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POMT2

  • Official Full Name

    protein-O-mannosyltransferase 2

  • Overview

    The protein encoded by this gene is an O-mannosyltransferase that requires interaction with the product of the POMT1 gene for enzymatic function. The encoded protein is found in the membrane of the endoplasmic reticulum. Defects in this gene are a cause of Walker-Warburg syndrome (WWS).
  • Synonyms

    POMT2; protein-O-mannosyltransferase 2; protein O-mannosyl-transferase 2; A830009D15Rik; AW046274; DKFZp686G10254; Dolichyl phosphate mannose protein mannosyltransferase 2; FLJ22309; POMT 2; Protein O mannosyltransferase 2; Protein O mannosyltransferase; Putative protein O mannosyltransferase; rCG_20643; dolichyl-phosphate-mannose--protein mannosyltransferase 2; MDDGA2; MDDGB2; MDDGC2;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human POMT2-1857H Recombinant Human POMT2, GST-tagged E.coli GST 307-602aa
Human POMT2-3016HCL Recombinant Human POMT2 293 Cell Lysate HEK293 N/A
Mouse POMT2-13121M Recombinant Mouse POMT2 Protein Mammalian Cell His
Mouse POMT2-6939M Recombinant Mouse POMT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse POMT2-6939M-B Recombinant Mouse POMT2 Protein Pre-coupled Magnetic Beads HEK293
Rhesus Macaque POMT2-3525R Recombinant Rhesus monkey POMT2 Protein, His-tagged Mammalian Cell His
Rhesus Macaque POMT2-3343R Recombinant Rhesus Macaque POMT2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque POMT2-3343R-B Recombinant Rhesus Macaque POMT2 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish POMT2-4102Z Recombinant Zebrafish POMT2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • POMT2 Related Articles

POMT2 involved in several pathways and played different roles in them. We selected most pathways POMT2 participated on our site, such as Other types of O-glycan biosynthesis, which may be useful for your reference. Also, other proteins which involved in the same pathway with POMT2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Other types of O-glycan biosynthesisB3GALTLA;B4GALT1;C3orf64;POMGNT1;ST6GAL2A;B3GALTL;ST6GAL2;FUT9A;MGAT5B

POMT2 has several biochemical functions, for example, contributes_to dolichyl-phosphate-mannose-protein mannosyltransferase activity, metal ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by POMT2 itself. We selected most functions POMT2 had, and list some proteins which have the same functions with POMT2. You can find most of the proteins on our site.

Function Related Protein
contributes_to dolichyl-phosphate-mannose-protein mannosyltransferase activityPOMT1;POMT2;SDF2L1
metal ion bindingNME7;CYP2K18;PCGF5A;EGR1;ZBTB2A;ZNF114;EIF2S2;TATDN3;CBFA2T2

POMT2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with POMT2 here. Most of them are supplied by our site. Hope this information will be useful for your research of POMT2.

Lommel, M; Winterhalter, PR; et al. Protein O-mannosylation is crucial for E-cadherin-mediated cell adhesion. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 110:21024-21029(2013).
Zhang, P; Hu, HY; et al. Differential glycosylation of alpha-dystroglycan and proteins other than alpha-dystroglycan by like-glycosyltransferase. GLYCOBIOLOGY 22:235-247(2012).
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