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PTGER3

  • Official Full Name

    prostaglandin E receptor 3 (subtype EP3)

  • Overview

    The protein encoded by this gene is a member of the G-protein coupled receptor family. This protein is one of four receptors identified for prostaglandin E2 (PGE2). This receptor may have many biological functions, which involve digestion, nervous system, kidney reabsorption, and uterine contraction activities. Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli. Multiple transcript variants encoding different isoforms have been found for this gene.
  • Synonyms

    PTGER3; prostaglandin E receptor 3 (subtype EP3); prostaglandin E2 receptor EP3 subtype; EP3; prostanoid EP3 receptor; PGE receptor, EP3 subtype; PGE2 receptor EP3 subtype; prostaglandin receptor (PGE-2); prostaglandin E receotor EP3 subtype 3 isoform; EP;

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Protein Pre-coupled Magnetic Beads
  • Assay Kits
  • Bos taurus (Bovine)
  • Chicken
  • Homo sapiens (Human)
  • Human
  • Mus musculus (Mouse)
  • Oryctolagus cuniculus (Rabbit)
  • Rat
  • Rattus norvegicus (Rat)
  • Sus scrofa (Pig)
  • E.coli
  • E.coli expression system
  • HEK293
  • Mammalian Cell
  • His
  • His (Fc)
  • Avi
  • Flag
  • His|GST
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human PTGER3-342H Recombinant Human PTGER3 Mammalian Cell His
Human PTGER3-2044H Recombinant Human PTGER3, His-tagged E.coli His 1-374aa
Human PTGER3-371H Recombinant Human PTGER3 Protein, His/GST-tagged E.coli His/GST Asn217~Arg390
Human PTGER3-2717HCL Recombinant Human PTGER3 293 Cell Lysate HEK293 N/A
Human PTGER3-1137HFL Recombinant Human PTGER3 protein, His&Flag-tagged HEK293 His&Flag 1-390 aa
Human PTGER3-3939H Recombinant Human PTGER3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human PTGER3-3939H-B Recombinant Human PTGER3 Protein Pre-coupled Magnetic Beads HEK293
Human PTGER3-6063H Recombinant Human PTGER3 Protein (Asn217-Gln359), N-His tagged E.coli N-His Asn217-Gln359
Rat PTGER3-4808R Recombinant Rat PTGER3 Protein Mammalian Cell His
Rat PTGER3-4467R Recombinant Rat PTGER3 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Rat PTGER3-4467R-B Recombinant Rat PTGER3 Protein Pre-coupled Magnetic Beads HEK293
Bos taurus (Bovine) RFL33900BF Recombinant Full Length Bovine Prostaglandin E2 Receptor Ep3 Subtype(Ptger3) Protein, His-Tagged E.coli expression system His Full Length (1-417)
Homo sapiens (Human) RFL35150HF Recombinant Full Length Human Prostaglandin E2 Receptor Ep3 Subtype(Ptger3) Protein, His-Tagged E.coli expression system His Full Length (1-390)
Mus musculus (Mouse) RFL7617MF Recombinant Full Length Mouse Prostaglandin E2 Receptor Ep3 Subtype(Ptger3) Protein, His-Tagged E.coli expression system His Full Length (1-365)
Oryctolagus cuniculus (Rabbit) RFL21017OF Recombinant Full Length Rabbit Prostaglandin E2 Receptor Ep3 Subtype(Ptger3) Protein, His-Tagged E.coli expression system His Full Length (1-411)
Rattus norvegicus (Rat) RFL21274RF Recombinant Full Length Rat Prostaglandin E2 Receptor Ep3 Subtype(Ptger3) Protein, His-Tagged E.coli expression system His Full Length (1-365)
Sus scrofa (Pig) RFL13520SF Recombinant Full Length Pig Prostaglandin E2 Receptor Ep3 Subtype(Ptger3) Protein, His-Tagged E.coli expression system His Full Length (1-373)
Chicken PTGER3-3417C Recombinant Chicken PTGER3 Mammalian Cell His
Kit-0990 Colorimetric Hydrogen Peroxide Assay Kit N/A
Kit-1487 PTGER3 CHO-K1 β-Arrestin GPCR Assay Kit N/A
Kit-1099 Sialic Acid (NANA) Colorimetric/Fluorometric Assay Kit N/A
Kit-1488 cAMP PTGER3 CHO-K1 GPCR Assay Kit N/A
  • Involved Pathway
  • Protein Function
  • Interacting Protein

PTGER3 involved in several pathways and played different roles in them. We selected most pathways PTGER3 participated on our site, such as Calcium signaling pathway, cAMP signaling pathway, Neuroactive ligand-receptor interaction, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTGER3 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Calcium signaling pathwayCAMK2D1;ADRB3A;SLC25A5;ATP2B2;PLCB4;HRH2;GNA11A;DRD1B;TACR1B
cAMP signaling pathwaySOX9;RAC1;CALM2;ATP2A2;RAP1A;PIK3CB;GRIN2D;PAK1;ATP1B2
Neuroactive ligand-receptor interactionLPAR6;CHRNA5;GLRA1;MTNR1BB;TRPV1;PRL2;ADRB3B;AGTR2;CHRNB3B
Regulation of lipolysis in adipocytesAdcy4;PIK3CG;PLIN1;PTGS2;PRKACG;PDE3B;GNAI1;GNAI2;AQP7
Pathways in cancerWNT1;ITGA2;FGF17;TFG;SMAD2;RET;WNT9A;SMAD3;NRAS

PTGER3 has several biochemical functions, for example, RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding, prostaglandin E receptor activity. Some of the functions are cooperated with other proteins, some of the functions could acted by PTGER3 itself. We selected most functions PTGER3 had, and list some proteins which have the same functions with PTGER3. You can find most of the proteins on our site.

Function Related Protein
RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA bindingPPARG;RORB;NR0B1;NR2F5;ESR2;NR1I2;PPARAB;NR5A1A;NR2E3
prostaglandin E receptor activityPTGER1B;PTGER4;PTGER1C;PTGER4A;PTGER1A;PTGER3;PTGER2;PTGER2B;PTGER4C

PTGER3 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTGER3 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTGER3.

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