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PPP6C

  • Official Full Name

    protein phosphatase 6, catalytic subunit

  • Overview

    This gene encodes the catalytic subunit of protein phosphatase, a component of a signaling pathway regulating cell cycle progression.
  • Synonyms

    PPP6C; protein phosphatase 6, catalytic subunit; serine/threonine-protein phosphatase 6 catalytic subunit; PP6; serine/threonine protein phosphatase catalytic subunit; PP6C; FLJ92648; MGC12249;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • In Vitro Cell Free System
  • Mammalian Cell
  • Wheat Germ
  • His
  • His (Fc)
  • Avi
  • N/A
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PPP6C-29541TH Recombinant Human PPP6C Wheat Germ N/A 305 amino acids
Human PPP6C-1928H Recombinant Human PPP6C, His-tagged E.coli His 1-305aa
Human PPP6C-1407HCL Recombinant Human PPP6C cell lysate N/A
Human PPP6C-400HF Recombinant Full Length Human PPP6C Protein In Vitro Cell Free System 305 amino acids
Mouse PPP6C-13276M Recombinant Mouse PPP6C Protein Mammalian Cell His
Mouse PPP6C-7046M Recombinant Mouse PPP6C Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PPP6C-7046M-B Recombinant Mouse PPP6C Protein Pre-coupled Magnetic Beads HEK293
Rat PPP6C-4646R Recombinant Rat PPP6C Protein Mammalian Cell His
Rat PPP6C-4305R Recombinant Rat PPP6C Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PPP6C-4305R-B Recombinant Rat PPP6C Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PPP6C-11238Z Recombinant Zebrafish PPP6C Mammalian Cell His
Chicken PPP6C-3597C Recombinant Chicken PPP6C Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PPP6C Related Articles

PPP6C involved in several pathways and played different roles in them. We selected most pathways PPP6C participated on our site, such as Asparagine N-linked glycosylation, COPII (Coat Protein 2) Mediated Vesicle Transport, ER to Golgi Anterograde Transport, which may be useful for your reference. Also, other proteins which involved in the same pathway with PPP6C were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Asparagine N-linked glycosylationPPP6R1;TRAPPC5;ST3GAL3A;SERPINA1L;GNE;TRAPPC6B;MLEC;MGAT4B;CTSZ
COPII (Coat Protein 2) Mediated Vesicle TransportSEC22A;YKT6;TRAPPC3;TRAPPC6A;TRAPPC6B;SEC24A;SERPINA1L;TRAPPC2L;NAPAA
ER to Golgi Anterograde TransportCNIH3;TRAPPC6BL;NAPAA;CTSC;SERPINA1L;SEC23IP;TRAPPC5;TRAPPC2;TRAPPC6A
Membrane TraffickingGJB7;AP1S3A;SEC22A;CTAGE5;GJA8;HIP1R;CNO;CNIH;TRAPPC6B
Metabolism of proteinsSFTPC;PFDN5;CNIH2;SUMF2;SLC30A5;MUC5AC;PCSK1;EEF1A1;CCDC59
Post-translational protein modificationANKRD28;SENP1;MCFD2;ADAMTSL5;PHC1;SPON2;ARSF;TRAPPC2L;EID3
Transport to the Golgi and subsequent modificationTRAPPC5;TRAPPC1;BET1;ANKRD28;SEC23IP;TRAPPC3;TRAPPC6B;TRAPPC6A;CNIH
Vesicle-mediated transportTBC1D8B;PPP6R3;HIP1R;CLVS2;PICALMB;COPZ1;SNF8;COPE;MIA3

PPP6C has several biochemical functions, for example, metal ion binding, protein binding, protein serine/threonine phosphatase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PPP6C itself. We selected most functions PPP6C had, and list some proteins which have the same functions with PPP6C. You can find most of the proteins on our site.

Function Related Protein
metal ion bindingPRKD3;TNNI3;STAC;RNASEH2A;KLF18;ADAL;BRCC3;ZNF395;JADE3
protein bindingMCCC2;ADAMTS3;PPAP2B;ADAMTS4;POLR2A;ZCCHC12;TUBA3E;BAZ1A;NCK1
protein serine/threonine phosphatase activityPPM1H;PPP6C;PTEN;PPM1AA;DULLARD;PPP3CA;PPM1G;PPM1DB;CDC14B

PPP6C has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PPP6C here. Most of them are supplied by our site. Hope this information will be useful for your research of PPP6C.

IGBP1; PPP6R1

Liu, Y; Zhang, LW; et al. DNA-PKcs Deficiency Inhibits Glioblastoma Cell-Derived Angiogenesis After Ionizing Radiation. JOURNAL OF CELLULAR PHYSIOLOGY 230:1094-1103(2015).
Crajoinas, RO; Pessoa, TD; et al. Changes in the activity and expression of protein phosphatase-1 accompany the differential regulation of NHE3 before and after the onset of hypertension in spontaneously hypertensive rats. ACTA PHYSIOLOGICA 211:395-408(2014).
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