ramp2
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  • Official Full Name
  • receptor (G protein-coupled) activity modifying protein 2
  • Background
  • The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.
  • Synonyms
  • RAMP2; receptor (G protein-coupled) activity modifying protein 2; receptor (calcitonin) activity modifying protein 2 , receptor activity modifying protein 2; receptor activity-modifying protein 2; Calcitonin receptor like receptor activity modifying protein 2; CRLR activity modifying protein 2; OTTMUSP00000002615; OTTMUSP00000037624; Receptor (calcitonin) activity modifying protein 2; Receptor activity modifying protein 2; Receptor activity modifying protein 2 isoform; RP23-281C18.6; CRLR activity-modifying protein 2; receptor-activity-modifying protein 2; calcitonin receptor-like receptor activity modifying protein 2; calcitonin-receptor-like receptor activity-modifying protein 2
Cat.#:RAMP2-2171HTag:GST
Source (Host):E. coliSpecies:Human
Product nameRecombinant Human RAMP2, GST-tagged
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Cat.#:RAMP2-4920RTag:His
Source (Host):Mammalian CellsSpecies:Rat
Product nameRecombinant Rat RAMP2 Protein
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Cat.#:RAMP2-3751CTag:His
Source (Host):Mammalian CellsSpecies:Chicken
Product nameRecombinant Chicken RAMP2
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Cat.#:RAMP2-6403ZTag:His
Source (Host):Mammalian CellsSpecies:Zebrafish
Product nameRecombinant Zebrafish RAMP2
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Cat.#:RAMP2-2536HCLTag:
Source (Host):Species:Human
Product nameRecombinant Human RAMP2 293 Cell Lysate
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RAMP2 Related Articles

Berenguer-Daize, C; Boudouresque, F; et al. Adrenomedullin Blockade Suppresses Growth of Human Hormone-Independent Prostate Tumor Xenograft in Mice. CLINICAL CANCER RESEARCH 19:6138-6150(2013).
Iesato, Y; Toriyama, Y; et al. Adrenomedullin-RAMP2 System Is Crucially Involved in Retinal Angiogenesis. AMERICAN JOURNAL OF PATHOLOGY 182:2380-2390(2013).