Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953 Learn More

QTRT1

Official Full Name

queuine tRNA-ribosyltransferase 1
Overview

This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a;heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine;queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of;this gene is located on the long arm of chromosome X.
Synonyms

QTRT1; queuine tRNA-ribosyltransferase 1; queuine tRNA-ribosyltransferase; TGT; tRNA guanine transglycosylase; Guanine insertion enzyme; Queuine tRNA ribosyltransferase; TGUT; tRNA-guanine transglycosylase; FP3235;

Type

Recombinant Proteins
Cell & Tissue Lysates
Protein Pre-coupled Magnetic Beads

Species

Human
Mouse
Rat
Zebrafish

Source

E.coli
HEK293
Mammalian Cell

Tag

His
His (Fc)
Avi
N/A

Species	Cat.#	Product name	Source (Host)	Tag	Price
Human	QTRT1-79H	Recombinant Human QTRT1, His-tagged	E.coli	His	Inquiry
Human	QTRT1-2634HCL	Recombinant Human QTRT1 293 Cell Lysate	HEK293	N/A	Inquiry
Mouse	QTRT1-13773M	Recombinant Mouse QTRT1 Protein	Mammalian Cell	His	Inquiry
Mouse	QTRT1-7330M	Recombinant Mouse QTRT1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Mouse	QTRT1-7330M-B	Recombinant Mouse QTRT1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Rat	QTRT1-4869R	Recombinant Rat QTRT1 Protein	Mammalian Cell	His	Inquiry
Rat	QTRT1-4528R	Recombinant Rat QTRT1 Protein, His (Fc)-Avi-tagged	HEK293	His (Fc)-Avi	Inquiry
Rat	QTRT1-4528R-B	Recombinant Rat QTRT1 Protein Pre-coupled Magnetic Beads	HEK293		Inquiry
Zebrafish	QTRT1-11243Z	Recombinant Zebrafish QTRT1	Mammalian Cell	His	Inquiry

Involved Pathway
Protein Function
Interacting Protein

QTRT1 involved in several pathways and played different roles in them. We selected most pathways QTRT1 participated on our site, such as Gene Expression, tRNA modification in the nucleus and cytosol, tRNA processing, which may be useful for your reference. Also, other proteins which involved in the same pathway with QTRT1 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name	Pathway Related Protein
Gene Expression	EEF1A2;ZNF184;PHF19;EXOSC8;ZNF740;ZNF485;SNAPC3;ZNF19;PRDX2
tRNA modification in the nucleus and cytosol	TRMT11;OSGEP;TRMT112;TP53RK;QTRT1;TYW5;TRMT5;THG1L;TRDMT1
tRNA processing	QTRT1;METTL1;POP7;KIAA1456;RPP40;LCMT2;TRMT1;TSEN34;RPP38

QTRT1 has several biochemical functions, for example, metal ion binding, contributes_to queuine tRNA-ribosyltransferase activity, queuine tRNA-ribosyltransferase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by QTRT1 itself. We selected most functions QTRT1 had, and list some proteins which have the same functions with QTRT1. You can find most of the proteins on our site.

Function	Related Protein
metal ion binding	UBA2;PDE4A;GNAQ;TNKS2;ZNF79;MEP1A.1;KDM8;PDE4C;MTF1
contributes_to queuine tRNA-ribosyltransferase activity	QTRT1;QTRTD1;MANEA
queuine tRNA-ribosyltransferase activity

QTRT1 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with QTRT1 here. Most of them are supplied by our site. Hope this information will be useful for your research of QTRT1.

ARF6; PA; ZBTB16; UNC119; SETDB1; COPS6; SH3GL3; NDUFA4L2