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PPA2

  • Official Full Name

    pyrophosphatase (inorganic) 2

  • Overview

    The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
  • Synonyms

    PPA2; pyrophosphatase (inorganic) 2; inorganic pyrophosphatase 2, mitochondrial; FLJ20459; HSPC124; PPase2; Pyrophosphatase SID6 306; PPase 2; OTTHUMP00000158985; OTTHUMP00000158986; OTTHUMP00000218513; OTTHUMP00000218514; pyrophosphatase SID6-306; pyrophosphate phospho-hydrolase 2; SID6-306;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Yeast
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PPA2-242H Recombinant Human PPA2 Protein, His-tagged E.coli His
Human PPA2-2994HCL Recombinant Human PPA2 293 Cell Lysate HEK293 N/A
Mouse PPA2-13153M Recombinant Mouse PPA2 Protein Mammalian Cell His
Mouse PPA2-6962M Recombinant Mouse PPA2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse Ppa2-5028M Recombinant Mouse Ppa2 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Mouse PPA2-6962M-B Recombinant Mouse PPA2 Protein Pre-coupled Magnetic Beads HEK293
Yeast ppa2-1868Y Recombinant Yeast ppa2, GST-tagged E.coli GST 123-322
Zebrafish PPA2-11689Z Recombinant Zebrafish PPA2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PPA2 Related Articles

PPA2 involved in several pathways and played different roles in them. We selected most pathways PPA2 participated on our site, such as Oxidative phosphorylation, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Oxidative phosphorylationATP5B;ATP5J2;NDUFA4L;NDUFA4L2;ATP6V0A2;ATP6V1F;NDUFA8;UQCRC2B;ATP5H

PPA2 has several biochemical functions, for example, inorganic diphosphatase activity, magnesium ion binding, protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPA2 itself. We selected most functions PPA2 had, and list some proteins which have the same functions with PPA2. You can find most of the proteins on our site.

Function Related Protein
inorganic diphosphatase activityPPA1A;PRUNE;PPA1;PPA1B;LHPP;PPA2
magnesium ion bindingLATS1;DYRK2;STK36;DUT;ICK;ENO1B;NUDT5;GEM;TSSK3
protein serine/threonine phosphatase activityPPP3CB;MTMR6;PTEN;PPM1DB;PPP1R15B;PPP5C;PPP1CC;PPEF2;CDC14B

PPA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PPA2.

HTT; 15-deoxy-delta(12,14; ZWINT; MYC; COMT; SIRT4

Gomez-Garcia, MR; Serrano, A; et al. Expression studies of two paralogous ppa genes encoding distinct Family I pyrophosphatases in marine unicellular cyanobacteria reveal inactivation of the typical cyanobacterial gene. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 295:890-897(2002).
Rojas-Beltran, JA; Dubois, F; et al. Identification of cystosolic Mg2+-dependent soluble inorganic pyrophosphatases in potato and phylogenetic analysis. PLANT MOLECULAR BIOLOGY 39:449-461(1999).
  • Q&As
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