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PSMD3

Official Full Name

proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
Overview

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid.
Synonyms

PSMD3; proteasome (prosome, macropain) 26S subunit, non-ATPase, 3; tissue specific transplantation antigen 2 , TSTA2; 26S proteasome non-ATPase regulatory subunit 3; P58; Rpn3; S3; 26S proteasome non ATPase regulatory subunit 3; 26S proteasome regulatory subunit RPN3; 26S proteasome regulatory subunit S3; OTTHUMP00000164347; Proteasome (prosome, macropain) 26S subunit non ATPase 3; Proteasome subunit p58; PSMD3_HUMAN; Tissue specific transplantation antigen 2; TSTA2;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Chicken
Human
Mouse
Rhesus Macaque
Zebrafish

Source

HEK293
HEK293T
In Vitro Cell Free System
Mammalian Cell
Wheat Germ

Tag

His
His (Fc)
Avi
Myc
DDK
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Protein Length	Price
Human	PSMD3-30427TH	Recombinant Human PSMD3	Wheat Germ	N/A	100 amino acids	Inquiry
Human	PSMD3-30428TH	Recombinant Human PSMD3	Wheat Germ	N/A	534 amino acids	Inquiry
Human	PSMD3-2749HCL	Recombinant Human PSMD3 293 Cell Lysate	HEK293	N/A		Inquiry
Human	PSMD3-6294H	Recombinant Human PSMD3 Protein, Myc/DDK-tagged, C13 and N15-labeled	HEK293T	Myc/DDK		Inquiry
Human	PSMD3-408HF	Recombinant Full Length Human PSMD3 Protein	In Vitro Cell Free System		534 amino acids	Inquiry
Mouse	PSMD3-13594M	Recombinant Mouse PSMD3 Protein	Mammalian Cell	His		Inquiry
Mouse	Psmd3-5194M	Recombinant Mouse Psmd3 Protein, Myc/DDK-tagged	HEK293T	Myc/DDK		Inquiry
Mouse	PSMD3-7222M	Recombinant Mouse PSMD3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Mouse	PSMD3-7222M-B	Recombinant Mouse PSMD3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	PSMD3-3671R	Recombinant Rhesus monkey PSMD3 Protein, His-tagged	Mammalian Cell	His		Inquiry
Rhesus Macaque	PSMD3-3489R-B	Recombinant Rhesus Macaque PSMD3 Protein Pre-coupled Magnetic Beads	HEK293			Inquiry
Rhesus Macaque	PSMD3-3489R	Recombinant Rhesus Macaque PSMD3 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi		Inquiry
Zebrafish	PSMD3-10851Z	Recombinant Zebrafish PSMD3	Mammalian Cell	His		Inquiry
Chicken	PSMD3-3015C	Recombinant Chicken PSMD3	Mammalian Cell	His		Inquiry

Involved Pathway
Protein Function
Interacting Protein

PSMD3 involved in several pathways and played different roles in them. We selected most pathways PSMD3 participated on our site, such as Proteasome, Epstein-Barr virus infection, which may be useful for your reference. Also, other proteins which involved in the same pathway with PSMD3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Proteasome	PSMC1B;PSME2;SHFM1;PSMC2;PSMB11B;PSMC1;PSME4;PSMC1A;PSMD12
Epstein-Barr virus infection	MAPK10;PTMA;YWHAE;FCER2;RBPJ;CCNA2;EP300;SNW1;MAPK8

PSMD3 has several biochemical functions, for example, enzyme regulator activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PSMD3 itself. We selected most functions PSMD3 had, and list some proteins which have the same functions with PSMD3. You can find most of the proteins on our site.

Function	Related Protein
enzyme regulator activity	APOC3;EIF2B1;SEPT2;PSMD3;DPM2;PPP1R7;ATP6V1H;GCLM;PSMD1
protein binding	UBE2Q1;RNF168;HK2;SRPK3;NDRG4;SLC22A3;TNP1;SELS;FHL1

PSMD3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PSMD3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PSMD3.

UCHL5; PSMD14; ZBTB43; SHFM1; CEP44; VCAM1; PLCG2