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PPP2R5B

Official Full Name

protein phosphatase 2, regulatory subunit B, beta
Overview

The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B56 subfamily.
Synonyms

PPP2R5B; protein phosphatase 2, regulatory subunit B, beta; protein phosphatase 2, regulatory subunit B (B56), beta isoform , protein phosphatase 2, regulatory subunit B, beta isoform; serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform; B56B; FLJ35411; PP2A; B subunit; B beta isoform; B56 beta isoform; PR61 beta isoform; R5 beta isoform; PR61B; serine/threonine protein phosphatase 2A; 56 kDa regulatory subunit; beta isoform; PP2A B subunit isoform B-beta; PP2A B subunit isoform R5-beta; PP2A B subunit isoform B56-beta; PP2A B subunit isoform PR61-beta; protein phosphatase 2, regulatory subunit B, beta isoform; serine/threonine protein phosphatase 2A, 56 kDa regulatory subunit, beta isoform;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PPP2R5B-2918HCL	Recombinant Human PPP2R5B 293 Cell Lysate	HEK293	N/A		Inquiry
Human	PPP2R5B-1004H	Recombinant Human PPP2R5B Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	PPP2R5B-3704H	Recombinant Human PPP2R5B protein, GST-tagged	E.coli	GST	51-106 aa	$319 / 25ug
Mouse	Ppp2r5b-5079M	Recombinant Mouse Ppp2r5b Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry

Involved Pathway
Protein Function
Interacting Protein
PPP2R5B Related Articles

PPP2R5B involved in several pathways and played different roles in them. We selected most pathways PPP2R5B participated on our site, such as mRNA surveillance pathway, Sphingolipid signaling pathway, Oocyte meiosis, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP2R5B were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
mRNA surveillance pathway	PPP1CA;PPP2R2A;PELO;PPP1CBL;MAGOHB;MSI2;CPSF5;CASC3;WDR33
Sphingolipid signaling pathway	TNF;MAPK10;ASAH2;PPP2R5D;RELA;PPP2R5A;AKT2;PRKCB;RHOA
Oocyte meiosis	CPEB4;CPEB1B;PPP3CC;BUB1;PRKACAB;CDC27;CPEB2;IGF1R;SGOL1
PIK-Akt signaling pathway	PPP2R2A;IL7R;TNN;ITGA2;Fgf15;ITGA1;IL2RG;NGFR;PRLR
AMPK signaling pathway	PFKM;CFTR;CAB39;RAB10;CREB1;RPS6KB2;PPP2R5D;ADIPOR2;PPP2R5B
Adrenergic signaling in cardiomyocytes	CACNG7A;PIK3R1;MAPK1;PLCB3;CACNA2D2;CACNA2D3;TPMA;PRKACBB;CACNG6A
Dopaminergic synapse	KCNJ6;ITPR3;PPP2CA;PPP2R5A;PLCB3;CALM2;PPP2R5B;KCNJ3;CAMK2B

PPP2R5B has several biochemical functions, for example, protein binding, protein phosphatase type 2A regulator activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP2R5B itself. We selected most functions PPP2R5B had, and list some proteins which have the same functions with PPP2R5B. You can find most of the proteins on our site.

Function	Related Protein
protein binding	TACR2;EEA1;KCNG3;HACE1;SSX3;DNAJC15;SEC23A;NUDT22;RCC2
protein phosphatase type 2A regulator activity	IGBP1;PPP2R1A;PPP2R5A;PPP2R5EB;PPME1;pab1;PPP2R1B;PPP2R5E;ENSAA

PPP2R5B has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP2R5B here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP2R5B.

PPP2CA; IER3; CHEK2; Ppp2ca; arcB; DZIP1; PPP2R1A; KSR1; ARHGEF2

Yang, HX; Jin, GL; et al. Screening and identification of proteins interacting with nucleostemin. WORLD JOURNAL OF GASTROENTEROLOGY 11:4812-4814(2005).

Fleming, I; Busse, R; et al. Tyrosine phosphorylation and bradykinin-induced signaling in endothelial cells. AMERICAN JOURNAL OF CARDIOLOGY 80:A102-A109(1997).