and list some proteins which have the same functions with POLR2D. You can find most of the proteins on our site.
Function | Related Protein |
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DNA-directed RNA polymerase activity | MED20;POLR2J;POLR2E;POLR3K;POLR2B;POLR2EB;POLR2I;PRIM2;CD3EAP |
nucleotide binding | GLULA;MSI2B;ABCC5;SCAF8;CIRBP;TUBA4L;HNRPL;ATP2B2;RAB5AA |
contributes_to single-stranded DNA binding | PMS2;IGJ;MSH3;IGHM;MLH1;MSH2;POLR2D |
contributes_to single-stranded RNA binding | |
translation initiation factor binding | LIN28A;EIF3BA;ZFP259;EIF2B4;ZNF259;EIF3F;EIF2B3;POLR2G;POLR2D |
POLR2D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR2D here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR2D.
MED19; MED26; POLR2L; RBBP6; ssdna_dc; SUPT5H; LIMK1; POLR2G; CTR9; Med28; MED10; Rprd1b; MED9; MED29
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