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PPP2R5A

  • Official Full Name

    protein phosphatase 2, regulatory subunit B, alpha

  • Overview

    The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B56 subfamily. Alternative transcript variants encoding distinct isoforms have been found for this gene.
  • Synonyms

    PPP2R5A; protein phosphatase 2, regulatory subunit B, alpha; protein phosphatase 2, regulatory subunit B (B56), alpha isoform , protein phosphatase 2, regulatory subunit B, alpha isoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit alpha isoform; B56A; PR61A; 2A5A_HUMAN; MGC131915; PP2A B Subunit B Alpha Isoform; PP2A B Subunit B56 Alpha Isoform; PP2A B subunit isoform B-alpha; PP2A B subunit isoform B56-alpha; PP2A B subunit isoform PR61-alpha; PP2A B subunit isoform R5-alpha; PP2A B Subunit PR61 Alpha Isoform; PP2A B Subunit R5 Alpha Isoform; PR61alpha; Protein phosphatase 2 regulatory subunit B (B56) alpha isoform; Serine/Threonine Protein Phosphatase 2A 56kDa Regulatory Subunit Alpha Isoform; OTTHUMP00000034891; PP2A, B subunit, B alpha isoform; PP2A, B subunit, R5 alpha isoform; PP2A, B subunit, B56 alpha isoform; PP2A, B subunit, PR61 alpha isoform; protein phosphatase 2, regulatory subunit B, alpha isoform; protein phosphatase 2, regulatory subunit B (B56), alpha isoform; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, alpha isoform;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Human
  • Mouse
  • Rhesus Macaque
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • GST
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PPP2R5A-31104TH Recombinant Human PPP2R5A Wheat Germ N/A 486 amino acids
Human PPP2R5A-1919H Recombinant Human PPP2R5A, GST-tagged E.coli GST C-term-299aa
Human PPP2R5A-1404HCL Recombinant Human PPP2R5A cell lysate N/A
Human PPP2R5A-394HF Recombinant Full Length Human PPP2R5A Protein In Vitro Cell Free System 486 amino acids
Mouse PPP2R5A-13261M Recombinant Mouse PPP2R5A Protein Mammalian Cell His
Mouse PPP2R5A-7038M-B Recombinant Mouse PPP2R5A Protein Pre-coupled Magnetic Beads HEK293
Mouse PPP2R5A-7038M Recombinant Mouse PPP2R5A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PPP2R5A-3574R Recombinant Rhesus monkey PPP2R5A Protein, His-tagged Mammalian Cell His
Rhesus Macaque PPP2R5A-3392R Recombinant Rhesus Macaque PPP2R5A Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PPP2R5A-3392R-B Recombinant Rhesus Macaque PPP2R5A Protein Pre-coupled Magnetic Beads HEK293
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PPP2R5A involved in several pathways and played different roles in them. We selected most pathways PPP2R5A participated on our site, such as mRNA surveillance pathway, Sphingolipid signaling pathway, Oocyte meiosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP2R5A were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
mRNA surveillance pathwayFIP1L1B;PPP2R5EB;PABPC1;FIP1L1;RNMT;PPP2R2C;WDR82;ETF1A;MSI2A
Sphingolipid signaling pathwayFYN;PIK3CA;PPP2CA;SGMS2;TRADD;PTEN;PRKCA;DEGS2;TRP53
Oocyte meiosisPPP2CB;PTTG1;PPP3R2;CDC20;CALM3;CALM4;CAMK2G;IGF1RB;ANAPC7
PIK-Akt signaling pathwayGNG4;FGF4;GRB2;ANGPT2;TCL1B;Fgf15;NGF;CREB3L2;RPS6KB1
AMPK signaling pathwayRHEB;CAMKK1;CCNA2;ELAVL1;PPP2R1B;GYS2;PPP2R5E;PPP2R5D;TSC2
Adrenergic signaling in cardiomyocytesADRA1BB;TNNT2A;ADRB2B;PRKACBB;RYR2;ATP1B1B;CACNG7A;ATF4B1;ATP1A1
Dopaminergic synapseTH;DDC;DRD1;GRIA2;PRKACB;DRD4;GNB1;PLCB2;GNAO1

PPP2R5A has several biochemical functions, for example, kinase binding, protein binding, protein phosphatase type 2A regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP2R5A itself. We selected most functions PPP2R5A had, and list some proteins which have the same functions with PPP2R5A. You can find most of the proteins on our site.

Function Related Protein
kinase bindingWWC2;SRC;C2orf44;CDC37;PRPSAP1;SNAI1;CEBPA;HPCA;JAKMIP2
protein bindingDTNA;TJP1;RHOXF2;POP4;PAEP;F12;ZNF259;ITGA4;GGA1
protein phosphatase type 2A regulator activityPPP2R5EB;ENSA;EIF2AK2;IGBP1;PPP2R5EA;PPP2R5A;PPP2R5C;PPP2R2BB;PPME1

PPP2R5A has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP2R5A here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP2R5A.

PPP2CA; PPP2R1A; PPP2R1B; Ppp2r1a; Sgol2; SGOL1; CHEK2

  • Q&As
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Reviews
08/13/2020

    Incorporating protein reagents reduces operational steps in experiments, thereby increasing efficiency.

    04/22/2019

      Protein reagents yield consistent experimental results and reliable data due to their stable quality.

      04/10/2016

        Manufacturers of protein reagents adhere to strict quality management practices, ensuring reliable product quality.

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