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PPP3CB

Official Full Name

protein phosphatase 3, catalytic subunit, beta isozyme
Overview

Serine/threonine-protein phosphatase 2B catalytic subunit beta isoform is an enzyme that in humans is encoded by the PPP3CB gene.
Synonyms

PPP3CB; protein phosphatase 3, catalytic subunit, beta isozyme; CALNB, protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform , protein phosphatase 3 (formerly 2B), catalytic subunit, beta isoform (calcineurin A beta); serine/threonine-pro;

Type

Recombinant Proteins
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
GST
N

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PPP3CB-3813H	Recombinant Human PPP3CB protein, His-tagged	E.coli	His	1-525 aa	$319 / 25ug
Human	PPP3CB-1973H	Recombinant Human PPP3CB Protein, His&GST-tagged	E.coli	N-His&GST	Thr360-Gln524	Inquiry
Mouse	PPP3CB-13267M	Recombinant Mouse PPP3CB Protein	Mammalian Cell	His		Inquiry
Mouse	PPP3CB-7041M-B	Recombinant Mouse PPP3CB Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Mouse	PPP3Cb-1239M	Recombinant Mouse PPP3Cb protein, His-tagged	E.coli	His/GST	Thr360~Gln525	Inquiry
Mouse	PPP3CB-7041M	Recombinant Mouse PPP3CB Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	PPP3CB-4640R	Recombinant Rat PPP3CB Protein	Mammalian Cell	His		Inquiry
Rat	PPP3CB-4299R	Recombinant Rat PPP3CB Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Rat	PPP3CB-4299R-B	Recombinant Rat PPP3CB Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Zebrafish	PPP3CB-2579Z	Recombinant Zebrafish PPP3CB	Mammalian Cell	His		Inquiry
Chicken	PPP3CB-2226C	Recombinant Chicken PPP3CB	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein
PPP3CB Related Articles

PPP3CB involved in several pathways and played different roles in them. We selected most pathways PPP3CB participated on our site, such as MAPK signaling pathway, Calcium signaling pathway, cGMP-PKG signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP3CB were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
MAPK signaling pathway	MAPK12B;PRKCBA;CACNG1A;MRAS;IL1B;FGF13B;MAP4K1;PPM1A;FGF5
Calcium signaling pathway	EGFRA;PRKCB;CACNA1G;TMEM8C;DRD5;TACR1;TACR1A;PPP3CCA;PLCB2
cGMP-PKG signaling pathway	CALML3;SLC25A5;NFATC1;PRKCE;NFATC2;VASP;PDE2A;GNAI1;SLC25A31
Oocyte meiosis	SGOL1;FBXW11A;PPP3CA;FBXW11B;MAP2K1;ADCY1A;FBXW11;YWHAE1;ANAPC2
Apoptosis	CAPN1B;STK24A;PLEC;PIK3R2;PRKACAB;IRF2A;CASP6L2;PTBP3;TRAF2
Wnt signaling pathway	FZD2;WNT3A;RAC2;DVL3A;SKP1;PPP3CCA;CAMK2G;CAMK2D;WNT11B
Axon guidance	RAC2;CLASP1;DPYSL4;CFL2;PLXNA3;HRAS;DNM1;SRGAP3;SEMA3A
VEGF signaling pathway	MAPKAPK2A;PIK3R2;CDC42L2;MAPK3;MAPK11;HRASB;PTGS2B;RAC3B;MAPK14A
Osteoclast differentiation	PIK3R1;TRAF6;IKBKB;PIK3CB;TAB2;LILRA5;SIRPG;MAPK8;FCGR3
Natural killer cell mediated cytotoxicity	ZAP70;PIK3CB;IFNAR2;IFNA1;Ifna11;MAPK1;SH2D1B;FAS;MAP2K1
T cell receptor signaling pathway	IL5;HRAS;VAV2;CD3D;TNF;LCP2;MAPK11;GRAP2;CABIN1
B cell receptor signaling pathway	ARPC4;PLCG2;BCL10;VAV3;CD22;SOS1;FCGR2B;CDK6;RAP2A
Long-term potentiation	PPP3CC;RAF1;PLCB2;CALM2;CAMK2A;GRIA2;ATF4;GRIN1;GRIA1
Glutamatergic synapse	GNG5;GNG4;PRKCB;DLGAP1;GNAI2;GNB4;SLC1A7;GNG2;GNAI3
Dopaminergic synapse	PPP1CB;AKT2;PPP2R5D;KIF5B;GRIA3;GNAS;PPP2R2B;MAPK8;DRD4
Oxytocin signaling pathway	PIK3CG;MYL9;RGS2;PRKAB1;PLA2G4D;MYLK;CALM1;NRAS;PIK3CB
Renin secretion	REN;GNAI1;LOC100328615;PDE1C;AGTR1B;GUCY1B3;REN2;CALM2;ACE
Alzheimers disease	EIF2AK3;ATP2A3;COX5B;NDUFB4;COX7C;AKR1C1;CALML5;NDUFA1;COX6A1
Amyotrophic lateral sclerosis (ALS)	BCL2L1;GRIN2D;GRIN2C;PPP3R2;BID;GRIN2A;Casp3;NOS1;NEFM
Tuberculosis	HSPD1;IFNB1;Itgam&Itgb2;CD209;IFNA8;ATP6V0D1;HLA-DOB;HLA-DRB5;NFYC
HTLV-I infection	PIK3CD;PIK3CA;WNT16;IL2RA;Pdgfa&Pdgfb;PRKACG;WNT11;WNT5A;IKBKB

