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PSMD10

  • Official Full Name

    proteasome (prosome, macropain) 26S subunit, non-ATPase, 10

  • Overview

    This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.
  • Synonyms

    PSMD10; proteasome (prosome, macropain) 26S subunit, non-ATPase, 10; 26S proteasome non-ATPase regulatory subunit 10; gankyrin; p28; ankyrin repeat protein; 26S proteasome regulatory subunit p28; hepatocellular carcinoma-associated protein p28-II; p28(GAN;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Human
  • Mouse
  • Rat
  • Rhesus Macaque
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • GST
  • His
  • His (Fc)
  • Avi
  • His|T7
  • SUMO
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PSMD10-2026H Recombinant Human PSMD10, GST-tagged E.coli GST 1-226aa
Human PSMD10-6927H Recombinant Human Proteasome (prosome, macropain) 26S Subunit, Non-ATPase, 10 E.coli N/A 1-226aa
Human PSMD10-358H Recombinant Human Proteasome (prosome, macropain) 26S Subunit, Non-ATPase, 10 E.coli N/A
Human PSMD10-2755HCL Recombinant Human PSMD10 293 Cell Lysate HEK293 N/A
Human PSMD10-2756HCL Recombinant Human PSMD10 293 Cell Lysate HEK293 N/A
Human PSMD10-3383H Recombinant Human PSMD10 protein, His-SUMO-tagged E.coli His-SUMO 1-226aa
Human PSMD10-1502H Recombinant Human PSMD10 protein, His & T7-tagged E.coli His/T7 Met1~Gly226 (Accession # O75832)
Human PSMD10-1136H Recombinant Human PSMD10 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PSMD10-2742H Recombinant Human PSMD10 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PSMD10-6050H Recombinant Human PSMD10 Protein (Met1-Gly226), N-GST tagged E.coli N-GST Met1-Gly226
Human PSMD10-6051H Recombinant Human PSMD10 Protein (Met1-Gly226), N-His tagged E.coli N-His Met1-Gly226
Mouse Psmd10-5189M Recombinant Mouse Psmd10 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PSMD10-4785R Recombinant Rat PSMD10 Protein Mammalian Cell His
Rat PSMD10-4444R-B Recombinant Rat PSMD10 Protein Pre-coupled Magnetic Beads HEK293
Rat PSMD10-4444R Recombinant Rat PSMD10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PSMD10-3668R Recombinant Rhesus monkey PSMD10 Protein, His-tagged Mammalian Cell His
Rhesus Macaque PSMD10-3486R Recombinant Rhesus Macaque PSMD10 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rhesus Macaque PSMD10-3486R-B Recombinant Rhesus Macaque PSMD10 Protein Pre-coupled Magnetic Beads HEK293
Zebrafish PSMD10-11769Z Recombinant Zebrafish PSMD10 Mammalian Cell His
Chicken PSMD10-5240C Recombinant Chicken PSMD10 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PSMD10 involved in several pathways and played different roles in them. We selected most pathways PSMD10 participated on our site, such as APC/C-mediated degradation of cell cycle proteins, APC/C:Cdc20 mediated degradation of Securin, APC/C:Cdc20 mediated degradation of mitotic proteins, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMD10 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
APC/C-mediated degradation of cell cycle proteinsPSMD5;AURKB;UBE2C;ANAPC10;PSMD10;PSMD14;PSME3;CDK2;NEK2
APC/C:Cdc20 mediated degradation of SecurinPSME3;ANAPC10;UBE2C;PSMD5;PSMD14;PSMD9;PSMD10;PSMA8
APC/C:Cdc20 mediated degradation of mitotic proteinsANAPC10;PSME3;UBE2C;PSMD10;PSMA8;PSMD9;PSMD14;NEK2;PSMD5
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1AURKB;ANAPC10;PSMD14;PSME3;PSMD5;PSMD9;PSMA8;PSMD10;UBE2C
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpointPSMD10;PSME3;PSMD14;UBE2C;ANAPC10;PSMA8;PSMD9;PSMD5;NEK2
ARMS-mediated activationSPTBN2;NETO2;DUSP5;PEA15;KIDINS220B;DUSP1;FRS2B;FGF10B;HBEGF
AUF1 (hnRNP D0) binds and destabilizes mRNAHNRNPD;PSMD9;PSMA8;PSMD5;PSMD10;PSMD14;PSME3;EIF4G1
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteinsANAPC10;PSME3;PSMD5;NEK2;PSMA8;PSMD14;PSMD10;PSMD9;UBE2C

PSMD10 has several biochemical functions, for example, protein binding, transcription factor binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMD10 itself. We selected most functions PSMD10 had, and list some proteins which have the same functions with PSMD10. You can find most of the proteins on our site.

Function Related Protein
protein bindingSH3GLB2;SREK1;CARKD;NUDT12;FAM212A;NME4;ANGPTL4;WDR77;MKI67IP
transcription factor bindingTBX5;DNAJA3;TRIB2;IFI203;IFI16;CREBBP;REST;NKX2;PARP1

PSMD10 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMD10 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMD10.

PSMC4; PSMC1; PSMD7

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