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PSCA

  • Official Full Name

    prostate stem cell antigen

  • Overview

    This gene encodes a glycosylphosphatidylinositol-anchored cell membrane glycoprotein. In addition to being highly expressed in the prostate it is also expressed in the bladder, placenta, colon, kidney, and stomach. This gene is up-regulated in a large proportion of prostate cancers and is also detected in cancers of the bladder and pancreas. This gene includes a polymorphism that results in an upstream start codon in some individuals; this polymorphism is thought to be associated with a risk for certain gastric and bladder cancers. Alternative splicing results in multiple transcript variants.
  • Synonyms

    PSCA; prostate stem cell antigen; PRO232;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Human
  • Mouse
  • E.coli
  • HEK293
  • Human Cells
  • Yeast
  • C
  • hFc
  • His
  • Avi
  • DDK
  • GST
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PSCA-2003H Recombinant Human PSCA protein, His-tagged E.coli His Leu22~Ser95
Human PSCA-2001H Recombinant Human PSCA, GST-tagged E.coli GST 1-100aa
Human PSCA-2002H Recombinant Human PSCA protein, His-tagged E.coli His Leu22~Leu123
Human PSCA-2791HCL Recombinant Human PSCA 293 Cell Lysate HEK293 N/A
Human PSCA-0630H Active Recombinant Human PSCA protein, His-Avi-tagged, Biotinylated HEK293 His-Avi Leu12-Ser86
Human PSCA-3378H Recombinant Human PSCA protein, GST-tagged E.coli GST 12-86aa
Human PSCA-151H Recombinant Human PSCA Protein, His-tagged Human Cells His
Human PSCA-3061H Recombinant Human PSCA Protein, DDK-tagged HEK293 DDK
Human PSCA-0631H Active Recombinant Human PSCA protein, His-tagged HEK293 His Leu12-Ser86
Human PSCA-6600H Recombinant Human PSCA Protein (Leu12-Ser86), N-His tagged E.coli N-His Leu12-Ser86
Human PSCA-3379H Recombinant Human PSCA protein, His&His-tagged E.coli His&His 13-86aa
Human PSCA-2097H Recombinant Human PSCA Protein (21-95 aa), His-tagged Yeast His 21-95 aa
Human PSCA-454H Recombinant Human PSCA Protein (Leu12-Ser86), C-hFc-tagged HEK293 C-hFc Leu12-Ser86
Human PSCA-01HP Recombinant Human PSCA Protein, C-His-tagged, PE-labeled HEK293 C-His 21-95 aa
Mouse PSCA-1495M Recombinant Mouse PSCA Protein (21-95 aa), His-tagged Yeast His 21-95 aa
Mouse PSCA-0629M Recombinant Mouse PSCA protein(Met1-Asn95), His&Avi-tagged, Biotinylated HEK293 C-His&Avi Met1-Asn95
  • PSCA Related Articles
  • PSCA Related Research Area

PSCA involved in several pathways and played different roles in them. We selected most pathways PSCA participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PSCA were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein

PSCA has several biochemical functions, for example, . Some of the functions are cooperated with other proteins, some of the functions could acted by PSCA itself. We selected most functions PSCA had, and list some proteins which have the same functions with PSCA. You can find most of the proteins on our site.

Function Related Protein

PSCA has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSCA here. Most of them are supplied by our site. Hope this information will be useful for your research of PSCA.

Tiezzi, F; Parker-Gaddis, KL; et al. A Genome-Wide Association Study for Clinical Mastitis in First Parity US Holstein Cows Using Single-Step Approach and Genomic Matrix Re-Weighting Procedure. PLOS ONE 10:-(2015).
Knowles, SM; Tavare, R; et al. Applications of ImmunoPET: Using I-124-Anti-PSCA A11 Minibody for Imaging Disease Progression and Response to Therapy in Mouse Xenograft Models of Prostate Cancer. CLINICAL CANCER RESEARCH 20:6367-6378(2014).
  • Q&As
  • Reviews

Q&As (7)

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Does PSCA have any known genetic variations? 12/18/2021

Genetic variations in PSCA have been studied, and certain polymorphisms may be associated with cancer susceptibility.

Are there therapeutic implications related to PSCA? 08/14/2020

PSCA is being explored as a potential target for therapeutic interventions in prostate cancer treatment.

In which context is PSCA commonly studied? 12/30/2018

PSCA is often studied in the context of prostate cancer, as it is overexpressed in prostate cancer cells.

What is the role of PSCA in prostate cancer? 04/25/2018

PSCA may play a role in prostate cancer progression, and its overexpression is associated with malignancy.

What does PSCA stand for? 04/11/2018

PSCA stands for Prostate Stem Cell Antigen.

Can PSCA be a potential biomarker for prostate cancer? 05/22/2016

Yes, PSCA is considered a potential biomarker for prostate cancer due to its overexpression in prostate cancer cells.

Is PSCA expressed only in the prostate? 04/05/2016

While PSCA is notably expressed in the prostate, its expression has also been reported in other tissues and organs.

Customer Reviews (3)

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Reviews
12/04/2019

    User-friendly data analysis capabilities contributed to the product's overall value for our research.

    07/27/2017

      The software and resources provided by the manufacturer greatly facilitated the extraction of meaningful insights from our data.

      02/21/2017

        The product's user-friendly features facilitated seamless collaboration among team members with different expertise levels.

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