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PRKACG

Official Full Name

protein kinase, cAMP-dependent, catalytic, gamma
Overview

Cyclic AMP-dependent protein kinase (PKA) consists of two catalytic subunits and a regulatory subunit dimer. This gene encodes the gamma form of its catalytic subunit. The gene is intronless and is thought to be a retrotransposon derived from the gene for the alpha form of the PKA catalytic subunit.
Synonyms

PRKACG; protein kinase, cAMP-dependent, catalytic, gamma; cAMP-dependent protein kinase catalytic subunit gamma; PKACg; KAPCG_HUMAN; KAPG; PKA C gamma; PKA C-gamma; Protein kinase cAMP dependent catalytic gamma; Serine (threonine) protein kinase; OTTHUMP00000021422; serine(threonine) protein kinase;

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PRKACG-1948H	Recombinant Human PRKACG, GST-tagged	E.coli	GST	1-351aa	$319 / 25ug
Human	PRKACG-30211TH	Recombinant Human PRKACG		N/A		Inquiry
Human	PRKACG-396H	Recombinant Human PRKACG, GST-tagged, Active	Sf9 Insect Cell	GST		Inquiry
Human	PRKACG-2867HCL	Recombinant Human PRKACG 293 Cell Lysate	HEK293	N/A		Inquiry
Human	PRKACG-3344HF	Active Recombinant Full Length Human PRKACG Protein, GST-tagged	Insect (sf21)	GST	1-351(end)	Inquiry

