PTPMT1
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Official Full Name
protein tyrosine phosphatase, mitochondrial 1
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Overview
Protein phosphatase that specifically mediates dephosphorylation of mitochondrial proteins, thereby playing an essential role in ATP production. Has probably a preference for proteins phosphorylated on Ser and/or Thr residues compared to proteins phosphorylated on Tyr residues. Probably involved in regulation of insulin secretion in pancreatic beta cells. -
Synonyms
PTPMT1; protein tyrosine phosphatase, mitochondrial 1; protein-tyrosine phosphatase mitochondrial 1; DUSP23; MOSP; PLIP; PTEN-like phosphatase; phosphoinositide lipid phosphatase; NB4 apoptosis/differentiation related protein; PNAS-129; FLJ46081;
- Recombinant Proteins
- Cell & Tissue Lysates
- Protein Pre-coupled Magnetic Beads
- Chicken
- Human
- Rhesus Macaque
- Zebrafish
- E. coli
- E.coli
- HEK293
- Mammalian Cell
- His
- His (Fc)
- Avi
- SUMO
- N/A
- N
Species | Cat.# | Product name | Source (Host) | Tag | Protein Length | Price |
---|---|---|---|---|---|---|
Human | PTPMT1-31117TH | Recombinant Human PTPMT1, His-tagged | E.coli | His | 174 amino acids | |
Human | PTPMT1-2547H | Active Recombinant Human PTPMT1 protein(Lys28-Thr201), His-tagged | E. coli | N-His | Lys28-Thr201 | |
Human | PTPMT1-1436HCL | Recombinant Human PTPMT1 cell lysate | N/A | |||
Human | PTPMT1-4636H | Recombinant Human PTPMT1 protein, His-SUMO-tagged | E.coli | His-SUMO | 28-201aa | |
Rhesus Macaque | PTPMT1-3703R | Recombinant Rhesus monkey PTPMT1 Protein, His-tagged | Mammalian Cell | His | ||
Rhesus Macaque | PTPMT1-3520R | Recombinant Rhesus Macaque PTPMT1 Protein, His (Fc)-Avi-tagged | HEK293 | His (Fc)-Avi | ||
Rhesus Macaque | PTPMT1-3520R-B | Recombinant Rhesus Macaque PTPMT1 Protein Pre-coupled Magnetic Beads | HEK293 | |||
Zebrafish | PTPMT1-5044Z | Recombinant Zebrafish PTPMT1 | Mammalian Cell | His | ||
Chicken | PTPMT1-5223C | Recombinant Chicken PTPMT1 | Mammalian Cell | His |
- Involved Pathway
- Protein Function
- Interacting Protein
- PTPMT1 Related Articles
PTPMT1 involved in several pathways and played different roles in them. We selected most pathways PTPMT1 participated on our site, such as 3-phosphoinositide degradation, Glycerophospholipid biosynthesis, Metabolism, which may be useful for your reference. Also, other proteins which involved in the same pathway with PTPMT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
Pathway Name | Pathway Related Protein |
---|---|
3-phosphoinositide degradation | PTPMT1;INPP5F |
Glycerophospholipid biosynthesis | PTPMT1;AWAT1;CEPT1;AGPAT1;STIL;SLC44A5B;DGAT1B;PHOSPHO1;ABHD3 |
Metabolism | SLC25A2;ACOT8;COQ7;COX10;SLC35B3;MED29;DDAH2;UGT1B1;SLC35D1A |
Metabolism of lipids and lipoproteins | APOA5;STARD5;CPTP;INSIG2;ABHD4;BCHE;CDS1;ARSE;ACOT13 |
Phospholipid metabolism | DGAT1B;TPTE;CDS1;CEPT1;SACM1L;PTPMT1;PLBD1;CEPT1A;PITPNB |
Synthesis of PG | PTPMT1;PLD6 |
PTPMT1 has several biochemical functions, for example, phosphatidylglycerophosphatase activity, phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PTPMT1 itself. We selected most functions PTPMT1 had, and list some proteins which have the same functions with PTPMT1. You can find most of the proteins on our site.
Function | Related Protein |
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phosphatidylglycerophosphatase activity | |
phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity | INPP5E;OCRL;SYNJ2;INPP5B;PTPMT1;EPM2A |
protein binding | RABGAP1L;TMEM119;KAL1;RPRD1B;NUDC;CD74;HOXA1;CEP72;EDEM1 |
protein tyrosine phosphatase activity | PTPN9;PTPN14;PTPN23A;KIAA1274;MTMR6;SSH2B;CDC14A;PTP4A2A;EYA2 |
protein tyrosine/serine/threonine phosphatase activity | DUSP3B;PTPDC1;DUSP23B;SACM1LB;PTP4A1;SSH2;CDC14A;SSH2B;DUSP11 |
PTPMT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PTPMT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of PTPMT1.
MDFI; RGS20; KRTAP2-3; TRIM27; KRTAP5-9; KRTAP10-7
- Q&As
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