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PTDSS2

  • Official Full Name

    phosphatidylserine synthase 2

  • Overview

    Phosphatidylserine (PS) accounts for 5 to 10% of cell membrane phospholipids. In addition to its role as a structural;component, PS is involved in cell signaling, blood coagulation, and apoptosis. PS is synthesized by a;calcium-dependent base-exchange reaction catalyzed by PS synthases (EC 2.7.8.8), like PTDSS2, that exchange L-serine;for the polar head group of phosphatidylcholine (PC) or phosphatidylethanolamine (PE) (Sturbois-Balcerzak et al., 2001;(PubMed 11084049)).
  • Synonyms

    PTDSS2; phosphatidylserine synthase 2; PSS2; PSS-2; ptdSer synthase 2; serine-exchange enzyme II; FLJ46373;

  • Recombinant Proteins
  • Protein Pre-coupled Magnetic Beads
  • Chicken
  • Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
  • Danio rerio (Zebrafish) (Brachydanio rerio)
  • Homo sapiens (Human)
  • Mouse
  • Mus musculus (Mouse)
  • Rat
  • Rattus norvegicus (Rat)
  • Xenopus tropicalis (Western clawed frog) (Silurana tropicalis)
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
Species Cat.# Product name Source (Host) Tag Protein Length Price
Mouse PTDSS2-13630M Recombinant Mouse PTDSS2 Protein Mammalian Cell His
Mouse PTDSS2-7248M Recombinant Mouse PTDSS2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Mouse PTDSS2-7248M-B Recombinant Mouse PTDSS2 Protein Pre-coupled Magnetic Beads HEK293
Rat PTDSS2-4799R Recombinant Rat PTDSS2 Protein Mammalian Cell His
Rat PTDSS2-4458R Recombinant Rat PTDSS2 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PTDSS2-4458R-B Recombinant Rat PTDSS2 Protein Pre-coupled Magnetic Beads HEK293
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus) RFL29230CF Recombinant Full Length Cricetulus Griseus Phosphatidylserine Synthase 2(Ptdss2) Protein, His-Tagged E.coli expression system His Full Length (1-474)
Danio rerio (Zebrafish) (Brachydanio rerio) RFL35910DF Recombinant Full Length Danio Rerio Phosphatidylserine Synthase 2(Ptdss2) Protein, His-Tagged E.coli expression system His Full Length (1-452)
Homo sapiens (Human) RFL2287HF Recombinant Full Length Human Phosphatidylserine Synthase 2(Ptdss2) Protein, His-Tagged E.coli expression system His Full Length (1-487)
Mus musculus (Mouse) RFL29794MF Recombinant Full Length Mouse Phosphatidylserine Synthase 2(Ptdss2) Protein, His-Tagged E.coli expression system His Full Length (1-473)
Rattus norvegicus (Rat) RFL8956RF Recombinant Full Length Rat Phosphatidylserine Synthase 2(Ptdss2) Protein, His-Tagged E.coli expression system His Full Length (1-471)
Xenopus tropicalis (Western clawed frog) (Silurana tropicalis) RFL33884XF Recombinant Full Length Xenopus Tropicalis Phosphatidylserine Synthase 2(Ptdss2) Protein, His-Tagged E.coli expression system His Full Length (1-474)
Chicken PTDSS2-4349C Recombinant Chicken PTDSS2 Mammalian Cell His
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • PTDSS2 Related Articles

PTDSS2 involved in several pathways and played different roles in them. We selected most pathways PTDSS2 participated on our site, such as Glycerophospholipid metabolism, Metabolic pathways, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTDSS2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Glycerophospholipid metabolismDGKZ;MBOAT2;AGXT2L1;LPIN2;AGPAT5;TAZ;PISD;GPD1A;DGKD
Metabolic pathwaysGRHPRB;PYGL;PPT2;INPP5L;GSTZ1;NME2B.1;POLR2J2;PDHA1A;PIGH

PTDSS2 has several biochemical functions, for example, CDP-diacylglycerol-serine O-phosphatidyltransferase activity, transferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PTDSS2 itself. We selected most functions PTDSS2 had, and list some proteins which have the same functions with PTDSS2. You can find most of the proteins on our site.

Function Related Protein
CDP-diacylglycerol-serine O-phosphatidyltransferase activity
transferase activityCCDC111;UGT5C3;FAM86;AANAT1;SBK1;FKTN;PRKCHB;BMPR1AA;UGT2B6

PTDSS2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTDSS2 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTDSS2.

Lee, S; Uchida, Y; et al. Impaired retrograde membrane traffic through endosomes in a mutant CHO cell defective in phosphatidylserine synthesis. GENES TO CELLS 17:728-736(2012).
Dissanayake, DRA; Wijewardana, TG; et al. Potential use of a liposome-encapsulated mixture of lipopolysaccharide core types (R1, R2, R3 and R4) of Escherichia coli in controlling colisepticaemia in chickens. JOURNAL OF MEDICAL MICROBIOLOGY 59:100-107(2010).
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