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POLR3D

Official Full Name

polymerase (RNA) III (DNA directed) polypeptide D, 44kDa
Overview

This gene complements a temperature-sensitive mutant isolated from the BHK-21 Syrian hamster cell line. It leads to a block in progression through the G1 phase of the cell cycle at nonpermissive temperatures.
Synonyms

POLR3D; polymerase (RNA) III (DNA directed) polypeptide D, 44kDa; BN51 (BHK21) temperature sensitivity complementing , BN51T; DNA-directed RNA polymerase III subunit RPC4; RPC4; TSBN51; BN51T; DNA directed RNA polymerase III subunit D; RPC53; AI326118; AW489084; BN51 (BHK21) temperature sensitivity complementing; DNA directed RNA polymerase III 47 kDa polypeptide; Polymerase (RNA) III (DNA directed) polypeptide D; Protein BN51; RNA polymerase III subunit C4; Temperature sensitive complementation cell cycle specific tsBN51; RPC53 homolog; RNA polymerase III 47 kDa subunit; DNA-directed RNA polymerase III subunit D; DNA-directed RNA polymerase III 47 kDa polypeptide; temperature sensitive complementation, cell cycle specific, tsBN51;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Zebrafish

Source

E.coli
HEK293
HEK293T
Mammalian Cell
Wheat Germ

Tag

His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	POLR3D-30686TH	Recombinant Human POLR3D	Wheat Germ	N/A	100 amino acids	Inquiry
Human	POLR3D-1850H	Recombinant Human POLR3D, His-tagged	E.coli	His	45-398aa	$319 / 25ug
Human	POLR3D-3025HCL	Recombinant Human POLR3D 293 Cell Lysate	HEK293	N/A		Inquiry
Mouse	POLR3D-13107M	Recombinant Mouse POLR3D Protein	Mammalian Cell	His		Inquiry
Mouse	Polr3d-5005M	Recombinant Mouse Polr3d Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	POLR3D-6930M-B	Recombinant Mouse POLR3D Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	POLR3D-6930M	Recombinant Mouse POLR3D Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	POLR3D-10619Z	Recombinant Zebrafish POLR3D	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

POLR3D involved in several pathways and played different roles in them. We selected most pathways POLR3D participated on our site, such as Purine metabolism, Pyrimidine metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with POLR3D were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Purine metabolism	GMPR2;PDE3B;ENPP1;POLR1B;POLR3GL;POLR3A;PRIM1;GUK1A;PRUNE
Pyrimidine metabolism	POLR1E;PNP;POLR2C;POLR1B;NT5C3L;DPYS;UPB1;POLD1;ENTPD8
Metabolic pathways	NDUFS8;ALG6;NDUFA12;PTDSS1A;GCSHA;PIGK;NDUFA8;ACAA1;B4GALNT1
RNA polymerase	POLR3B;POLR1C;POLR2D;POLR2L;POLR2H;POLR2G;POLR1A;TWISTNB;POLR1E
Cytosolic DNA-sensing pathway	IFNA8;POLR1C;DDX58;CASPA;POLR3A;POLR2EB;TMEM173;POLR3E;POLR3F
Epstein-Barr virus infection	BCL2;CDK1;MAPK10;TRAF1;POLR2C;RB1;HLA-DPB1;CCNA2;ENTPD8

POLR3D has several biochemical functions, for example, DNA binding, contributes_to RNA polymerase III activity, chromatin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POLR3D itself. We selected most functions POLR3D had, and list some proteins which have the same functions with POLR3D. You can find most of the proteins on our site.

Function	Related Protein
DNA binding	ZFP787;ZNF426;ZBTB25;HOXD11A;ALS2CR8;SETBP1;DNASE1L2;ARNTL2;RAD52
contributes_to RNA polymerase III activity	POLR3H;POLR2EB;POLR3GL;POLR3E;POLR3G;POLR2E;POLR3GLA;POLR1D;POLR3F
chromatin binding	BRD2;CIC;NKX2-5;WHSC1;RELB;SMAD2;HMG20B;OVOL2;COQ7

POLR3D has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POLR3D here. Most of them are supplied by our site. Hope this information will be useful for your research of POLR3D.

SMAD2; TAB1; MAPK11; ssrna_ag; Ruvbl1; POLR2F; RNF169; CDC5L; POLR3E