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Official Full Name
retinoblastoma binding protein 6
The retinoblastoma tumor suppressor (pRB) protein binds with many other proteins. In various human cancers, pRB suppresses cellular proliferation and is inactivated. Cell cycle-dependent phosphorylation regulates the activity of pRB. This gene encodes a protein which binds to underphosphorylated but not phosphorylated pRB. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.
RBBP6; retinoblastoma binding protein 6; E3 ubiquitin-protein ligase RBBP6; protein P2P-R; retinoblastoma-binding protein 6; proliferation potential-related protein; p53-associated cellular protein of testis; PACT; P2P-R; C77662; AI316869; BB233631; 4933422O15Rik; C030034J04Rik; MGC32263