PSMB6
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Official Full Name
proteasome (prosome, macropain) subunit, beta type, 6
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Overview
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 1i (proteasome beta 9 subunit). -
Synonyms
PSMB6; proteasome (prosome, macropain) subunit, beta type, 6; proteasome subunit beta type-6; DELTA; Y; proteasome subunit Y; macropain delta chain; proteasome delta chain; proteasome subunit delta; proteasome subunit beta 6; proteasome catalytic subunit;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Human
- Mouse
- Rat
- Rhesus Macaque
- Zebrafish
- E.coli
- HEK293
- HEK293T
- Mammalian Cell
- GST
- His
- His (Fc)
- Avi
- Myc
- DDK
- N/A
- Involved Pathway
- Protein Function
- Interacting Protein
PSMB6 involved in several pathways and played different roles in them. We selected most pathways PSMB6 participated on our site, such as Proteasome, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMB6 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Proteasome | PSMC1B;PSMB9;PSMB1;PSMC6;PSMA3;PSMC1A;PSMF1;PSMB4;PSMD2 |
PSMB6 has several biochemical functions, for example, endopeptidase activity, threonine-type endopeptidase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMB6 itself. We selected most functions PSMB6 had, and list some proteins which have the same functions with PSMB6. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| endopeptidase activity | PSMB9B;KLK1B11;PSMB9A;MMP3;MMP9;P4HB;HTRA4;TPP1;PSMA6B |
| threonine-type endopeptidase activity | PSMB10;PSMB3;PSMB4;PSMA5;PSMB9B;PSMB2;PSMB5;PSMB8;PSMA4 |
PSMB6 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMB6 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMB6.
UCHL5; PSMB7; POMP; VCAM1; env; HLA-B; MDM2; IKBKE; TRAF6; EZH2; PSMA7; Psmd14
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