Involved Pathway
Protein Function
Interacting Protein
PRKACG Related Articles

PRKACG involved in several pathways and played different roles in them. We selected most pathways PRKACG participated on our site, such as MAPK signaling pathway, Ras signaling pathway, Calcium signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with PRKACG were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
MAPK signaling pathway	HSPA6;MAP3K1;C11orf52;FGF19;PAK2B;RPS6KA6;PRKCA;GRB2;CACNA1B
Ras signaling pathway	PRKCG;CALM4;GRIN2B;Kitl;INS1;MET;PAK3;CALM3;FGF1
Calcium signaling pathway	HRH1;CHRM5;VDAC3;PLCD3A;TACR1A;PLCB4;SLC8A4A;NOS2;PRKACB
cAMP signaling pathway	PDE4B;VAV1;ROCK1;PIK3CA;RAC3;PLD2;MAP2K1;FSHB;NPY
Chemokine signaling pathway	CCL8;GNG2;PRKCD;GNG10;PPBP;Cxcl15;GRK6;GNAI1;CX3CL1
Oocyte meiosis	YWHAB;INS;PPP1CAB;RPS6KA6;CAMK2A;CAMK2G1;SLK;ADCY1B;ANAPC7
Apoptosis	GZME;PIK3R5;DIABLO;TNFRSFA;TRP53;IL1RAP;IL1B;DFFA;PPP3R1
Adrenergic signaling in cardiomyocytes	ATP1B1A;ATP2A2;SCN1BB;PIK3R3B;CACNA2D2;GNA15.1;ADCY2B;ADCY9;SLC9A1
Vascular smooth muscle contraction	MYL6B;AGTR1A;ADCY1A;ACTG2;EDNRAA;PLCB1;PLA2G12A;PRKACBB;PRKCE
Wnt signaling pathway	CAMK2D2;DAAM1;WNT9B;WNT11;PORCN;SIAH1A;TCF7;NFATC2;CTNNBIP1
Hedgehog signaling pathway	LRP2A;PRKACBA;WNT9A;LRP2;WNT3A;GLI2B;WNT7B;IHHA;WNT9B
Gap junction	DRD2B;GUCY1A3;GNAI2A;TUBB6;GJD2;NRAS;MAP3K2;PLCB4;PRKCBB
Platelet activation	PRKACA;SRC;FGB;MYL12B;ACTB;TBXAS1;PTGS1;FGA;GNAS
Circadian entrainment	GNG3;RYR1;GNG7;PRKCG;PRKCB;PLCB4;PRKACB;MAPK3;GNB4
Long-term potentiation	GRM5;HRAS;CALML5;GRIN2D;CALM2;KRAS;PRKACG;GRIA1;PLCB2
Retrograde endocannabinoid signaling	GABRA4;PRKCA;GNG4;SLC17A8;GNGT2;GABRP;GABRB1;GNGT1;GNG2
Glutamatergic synapse	PLD2;SLC38A1;PPP3CB;GNB4;GRM7;MAPK1;GNG4;GNB1;GRIN2C
Cholinergic synapse	PIK3R5;CHRM4;GNG7;GNG8;CREB3L4;GNAI2;KCNJ3;KCNQ2;KCNJ14
Serotonergic synapse	PLA2G4F;KCND2;HTR1E;HTR4;CYP2C38;GNAI1;ALOX12B;PLCB1;ITPR1
GABAergic synapse	Adcy4;GABRR1;PRKCB;GABRG2;SLC38A1;GNAO1;GABRA3;GABRA1;GNG12
Dopaminergic synapse	CALM3;PPP2R3C;CALY;CALM2;SLC18A1;ATF6B;PPP2R5B;PPP2R1B;DDC
Olfactory transduction	PDC;OR11A1;OR2A4;OR7C1;OR2L2;OLFR470;OLFR186;OR10C1;OR2A42
Taste transduction	TAS2R42;TAS1R2;TAS2R118;TAS2R140;TAS2R40;GNG3;TAS2R38;TAS2R114;TAS2R116
Inflammatory mediator regulation of TRP channels	PLA2G4C;PLCB1;PRKCD;PIK3R1;CYP2J2;CYP4A12A;CAMK2D;MAPK9;BDKRB1
Insulin signaling pathway	GRB2B;PRKAB2;SOCS3B;MTOR;AKT2L;CALM2A;MAPK8B;PDPK1B;PRKAA2
Insulin secretion	GLP1R;GCG;RAB3A;PDX1;ATP1A3;ITPR3;SNAP25;CAMK2B;KCNN4
GnRH signaling pathway	ATF4;PRKCD;GNAQ;ADCY2B;MAPK8A;GNRH3;GRB2A;PLD1;MMP14B
Ovarian steroidogenesis	INS1;BMP15;INSR;HSD3B2;INS;AKR1C3;HSD17B1;HSD17B7;PTGS2
Progesterone-mediated oocyte maturation	CPEB4;AKT2L;PGR;CDC16;PKMYT1;ADCY2B;MAPK9;PIK3CG;CCNB1
Estrogen signaling pathway	KCNJ6;OPRM1;PLCB2;GNAO1;SHC1;SRC;PRKACB;HSPA6;CALM2
Melanogenesis	Fzd4;GNAO1A;HRASB;PRKCBA;KITLGA;WNT7B;PRKCB;LEF1;TYR
Thyroid hormone synthesis	TSHB;ATP1B1;PLCB3;CANX;GPX3;Adcy4;FXYD2;ATP1B4;CREB3L3
Thyroid hormone signaling pathway	NCOA1;PIK3CB;THRB;MAP2K1;DIO3;HIF1A;PRKACG;RHEB;PIK3R1
Oxytocin signaling pathway	CALM1;RCAN1;PLCB2;PIK3R2;MYL6;CACNA2D2;TRPM2;PRKCG;CACNG7
Regulation of lipolysis in adipocytes	AKT2;INS;INS2;IRS1;AKT1;PRKG2;PDE3B;LOC100328615;GNAI1
Renin secretion	Ren1;CLCA2;AGTR1A;CALM4;PDE1A;GUCY1A3;PTGER2;GUCY1B3;GNAQ
Aldosterone synthesis and secretion	NR4A1;PLCB2;AGTR1A;KCNK3;DDX1;STAR;PRKACA;SLC14A2;GNAS
Endocrine and other factor-regulated calcium reabsorption	ATP1B2;PRKACG;DNM3;PRKACB;KLK1B9;KL;PTH1R;KLK1B8;ATP1A1
Salivary secretion	PRKACA;MUC5B;PRKACB;PRKG1;CST2;GUCY1B3;CALML5;Adcy4;TRPV6
Gastric acid secretion	PLCB3;GAST;CAMK2A;ATP1A2;ITPR3;GNAQ;CALM2;ATP1B2;ATP4B
Bile secretion	SLC27A5;CFTR;Abcb1b;LDLR;SLCO1B2;SLC10A1;AQP4;SLC4A4;CYP3A4
Parkinsons disease	NDUFB2;NDUFA13;NDUFA5;UBB;UQCR11;SDHB;UQCRQ;SLC6A3;mt-Atp8
Prion diseases	C1QA;Hc;PRKACB;LOC100033925;C5;CASP12;HSPA1A;CCL5;MAP2K1
Cocaine addiction	ATF6B;MAOA;NFKB1;GRIN2C;CREB3L4;CREB3L1;CREB3;GRIN2A;SLC6A3
Vibrio cholerae infection	ATP6V1F;ATP6V0A1;PRKACA;ATP6V1B2;PRKACB;ATP6V1B1;ATP6V1A;ATP6V0C;TJP2
Amoebiasis	IFNG;NOS2;PIK3CG;LAMA3;SERPINB13;Itgam&Itgb2;IL10;TLR4;COL24A1
HTLV-I infection	VDAC2;WNT9A;IL2RB;HRAS;HLA-DPB1;CD3E; CD3D;HLA-DMA;MYB;RELA
Epstein-Barr virus infection	SYK;NFKB2;POLR2C;POLR2G;PSMC4;YWHAG;MAP2K4;RBPJL;POLR3E
Pathways in cancer	AXIN1;CASP9;ARNT;WNT5A;EGLN1;LAMB1;DAPK1;SFPI1;FZD6
Viral carcinogenesis	UBR4;PSMC1;GTF2H3;H2BFWT;TBPL2;PRKACA;GRB2;RBL1;SND1
Proteoglycans in cancer	PRKACB;PIK3CG;PRKCG;CTTN;WNT1;CAV2;WNT4;RPS6KB1;HIF1A
Dilated cardiomyopathy	CACNG4;ITGA4;CACNA2D2;Adcy4;CACNG2;ITGAV;DES;ITGB5;PRKACA

