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S100A7

  • Official Full Name

    S100 calcium binding protein A7

  • Overview

    The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. This protein is markedly over-expressed in the skin lesions of psoriatic patients, but is excluded as a candidate gene for familial psoriasis susceptibility. The exact function of this protein is not known. [provided by RefSeq, Jul 2008]
  • Synonyms

    S100A7; S100 calcium binding protein A7; PSOR1; S100A7c; protein S100-A7; psoriasin 1; S100 calcium-binding protein A7 (psoriasin 1);

  • Recombinant Proteins
  • Cell & Tissue Lysates
  • Antibody
  • Protein Pre-coupled Magnetic Beads
  • Bovine
  • Cattle
  • Human
  • E. coli
  • E.coli
  • HEK293
  • HEK293F
  • HEK293T
  • In Vitro Cell Free System
  • Mammalian cells
  • Mouse
  • Rabbit
  • Wheat Germ
  • C
  • His
  • Flag
  • GST
  • His (Fc)
  • Avi
  • His|GST
  • Myc
  • DDK
  • N/A
  • N
Species Cat.# Product name Source (Host) Tag Protein Length Price
Human S100A7-431H Recombinant Human S100 Calcium Binding Protein A7 E.coli N/A
Human S100A7-2491H Recombinant Human S100A7, GST-tagged E.coli GST 1-101aa
Human S100A7-3095H Recombinant Human S100A7, None tagged E.coli N/A
Human S100A7-3494H Recombinant Human S100A7, His-tagged E.coli His
Human S100A7-185H Recombinant Human S100A7 protein, GST-tagged Wheat Germ GST
Human S100A7-2088HCL Recombinant Human S100A7 293 Cell Lysate HEK293 N/A
Human S100A7-4977H Recombinant Human S100A7 Protein, Myc/DDK-tagged, C13 and N15-labeled HEK293T Myc/DDK
Human CAB11596RH Rabbit Monoclonal Antibody to Human S100 Calcium Binding Protein A7 Rabbit N/A
Human S100A7-6218H Recombinant Human S100A7 Protein (Met1-Gln101), N-His tagged E.coli N-His Met1-Gln101
Human S100A7-633HF Recombinant Full Length Human S100A7 Protein, GST-tagged In Vitro Cell Free System GST 101 amino acids
Human S100A7-1942H Recombinant Human S100A7 Protein, His (Fc)-Avi-tagged HEK293 His (Fc)-Avi
Human S100A7-2884H Recombinant Human Full length S100A7 protein(1-101 aa), C-His-tagged E. coli C-His 1-101 aa
Human CAB11595MH Mouse Monoclonal Antibody to Human S100 Calcium Binding Protein A7 Mouse N/A
Human S100A7-637HFL Recombinant Full Length Human S100A7 Protein, C-Flag-tagged Mammalian cells Flag
Human S100A7-1942H-B Recombinant Human S100A7 Protein Pre-coupled Magnetic Beads HEK293
Bovine S100A7-143B Recombinant Bovine S100A7 Protein, His/GST-tagged E.coli His/GST Met1~Gln101
Cattle S100A7-1212C Recombinant Cattle S100A7 Protein, GST-tagged E.coli N-GST Met1-Gln101
Cattle S100A7-1213C Recombinant Cattle S100A7 Protein, His-tagged HEK293F N-His Met1-Gln101
  • Involved Pathway
  • Protein Function
  • Interacting Protein
  • S100A7 Related Articles
  • S100A7 Related Research Area

S100A7 involved in several pathways and played different roles in them. We selected most pathways S100A7 participated on our site, such as Validated targets of C-MYC transcriptional repression, which may be useful for your reference. Also, other proteins which involved in the same pathway with S100A7 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

Pathway Name Pathway Related Protein
Validated targets of C-MYC transcriptional repressionDNTT;TMEFF2;MXD4;TMEM126A;CSDE1;LGALS1;ZFP36L1;S100A7;CLU

S100A7 has several biochemical functions, for example, RAGE receptor binding, calcium ion binding, protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by S100A7 itself. We selected most functions S100A7 had, and list some proteins which have the same functions with S100A7. You can find most of the proteins on our site.

Function Related Protein
RAGE receptor bindingS100P;HMGB2;S100A8;HMGB1;S100A13;S100A4;S100B;S100A9;S100A7
calcium ion bindingEFHC2;ITSN2;PVALB7;MYL12.1;ICN2;PROS1;ASPH;MMP28;EFCC1
protein bindingAEN;CALCOCO1;SFTPD;PBK;TIMM10;MAP2K6;ATP6V1E2;TAGLN2;PALLD
zinc ion bindingLIMK1;ZDHHC16B;KDM2A;MBTD1;TRAF2;ADAT2;RLIM;RNF4;MMP2

S100A7 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with S100A7 here. Most of them are supplied by our site. Hope this information will be useful for your research of S100A7.

RANBP9; PPP2R2B; MAP3K3; PAK7; RASSF10; RASSF9; ESR1; IFIT1; CFTR; VCAM1; CD81; P/V/C; K3

Lapeire, L; Hendrix, A; et al. Cancer-Associated Adipose Tissue Promotes Breast Cancer Progression by Paracrine Oncostatin M and Jak/STAT3 Signaling. CANCER RESEARCH 74:6806-6819(2014).
Witte, E; Kokolakis, G; et al. IL-19 Is a Component of the Pathogenetic IL-23/IL-17 Cascade in Psoriasis. JOURNAL OF INVESTIGATIVE DERMATOLOGY 134:2757-2767(2014).
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