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Official Full Name
Ras association (RalGDS/AF-6) domain family member 5
This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene.
RASSF5; Ras association (RalGDS/AF-6) domain family member 5; ras association domain-containing protein 5; new ras effector 1; Rap1-binding protein; novel ras effector 1; Ras association (RalGDS/AF-6) domain family 5; regulator for cell adhesion and polarization enriched in lymphoid tissues; Rapl; Maxp1; Nore1; Nore1A; Nore1B; AU042887; 1300019G20Rik; MGC107647