PRKACG has several biochemical functions, for example, ATP binding, cAMP-dependent protein kinase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PRKACG itself. We selected most functions PRKACG had, and list some proteins which have the same functions with PRKACG. You can find most of the proteins on our site.

Function	Related Protein
ATP binding	MKI67;ATP13A1;HIPK3A;DSTYK;TXK;HSP90AA1.2;OBSCN;TAE1;RRM1
cAMP-dependent protein kinase activity	PRKACA;PRKX;PRKACB;PRKAA1;AKAP13;PRKAG1;PRKACG

PRKACG has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PRKACG here. Most of them are supplied by our site. Hope this information will be useful for your research of PRKACG.

CETP; CDK17; PRKACA

Lee, JW; Chen, H; et al. Protein Kinase A-alpha Directly Phosphorylates FoxO1 in Vascular Endothelial Cells to Regulate Expression of Vascular Cellular Adhesion Molecule-1 mRNA. JOURNAL OF BIOLOGICAL CHEMISTRY 286:6423-6432(2011).

Yao, L; Fan, PD; et al. Dopamine and ethanol cause translocation of epsilon PKC associated with epsilon RACK: Cross-talk between cAMP-dependent protein kinase A and protein kinase C signaling pathways. MOLECULAR PHARMACOLOGY 73:1105-1112(2008).