PPP3CB has several biochemical functions, for example, calcium ion binding, calcium-dependent protein serine/threonine phosphatase activity, calmodulin binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP3CB itself. We selected most functions PPP3CB had, and list some proteins which have the same functions with PPP3CB. You can find most of the proteins on our site.

Function	Related Protein
calcium ion binding	SLC24A4A;KCNIP4;CIB1;CALR;PCDHGC5;FBN2;PCDHA6;CRELD2;CDH19
calcium-dependent protein serine/threonine phosphatase activity	NETO2;CAMK2G;PPP3R1;PPP3CB
calmodulin binding	SLC9A1;MARCKSA;ASPM;KCNH1;CAMKK2;EDF1;MYH7;SPA17;PDE1B
calmodulin-dependent protein phosphatase activity	PPM1F;PPP3CB;PPM1A;PPP3CA
drug binding	CHKA;SFRP1;HMGCS1;GLRB;PDE2A;PDE10A;CHRNB4;DHFR;GRIK1
enzyme binding	DDX5;ZNF346;UGT1A9;PRMT1;HMOX1;NKX2-1;PTPN1;TSPAN14;CYP3A4
hydrolase activity	CES1D;PPM1H;NCEH1B;CPSF3L;FHIT;CASP3A;Chil3;PLAUA;MCM6L
metal ion binding	CA15C;RBM4B;NRP1;PRKAA2;RRM2B;GALNT14;AGBL4;KLF11B;ZNF7
phosphoprotein phosphatase activity	DUSP22B;PPM1LB;PTPN23A;PPP1CBL;PTPN2B;PTPRQ;PPP4CB;PTPRJA;PPM1DA
protein binding	COL6A5;ADPRH;NLK;TSEN54;PACSIN3;RASSF9;MSMB;PLEKHH2;SCG5
protein dimerization activity	DAO1;ID4;OLIG3;BHLHE41;MXD3;ZBED1;HES2.1;MSGN1;HER3
protein heterodimerization activity	ROPN1B;ZHX1;ARNT;HIST1H2BI;PANX1;IRAK2;VAPB;SYT14;TPD52L2
protein phosphatase 2B binding	AKAP5;PPP3CB;AKAP1;ATP2B4;MYOZ2;SOD1;BAD;SLC9A1
protein serine/threonine phosphatase activity	PPM1LA;PPM1AB;PTEN;DUSP23A;PPP1R3C;PPP5C;CTDNEP1A;PPM1BB;PPM1F

PPP3CB has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP3CB here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP3CB.

Akap5; NFATC1; Akap6; Ppp3r1; Hmga2; Ywhae; Dlg4; Map3k5

Vasu, S; McClenaghan, NH; et al. Cellular responses of novel human pancreatic beta-cell line, 1.1B4 to hyperglycemia. ISLETS 5:170-177(2013).

Polovkova, OG; Makeeva, OA; et al. Expression Profiles of Calcineurin Pathway Genes in Myocardium in Relation to Ischemic Heart Remodeling in Humans. MOLECULAR BIOLOGY 47:382-388(2013).