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PRPF18
Official Full Name
PRP18 pre-mRNA processing factor 18 homolog (yeast)
Background
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is found to be essential for the catalytic step II in pre-mRNA splicing process. It is found in the spliceosome, and contains seven WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to the yeast splicing factor Prp18.
Synonyms
PRPF18; PRP18 pre-mRNA processing factor 18 homolog (yeast); pre-mRNA-splicing factor 18; PRP18 homolog; HPRP18 homolog; 2810441A10Rik