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PSMD13

  • Official Full Name

    proteasome (prosome, macropain) 26S subunit, non-ATPase, 13

  • Overview

    The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway.An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described.
  • Synonyms

    PSMD13; proteasome (prosome, macropain) 26S subunit, non-ATPase, 13; 26S proteasome non-ATPase regulatory subunit 13; p40.5; Rpn9; 26S proteasome non ATPase regulatory subunit 13; 26S proteasome regulatory subunit S11; S11; 26S proteasome subunit p40.5; 26S proteasome regulatory subunit RPN9; 26S proteasome regulatory subunit p40.5; HSPC027;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Cynomolgus Monkey
  • Human
  • Mouse
  • Rat
  • Zebrafish
  • E.coli
  • HEK293
  • HEK293T
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PSMD13-212H Recombinant Human PSMD13, His-tagged E.coli His 1-376aa
Human PSMD13-2029H Recombinant Human PSMD13, His-tagged E.coli His 1-376aa
Human PSMD13-2752HCL Recombinant Human PSMD13 293 Cell Lysate HEK293 N/A
Human PSMD13-6052H Recombinant Human PSMD13 Protein (Met1-Thr378), His tagged E.coli His Met1-Thr378
Human PSMD13-1172H Recombinant Human PSMD13 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human PSMD13-6053H Recombinant Human PSMD13 Protein (Met1-Thr376), N-His tagged E.coli N-His Met1-Thr376
Mouse Psmd13-5191M Recombinant Mouse Psmd13 Protein, Myc/DDK-tagged HEK293T Myc/DDK
Rat PSMD13-4786R Recombinant Rat PSMD13 Protein Mammalian Cell His
Rat PSMD13-4445R Recombinant Rat PSMD13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PSMD13-4445R-B Recombinant Rat PSMD13 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey PSMD13-823C Recombinant Cynomolgus PSMD13 Protein, His-tagged Mammalian Cell His
Cynomolgus Monkey PSMD13-566C-B Recombinant Cynomolgus Monkey PSMD13 Protein Pre-coupled Magnetic Beads HEK293
Cynomolgus Monkey PSMD13-566C Recombinant Cynomolgus Monkey PSMD13 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Zebrafish PSMD13-11185Z Recombinant Zebrafish PSMD13 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PSMD13 Related Articles

PSMD13 involved in several pathways and played different roles in them. We selected most pathways PSMD13 participated on our site, such as Proteasome, Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMD13 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
ProteasomePSMA7;IFNG;PSMD4;PSMB4;PSMB11;PSMA6;PSMD8;PSMD6;PSMA3
Epstein-Barr virus infectionPOLR3E;EIF2AK3;HLA-E;CD38;MDM2;HLA-F;CD58;HLA-DQA1;MAPK11

PSMD13 has several biochemical functions, for example, structural molecule activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMD13 itself. We selected most functions PSMD13 had, and list some proteins which have the same functions with PSMD13. You can find most of the proteins on our site.

Function Related Protein
structural molecule activityLAMC3;FGA;CDC42SE2;FGB;SPRR2G;ASPH;COL15A1B;COPE;SNTA1

PSMD13 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMD13 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMD13.

PSMD4; TRAF6; PSMD14; PSMC1; UCHL5; NFKB2; 51464989; PSMD11; PSMD12; PSMA7; PSMD3; EIF1B; GH1; FES

Li, SH; Izumi, T; et al. Rescue of Enzymatic Function for Disease-associated RPE65 Proteins Containing Various Missense Mutations in Non-active Sites. JOURNAL OF BIOLOGICAL CHEMISTRY 289:18943-18956(2014).
Bi, W; Zhu, LH; et al. Investigations into the Role of 26S Proteasome Non-ATPase Regulatory Subunit 13 in Neuroinflammation. NEUROIMMUNOMODULATION 21:331-337(2014).
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